Melatonin stimulates the nonamyloidogenic processing of βAPP through the positive transcriptional regulation of ADAM10 and ADAM17.
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Therapies for Prevention and Treatment of Alzheimer's DiseaseCurrent and future implications of basic and translational research on amyloid-β peptide production and removal pathwaysThe Polyherbal Wattana Formula Displays Anti-Amyloidogenic Properties by Increasing α-Secretase Activities.Prophylactic melatonin significantly reduces Alzheimer's neuropathology and associated cognitive deficits independent of antioxidant pathways in AβPP(swe)/PS1 mice.Melatonin regulates the transcription of βAPP-cleaving secretases mediated through melatonin receptors in human neuroblastoma SH-SY5Y cells.Therapeutic Potential of Secreted Amyloid Precursor Protein APPsα.Mechanisms of Melatonin in Alleviating Alzheimer's Disease.Regulation of Alpha-Secretase ADAM10 In vitro and In vivo: Genetic, Epigenetic, and Protein-Based Mechanisms.The Role of ADAM10 in Alzheimer's Disease.Combinatorial Treatment Effects in a Cell Culture Model of Alzheimer's Disease.Melatonin inhibits nucleus pulposus (NP) cell proliferation and extracellular matrix (ECM) remodeling via the melatonin membrane receptors mediated PI3K-Akt pathway.Melatonin Attenuates Memory Impairment, Amyloid-β Accumulation, and Neurodegeneration in a Rat Model of Sporadic Alzheimer's Disease.Alpha-Secretase ADAM10 Regulation: Insights into Alzheimer's Disease Treatment.Melatonin ameliorates amyloid beta-induced memory deficits, tau hyperphosphorylation and neurodegeneration via PI3/Akt/GSk3β pathway in the mouse hippocampus.Intranasal Lactoferrin Enhances α-Secretase-Dependent Amyloid Precursor Protein Processing via the ERK1/2-CREB and HIF-1α Pathways in an Alzheimer's Disease Mouse Model.Catalpol Inhibits Amyloid-β Generation Through Promoting α-Cleavage of APP in Swedish Mutant APP Overexpressed N2a Cells.
P2860
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P2860
Melatonin stimulates the nonamyloidogenic processing of βAPP through the positive transcriptional regulation of ADAM10 and ADAM17.
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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name
Melatonin stimulates the nonam ...... gulation of ADAM10 and ADAM17.
@en
Melatonin stimulates the nonam ...... gulation of ADAM10 and ADAM17.
@nl
type
label
Melatonin stimulates the nonam ...... gulation of ADAM10 and ADAM17.
@en
Melatonin stimulates the nonam ...... gulation of ADAM10 and ADAM17.
@nl
prefLabel
Melatonin stimulates the nonam ...... gulation of ADAM10 and ADAM17.
@en
Melatonin stimulates the nonam ...... gulation of ADAM10 and ADAM17.
@nl
P2093
P2860
P356
P1476
Melatonin stimulates the nonam ...... gulation of ADAM10 and ADAM17.
@en
P2093
Bruno Vincent
Claire Dubois
Duncan R Smith
Htut Htut Htoo
Jean-Francois Hernandez
Mayuri Shukla
Phitchayapak Wintachai
Piyarat Govitrapong
Rolf Postina
P2860
P304
P356
10.1111/JPI.12200
P577
2014-12-27T00:00:00Z