Non-genetic heterogeneity--a mutation-independent driving force for the somatic evolution of tumours.
about
Mitochondrial variability as a source of extrinsic cellular noiseLearning about the Importance of Mutation Prevention from Curable Cancers and Benign TumorsProtecting the normal in order to better kill the cancerPhenotypic noise: effects of post-transcriptional regulatory processes affecting mRNAEndogenous voltage gradients as mediators of cell-cell communication: strategies for investigating bioelectrical signals during pattern formationKilling me softly--future challenges in apoptosis researchHow changes in extracellular matrix mechanics and gene expression variability might combine to drive cancer progressionBistable cell fate specification as a result of stochastic fluctuations and collective spatial cell behaviourGene networks of fully connected triads with complete auto-activation enable multistability and stepwise stochastic transitionsNon-Darwinian dynamics in therapy-induced cancer drug resistance.Tracking the evolution of cancer cell populations through the mathematical lens of phenotype-structured equations.RNA Relics and Origin of LifeEndogenous retroviral promoter exaptation in human cancerEpithelial cancers in the post-genomic era: should we reconsider our lifestyle?Pre-clinical drug prioritization via prognosis-guided genetic interaction networksSlow protein fluctuations explain the emergence of growth phenotypes and persistence in clonal bacterial populationsIdentifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discoveryAutoregulation and heterogeneity in expression of human Cripto-1Ex vivo chemical cytometric analysis of protein tyrosine phosphatase activity in single human airway epithelial cellsStochasticity in the Genotype-Phenotype Map: Implications for the Robustness and Persistence of Bet-HedgingSystematic drug perturbations on cancer cells reveal diverse exit paths from proliferative stateHypothesis: Towards the origin of cancer epidemics and pathogenesisCellular heterogeneity and live cell arrays.Intersection of FOXO- and RUNX1-mediated gene expression programs in single breast epithelial cells during morphogenesis and tumor progression.Multigene expression-based predictors for sensitivity to Vorinostat and Velcade in non-small cell lung cancer.Individual histories and selection in heterogeneous populations.Modulating cell-to-cell variability and sensitivity to death ligands by co-drugging.Calcium Spikes in Epithelium: study on Drosophila early embryos.Persistence to anti-cancer treatments in the stationary to proliferating transition.Collective motions and specific effectors: a statistical mechanics perspective on biological regulationNanog variability and pluripotency regulation of embryonic stem cells--insights from a mathematical model analysis.Effect of transcription factor resource sharing on gene expression noiseMathematical models of the transitions between endocrine therapy responsive and resistant states in breast cancer.Unraveling the regulatory connections between two controllers of breast cancer cell fateNoise regulation by quorum sensing in low mRNA copy number systems.The role of incoherent microRNA-mediated feedforward loops in noise buffering.Noise-driven heterogeneity in the rate of genetic-variant generation as a basis for evolvability.Patterns of basal signaling heterogeneity can distinguish cellular populations with different drug sensitivities.Analysis of doxorubicin uptake in single human leukemia K562 cells using capillary electrophoresis coupled with laser-induced fluorescence detection.Cellular heterogeneity: do differences make a difference?
P2860
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P2860
Non-genetic heterogeneity--a mutation-independent driving force for the somatic evolution of tumours.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Non-genetic heterogeneity--a m ...... somatic evolution of tumours.
@en
Non-genetic heterogeneity--a m ...... somatic evolution of tumours.
@nl
type
label
Non-genetic heterogeneity--a m ...... somatic evolution of tumours.
@en
Non-genetic heterogeneity--a m ...... somatic evolution of tumours.
@nl
prefLabel
Non-genetic heterogeneity--a m ...... somatic evolution of tumours.
@en
Non-genetic heterogeneity--a m ...... somatic evolution of tumours.
@nl
P2093
P356
P1476
Non-genetic heterogeneity--a m ...... somatic evolution of tumours.
@en
P2093
Hannah Chang
P2888
P304
P356
10.1038/NRG2556
P577
2009-05-01T00:00:00Z