about
[(Cp-R)M(CO)3] (M=Re or 99mTc) Arylsulfonamide, arylsulfamide, and arylsulfamate conjugates for selective targeting of human carbonic anhydrase IXPreparation and biological evaluation of cyclopentadienyl-based 99mTc-complexes [(Cp-R)99mTc(CO)3] mimicking benzamides for malignant melanoma targeting.Lanthanide(III) complexes of 4,10-bis(phosphonomethyl)-1,4,7,10-tetraazacyclododecane-1,7-diacetic acid (trans-H6do2a2p) in solution and in the solid state: structural studies along the series.Synthesis of organometallic ruthenium(II) complexes with strong activity against several human cancer cell lines.Radiometallated peptides for molecular imaging and targeted therapy.Bisphosphonates as radionuclide carriers for imaging or systemic therapy.New water-soluble ruthenium(II) cytotoxic complex: biological activity and cellular distribution.Important cytotoxicity of novel iron(II) cyclopentadienyl complexes with imidazole based ligands.Cellular uptake mechanisms of an antitumor ruthenium compound: the endosomal/lysosomal system as a target for anticancer metal-based drugs.New bifunctional metalloproteinase inhibitors: an integrated approach towards biological improvements and cancer therapy.Screening organometallic binuclear thiosemicarbazone ruthenium complexes as potential anti-tumour agents: cytotoxic activity and human serum albumin binding mechanism.Mono- and dicationic Re(I)/(99m)Tc(I) tricarbonyl complexes for the targeting of energized mitochondria.Synthesis and biological studies of pyrazolyl-diamine Pt(II) complexes containing polyaromatic DNA-binding groups.The [(Cp)M(CO)(3)] (M=Re, (99m)Tc) building block for imaging agents and bioinorganic probes: perspectives and limitations.[RuII(η⁵-C₅H₅)(bipy)(PPh₃)]⁺, a promising large spectrum antitumor agent: cytotoxic activity and interaction with human serum albumin.Novel estradiol based metal complexes of Tc-99m.99mTc(I)/Re(I) tricarbonyl complexes for in vivo targeting of melanotic melanoma: Synthesis and biological evaluation.Cytotoxic gold compounds: synthesis, biological characterization and investigation of their inhibition properties of the zinc finger protein PARP-1.Radiohalogenated 4-anilinoquinazoline-based EGFR-TK inhibitors as potential cancer imaging agents.Nuclear targeting with cell-specific multifunctional tricarbonyl M(I) (M is Re, (99m)Tc) complexes: synthesis, characterization, and cell studies.Pt(II) complexes with bidentate and tridentate pyrazolyl-containing chelators: synthesis, structural characterization and biological studies.Copper(II) complexes with tridentate pyrazole-based ligands: synthesis, characterization, DNA cleavage activity and cytotoxicity.Metal-based inhibition of poly(ADP-ribose) polymerase--the guardian angel of DNA.Synthesis, characterization and biological evaluation of In(III) complexes anchored by DOTA-like chelators bearing a quinazoline moiety.Re and Tc tricarbonyl complexes: from the suppression of NO biosynthesis in macrophages to in vivo targeting of inducible nitric oxide synthase.Tricarbonyl M(I) (M = Re, (99m)Tc) complexes bearing acridine fluorophores: synthesis, characterization, DNA interaction studies and nuclear targeting.Synthesis, characterization and cytotoxic activity of gallium(III) complexes anchored by tridentate pyrazole-based ligands.Synthesis and characterization of rhenium and technetium-99m tricarbonyl complexes bearing the 4-[3-bromophenyl]quinazoline moiety as a biomarker for EGFR-TK imaging.Radioiodinated ligands for the estrogen receptor: effect of different 7-cyanoalkyl chains on the binding affinity of novel iodovinyl-6-dehydroestradiols.A quinazoline-derivative DOTA-type gallium(III) complex for targeting epidermal growth factor receptors: synthesis, characterisation and biological studies.Synthesis, characterization, and evaluation of a novel 99mTc(CO)3 pyrazolyl conjugate of a peptide nucleic acid sequence.Melanoma targeting with alpha-melanocyte stimulating hormone analogs labeled with fac-[99mTc(CO)3]+: effect of cyclization on tumor-seeking properties.Pyrazolyl-diamine ligands that bear anthracenyl moieties and their rhenium(I) tricarbonyl complexes: synthesis, characterisation and DNA-binding properties.Radioiodination of new EGFR inhibitors as potential SPECT agents for molecular imaging of breast cancer.In vitro and in vivo evaluation of a novel 99mTc(CO)3-pyrazolyl conjugate of cyclo-(Arg-Gly-Asp-d-Tyr-Lys).TETA analogue containing one methylenephosphonate pendant arm: Lanthanide complexes and biological evaluation of its 153Sm and 166Ho complexes.(99m)Tc-tricarbonyl complexes functionalized with anthracenyl fragments: synthesis, characterization, and evaluation of their radiotoxic effects in murine melanoma cells.Reactivity of [Re[kappa(3)-H(mu-H)B(tim(Me))(2)](CO)(3)] (tim(Me) = 2-mercapto-1-methylimidazolyl) toward neutral substrates.Radiosynthesis and in vivo evaluation of a ¹⁸F-labelled styryl-benzoxazole derivative for β-amyloid targeting.Synthesis and structural characterization of unprecedented bis-asymmetric heteroscorpionate U(III) complexes: [U(kappa3-H2B(pztBu,Me)(pzMe,tBu))2I] and [U(kappa3-H2B(pztBu,Me)(pzMe2))2I].
