Bacterial cytolethal distending toxin promotes the development of dysplasia in a model of microbially induced hepatocarcinogenesis.
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Impact of CDT Toxin on Human DiseasesDynamic Duo-The Salmonella Cytolethal Distending Toxin Combines ADP-Ribosyltransferase and Nuclease Activities in a Novel Form of the Cytolethal Distending ToxinGut microbiota imbalance and colorectal cancerRelationship between intestinal microbiota and colorectal cancerBacterial Genotoxins: Merging the DNA Damage Response into Infection BiologyIntestinal microbiota composition of interleukin-10 deficient C57BL/6J mice and susceptibility to Helicobacter hepaticus-induced colitisHelicobacter hepaticus induces an inflammatory response in primary human hepatocytesThe Cytolethal Distending Toxin Contributes to Microbial Virulence and Disease Pathogenesis by Acting As a Tri-Perditious ToxinHeterogeneous Family of Cyclomodulins: Smart Weapons That Allow Bacteria to Hijack the Eukaryotic Cell Cycle and Promote Infections.Helicobacter hepaticus urease is not required for intestinal colonization but promotes hepatic inflammation in male A/JCr mice.The Cytolethal Distending Toxin Subunit CdtB of Helicobacter hepaticus Promotes Senescence and Endoreplication in Xenograft Mouse Models of Hepatic and Intestinal Cell Lines.The cytolethal distending toxin effects on Mammalian cells: a DNA damage perspective.Helicobacter hepaticus cholesterol-α-glucosyltransferase is essential for establishing colonization in male A/JCr mice.Helicobacter hepaticus infection promotes hepatitis and preneoplastic foci in farnesoid X receptor (FXR) deficient mice.Cytolethal distending toxin: a conserved bacterial genotoxin that blocks cell cycle progression, leading to apoptosis of a broad range of mammalian cell lineagesHelicobacter hepaticus--induced liver tumor promotion is associated with increased serum bile acid and a persistent microbial-induced immune response.Development of chitosan/heparin nanoparticle-encapsulated cytolethal distending toxin for gastric cancer therapy.Chemistry meets biology in colitis-associated carcinogenesisInflammation and colorectal cancer, when microbiota-host mutualism breaks.Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cellsCytolethal distending toxins require components of the ER-associated degradation pathway for host cell entry.Functional impacts of the intestinal microbiome in the pathogenesis of inflammatory bowel disease.Bacterial genotoxins promote inside-out integrin β1 activation, formation of focal adhesion complexes and cell spreading.What's the damage? The impact of pathogens on pathways that maintain host genome integrityThe Typhoid Toxin Promotes Host Survival and the Establishment of a Persistent Asymptomatic Infection.The struggle within: microbial influences on colorectal cancer.Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer.Identification of a genetic locus controlling bacteria-driven colitis and associated cancer through effects on innate inflammationGenetic susceptibility to chronic hepatitis is inherited codominantly in Helicobacter hepaticus-infected AB6F1 and B6AF1 hybrid male mice, and progression to hepatocellular carcinoma is linked to hepatic expression of lipogenic genes and immune funcHigh prevalence of mucosa-associated E. coli producing cyclomodulin and genotoxin in colon cancer.Genotoxicity of Cytolethal Distending Toxin (CDT) on Isogenic Human Colorectal Cell Lines: Potential Promoting Effects for Colorectal Carcinogenesis.Role of the Helicobacter hepaticus flagellar sigma factor FliA in gene regulation and murine colonizationMarked liver tumorigenesis by Helicobacter hepaticus requires perinatal exposure.Cytolethal distending toxin promotes Helicobacter cinaedi-associated typhlocolitis in interleukin-10-deficient mice.Bacterial genotoxins, gene methylation, and RNA interference: pointing to colorectal cancer as an infectious disease?Contribution of Helicobacter hepaticus cytolethal distending toxin subunits to human epithelial cell cycle arrest and apoptotic death in vitroCell resistance to the Cytolethal Distending Toxin involves an association of DNA repair mechanisms.The Cytolethal Distending Toxin Produced by Nontyphoidal Salmonella Serotypes Javiana, Montevideo, Oranienburg, and Mississippi Induces DNA Damage in a Manner Similar to That of Serotype Typhi.Genetic dysbiosis: the role of microbial insults in chronic inflammatory diseases.Hepatocellular carcinoma: prevalence and molecular pathogenesis of Helicobacter spp.
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P2860
Bacterial cytolethal distending toxin promotes the development of dysplasia in a model of microbially induced hepatocarcinogenesis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Bacterial cytolethal distendin ...... induced hepatocarcinogenesis.
@en
Bacterial cytolethal distendin ...... induced hepatocarcinogenesis.
@nl
type
label
Bacterial cytolethal distendin ...... induced hepatocarcinogenesis.
@en
Bacterial cytolethal distendin ...... induced hepatocarcinogenesis.
@nl
prefLabel
Bacterial cytolethal distendin ...... induced hepatocarcinogenesis.
@en
Bacterial cytolethal distendin ...... induced hepatocarcinogenesis.
@nl
P2093
P2860
P1476
Bacterial cytolethal distendin ...... y induced hepatocarcinogenesis
@en
P2093
Arlin B Rogers
Nancy S Taylor
P2860
P304
P356
10.1111/J.1462-5822.2007.00939.X
P577
2007-04-17T00:00:00Z