Mutation of the fourth cytoplasmic loop of rhodopsin affects binding of transducin and peptides derived from the carboxyl-terminal sequences of transducin alpha and gamma subunits.
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Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimersAutosomal recessive retinitis pigmentosa and E150K mutation in the opsin geneAdvances in Determination of a High-Resolution Three-Dimensional Structure of Rhodopsin, a Model of G-Protein-Coupled Receptors (GPCRs)Helix Dipole Movement and Conformational Variability Contribute to Allosteric GDP Release in Gα i Subunits † , ‡Functional Role of the C-Terminal Amphipathic Helix 8 of Olfactory Receptors and Other G Protein-Coupled ReceptorsSelective interactions between helix VIII of the human mu-opioid receptors and the C terminus of periplakin disrupt G protein activationDeletion in the OA1 gene in a family with congenital X linked nystagmusRhodopsin-transducin interface: studies with conformationally constrained peptides.Truncation of the A1 adenosine receptor reveals distinct roles of the membrane-proximal carboxyl terminus in receptor folding and G protein couplingInteraction of neurochondrin with the melanin-concentrating hormone receptor 1 interferes with G protein-coupled signal transduction but not agonist-mediated internalizationMolecular dynamics simulations reveal specific interactions of post-translational palmitoyl modifications with rhodopsin in membranes.Mapping of contact sites in complex formation between transducin and light-activated rhodopsin by covalent crosslinking: use of a photoactivatable reagent.Constraints on the conformation of the cytoplasmic face of dark-adapted and light-excited rhodopsin inferred from antirhodopsin antibody imprints.Modulating G-protein coupled receptor/G-protein signal transduction by small molecules suggested by virtual screening.Role of helix 8 of the thyrotropin-releasing hormone receptor in phosphorylation by G protein-coupled receptor kinase.How a small change in retinal leads to G-protein activation: initial events suggested by molecular dynamics calculations.The amino terminus of the fourth cytoplasmic loop of rhodopsin modulates rhodopsin-transducin interaction.The role of palmitoylation in signalling, cellular trafficking and plasma membrane localization of protease-activated receptor-2.In channelrhodopsin-2 Glu-90 is crucial for ion selectivity and is deprotonated during the photocycle.G protein-coupled receptor rhodopsin: a prospectus.Dancing with multiple partners.The cannabinoid type-1 receptor carboxyl-terminus, more than just a tail.Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation.Differential regulation of two palmitoylation sites in the cytoplasmic tail of the beta1-adrenergic receptorStructural basis of G protein-coupled receptor-G protein interactions.A mechanistic role of Helix 8 in GPCRs: Computational modeling of the dopamine D2 receptor interaction with the GIPC1-PDZ-domain.Conformational changes of G protein-coupled receptors during their activation by agonist binding.Defining the interface between the C-terminal fragment of alpha-transducin and photoactivated rhodopsin.Functions of DPLIY motif and helix 8 of human melanocortin-3 receptor.Light-induced damage to the retina: role of rhodopsin chromophore revisited.Conformational changes involved in G-protein-coupled-receptor activationG protein betagamma complex translocation from plasma membrane to Golgi complex is influenced by receptor gamma subunit interactionStructure and dynamics of dark-state bovine rhodopsin revealed by chemical cross-linking and high-resolution mass spectrometry.A GIPC1-Palmitate Switch Modulates Dopamine Drd3 Receptor Trafficking and Signaling.Propagation of conformational changes during μ-opioid receptor activation.Structural and kinetic modeling of an activating helix switch in the rhodopsin-transducin interfaceAgonist-dependent phosphorylation of the formyl peptide receptor is regulated by the membrane proximal region of the cytoplasmic tail.Novel structural and functional insights into M3 muscarinic receptor dimer/oligomer formation.The cytoplasmic tail of the D1A receptor subtype: identification of specific domains controlling dopamine cellular responsiveness.Role of the fourth intracellular loop of D1-like dopaminergic receptors in conferring subtype-specific signaling properties.
P2860
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P2860
Mutation of the fourth cytoplasmic loop of rhodopsin affects binding of transducin and peptides derived from the carboxyl-terminal sequences of transducin alpha and gamma subunits.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
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2000年学术文章
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2000年學術文章
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2000年學術文章
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name
Mutation of the fourth cytopla ...... ucin alpha and gamma subunits.
@en
Mutation of the fourth cytopla ...... ucin alpha and gamma subunits.
@nl
type
label
Mutation of the fourth cytopla ...... ucin alpha and gamma subunits.
@en
Mutation of the fourth cytopla ...... ucin alpha and gamma subunits.
@nl
prefLabel
Mutation of the fourth cytopla ...... ucin alpha and gamma subunits.
@en
Mutation of the fourth cytopla ...... ucin alpha and gamma subunits.
@nl
P2093
P2860
P356
P1476
Mutation of the fourth cytopla ...... ucin alpha and gamma subunits.
@en
P2093
P2860
P304
P356
10.1074/JBC.275.3.1937
P407
P577
2000-01-01T00:00:00Z