Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy. - Wikidata - awgldk - TriplyDB

Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy.

Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy.

http://www.wikidata.org/entity/Q53279352

about

Novel therapeutic targets for pancreatic cancer Molecular therapeutics in pancreas cancer The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells Cancer Stem Cells and Macrophages: Implications in Tumor Biology and Therapeutic Strategies Key players in pancreatic cancer-stroma interaction: Cancer-associated fibroblasts, endothelial and inflammatory cells Clinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathway Nodal signaling promotes a tumorigenic phenotype in human breast cancer Heterogeneity and targeting of pancreatic cancer stem cells Pancreatic cancer stem cells: emerging target for designing novel therapy Desmoplasia and chemoresistance in pancreatic cancer Persistent activation of pancreatic stellate cells creates a microenvironment favorable for the malignant behavior of pancreatic ductal adenocarcinoma Human Cerberus prevents nodal-receptor binding, inhibits nodal signaling, and suppresses nodal-mediated phenotypes Intracellular autofluorescence: a biomarker for epithelial cancer stem cells Concise Review: Stem Cells in Pancreatic Cancer: From Concept to Translation TGF-β family signaling in stem cells Multimodal Treatment Eliminates Cancer Stem Cells and Leads to Long-Term Survival in Primary Human Pancreatic Cancer Tissue Xenografts A synthetic triterpenoid CDDO-Im inhibits tumorsphere formation by regulating stem cell signaling pathways in triple-negative breast cancer The Metastatic Potential and Chemoresistance of Human Pancreatic Cancer Stem Cells Activin upregulation by NF-κB is required to maintain mesenchymal features of cancer stem-like cells in non-small cell lung cancer.The miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1.Sulforaphane counteracts aggressiveness of pancreatic cancer driven by dysregulated Cx43-mediated gap junctional intercellular communication Homozygous deletion of the activin A receptor, type IB gene is associated with an aggressive cancer phenotype in pancreatic cancer Activin-A signaling promotes epithelial-mesenchymal transition, invasion, and metastatic growth of breast cancer The IL-8/CXCR1 axis is associated with cancer stem cell-like properties and correlates with clinical prognosis in human pancreatic cancer cases.Cancer stem cells: involvement in pancreatic cancer pathogenesis and perspectives on cancer therapeutics.Targeting the K-Ras--JNK axis eliminates cancer stem-like cells and prevents pancreatic tumor formation.Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine.Patient-derived xenograft models: an emerging platform for translational cancer research MicroRNA-1246 expression associated with CCNG2-mediated chemoresistance and stemness in pancreatic cancer Identification of pluripotent and adult stem cell genes unrelated to cell cycle and associated with poor prognosis in multiple myeloma.Smarter drugs emerging in pancreatic cancer therapy.Triptolide reverses hypoxia-induced epithelial-mesenchymal transition and stem-like features in pancreatic cancer by NF-κB downregulation.Prognostic value of CD166 expression in cancers of the digestive system: a systematic review and meta-analysis.Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells Identification of a novel subpopulation of tumor-initiating cells from gemcitabine-resistant pancreatic ductal adenocarcinoma patients.Embryonic stem cell factors and pancreatic cancer Notch signaling induces epithelial-mesenchymal transition to promote invasion and metastasis in adenoid cystic carcinoma.Overexpression of Nodal induces a metastatic phenotype in pancreatic cancer cells via the Smad2/3 pathway Targeting cancer stem cells in solid tumors by vitamin D.Fibroblast α11β1 integrin regulates tensional homeostasis in fibroblast/A549 carcinoma heterospheroids

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Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy.

http://www.wikidata.org/entity/Q53279352

description

2011 nî lūn-bûn

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2011年の論文

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2011年学术文章

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2011年學術文章

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name

Nodal/Activin signaling drives ...... get for combined drug therapy.

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Nodal/Activin signaling drives ...... get for combined drug therapy.

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Nodal/Activin signaling drives ...... get for combined drug therapy.

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Nodal/Activin signaling drives ...... get for combined drug therapy.

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Nodal/Activin signaling drives ...... get for combined drug therapy.

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Nodal/Activin signaling drives ...... get for combined drug therapy.

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Nodal/Activin signaling drives ...... get for combined drug therapy.

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Christopher Heeschen

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David Álvaro Cebrián

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Elena Garcia

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Enza Lonardo

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Frank Berger

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Iker Rodriguez-Arabaolaza

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Irene Miranda-Lorenzo

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Juan Carlos Ramirez

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Maria-Theresa Mueller

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Peter Bartenstein

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