P50
Q27677350-711F44DC-C56D-495C-BE52-BD53136435DAQ33546813-A8C6E57E-3A60-4F0B-9F31-19D3078AFCD9Q33601618-8B4DB12E-C45F-431A-A7A9-81B8DBA9525BQ34304457-06B5DC62-7D46-4D9D-8A3D-6F743620B0F2Q37847064-C463014B-5701-4E86-8A68-6893A4850A47Q37924117-9EC320CB-CBDA-48ED-88A0-70C8519C1379Q39075388-81D5A406-6063-48C3-A477-F16694BA770FQ39101770-4E8AB7F3-A877-4444-8B71-27D3107659F4Q39136843-072A5659-A3FC-4412-B4D4-B2769B9AEED2Q39164036-28AAE32B-F7B7-4A6C-B941-29262FAA2C33Q39177371-A7A734D6-59DD-4DF2-B643-C322A05EFF66Q39179014-66FD97F6-D1E4-40D7-89E7-A02E7680D729Q39265471-7AD651B4-6134-434E-9F68-D04626C8A006Q39278930-97E59F4B-8570-4E7F-A561-ED39555C1A1BQ39300142-F28DCD3D-15C8-42E5-AB74-301651A55C73Q39370522-EDE834B5-8022-4FE8-B19F-F1B030294529Q39383884-40ED9F3B-235B-4ECC-9279-2DB0C7176DFDQ39404168-17452F49-5FEB-443E-94C5-5C38955D8C26Q39444105-30193C99-5AE7-4CB7-AA6C-8112487FD736Q39517574-326AE2DF-4C51-4658-B43F-D81490BD5B75Q39554731-0968D5B8-4159-4B60-9B49-239F34C3301CQ39568247-2AC3CD75-7043-4EF8-90E0-2CF0589AEAD7Q39582316-580ACCF7-3E8B-4D77-ADAB-50C956486E20Q39632732-3C8B2073-E905-452E-A762-FE21187485E8Q39636827-90191F82-396B-4CAB-8D2E-6480FEA1E56FQ39677586-FE6DEA43-A32E-4C9D-A666-55AE10CCDACAQ39740868-B8C3791F-F1EC-4E66-A6F5-AD08006C878BQ39844317-CBB81B46-54B4-4072-BE5F-253E3AEA3A5BQ39909952-D7EBAAAE-6DDF-479B-AF7A-ECC87A735B57Q39917578-D6EFBF89-5E72-4394-9B98-CD5D5696F570Q39942160-7C3252FD-EDE4-4E92-842C-D58437EC8A65Q40027123-294BCC2A-9464-471A-8004-8109469E4722Q40038874-7294BBC8-E5D7-4B06-ACA3-B7B4EBDAEF2CQ40142924-FF987FC6-431F-4713-B812-0FF08A2AD0E8Q40156559-7EF82C22-B2C0-40DF-901D-873B9A8BC8B9Q42871525-05D835B6-CDBB-4F19-9655-C8E41407E099Q43251755-DFBF9F15-5A58-42C2-AC70-8FB482DAD447Q43972105-A7FBF079-9BC1-40EB-977E-52E2AD70012DQ44106943-4131ACA6-72BC-46FF-9EE4-F9EE7A6C706BQ44436080-2CEFDA0F-EFDE-43C4-BEE7-E87DEB16FEB4
P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Isabel Santos
@ast
Isabel Santos
@en
Isabel Santos
@es
Isabel Santos
@nl
Isabel Santos
@sl
type
label
Isabel Santos
@ast
Isabel Santos
@en
Isabel Santos
@es
Isabel Santos
@nl
Isabel Santos
@sl
prefLabel
Isabel Santos
@ast
Isabel Santos
@en
Isabel Santos
@es
Isabel Santos
@nl
Isabel Santos
@sl
P106
P1153
7102671694
P21
P31
P496
0000-0001-7362-0022