Msh3 is a limiting factor in the formation of intergenerational CTG expansions in DM1 transgenic mice.
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Fragile X syndrome: the FMR1 CGG repeat distribution among world populationsDNA triplet repeat expansion and mismatch repairRepeat-mediated genetic and epigenetic changes at the FMR1 locus in the Fragile X-related disordersA MutSβ-Dependent Contribution of MutSα to Repeat Expansions in Fragile X Premutation Mice?Ups and Downs: Mechanisms of Repeat Instability in the Fragile X-Related DisordersMutSβ promotes trinucleotide repeat expansion by recruiting DNA polymerase β to nascent (CAG)n or (CTG)n hairpins for error-prone DNA synthesisIsolated short CTG/CAG DNA slip-outs are repaired efficiently by hMutSbeta, but clustered slip-outs are poorly repaired.MSH2 ATPase domain mutation affects CTG*CAG repeat instability in transgenic mice.Diverse effects of individual mismatch repair components on transcription-induced CAG repeat instability in human cells.Progressive GAA.TTC repeat expansion in human cell lines.A novel approach to investigate tissue-specific trinucleotide repeat instability.Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genesGender and cell-type-specific effects of the transcription-coupled repair protein, ERCC6/CSB, on repeat expansion in a mouse model of the fragile X-related disordersA selective inhibitor of histone deacetylase 3 prevents cognitive deficits and suppresses striatal CAG repeat expansions in Huntington's disease miceXpa deficiency reduces CAG trinucleotide repeat instability in neuronal tissues in a mouse model of SCA1.Correlation of inter-locus polyglutamine toxicity with CAG•CTG triplet repeat expandability and flanking genomic DNA GC contentPotassium bromate, a potent DNA oxidizing agent, exacerbates germline repeat expansion in a fragile X premutation mouse modelMSH3 polymorphisms and protein levels affect CAG repeat instability in Huntington's disease miceMismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approachesMicrosatellite repeat instability and neurological disease.Purification, crystallization and preliminary X-ray diffraction analysis of the human mismatch repair protein MutSβHeterozygosity for a hypomorphic Polβ mutation reduces the expansion frequency in a mouse model of the Fragile X-related disorders.Repeat instability during DNA repair: Insights from model systemsLarge expansion of CTG•CAG repeats is exacerbated by MutSβ in human cells.Cancer risk among patients with myotonic muscular dystrophy.Instability of (CTG)n•(CAG)n trinucleotide repeats and DNA synthesisMSH3 Promotes Dynamic Behavior of Trinucleotide Repeat Tracts In Vivo.The Repeat Expansion Diseases: The dark side of DNA repair.Searching for non-B DNA-forming motifs using nBMST (non-B DNA motif search tool)Chromatin changes in the development and pathology of the Fragile X-associated disorders and Friedreich ataxia.DNA mismatch repair complex MutSβ promotes GAA·TTC repeat expansion in human cellsRole of mismatch repair enzymes in GAA·TTC triplet-repeat expansion in Friedreich ataxia induced pluripotent stem cells.Msh2-Msh3 interferes with Okazaki fragment processing to promote trinucleotide repeat expansions.Mutsβ generates both expansions and contractions in a mouse model of the Fragile X-associated disordersMutSβ and histone deacetylase complexes promote expansions of trinucleotide repeats in human cells.ATR protects the genome against CGG.CCG-repeat expansion in Fragile X premutation mice.The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder.Somatic expansion in mouse and human carriers of fragile X premutation alleles.A personal historical view of DNA mismatch repair with an emphasis on eukaryotic DNA mismatch repair.The mismatch repair system protects against intergenerational GAA repeat instability in a Friedreich ataxia mouse model.
P2860
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P2860
Msh3 is a limiting factor in the formation of intergenerational CTG expansions in DM1 transgenic mice.
description
2006 nî lūn-bûn
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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name
Msh3 is a limiting factor in t ...... nsions in DM1 transgenic mice.
@en
Msh3 is a limiting factor in t ...... nsions in DM1 transgenic mice.
@nl
type
label
Msh3 is a limiting factor in t ...... nsions in DM1 transgenic mice.
@en
Msh3 is a limiting factor in t ...... nsions in DM1 transgenic mice.
@nl
prefLabel
Msh3 is a limiting factor in t ...... nsions in DM1 transgenic mice.
@en
Msh3 is a limiting factor in t ...... nsions in DM1 transgenic mice.
@nl
P2093
P1433
P1476
Msh3 is a limiting factor in t ...... ansions in DM1 transgenic mice
@en
P2093
Claudine Junien
Cédric Savouret
Hein te Riele
Laurence Hubert
Laurent Foiry
P2888
P304
P356
10.1007/S00439-006-0164-7
P577
2006-03-22T00:00:00Z