Analytical methods validation: bioavailability, bioequivalence and pharmacokinetic studies. Conference report.
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Results of single and repeat dose studies of the oral matrix metalloproteinase inhibitor marimastat in healthy male volunteersQuantitative biomarker analysis of synovial gene expression by real-time PCRHigh sensitivity assays for docetaxel and paclitaxel in plasma using solid-phase extraction and high-performance liquid chromatography with UV detection.Ribavirin Quantification in Combination Treatment of Chronic Hepatitis CSensitive and simultaneous determination of HIV protease inhibitors in rat biological samples by liquid chromatography-mass spectrometry.Retrospective data analysis and proposal of a practical acceptance criterion for inter-laboratory cross-validation of bioanalytical methods using liquid chromatography/tandem mass spectrometry.Pharmacokinetic and pharmacodynamic modeling of NN703, a growth hormone secretagogue, after a single po dose to human volunteers.Sevelamer hydrochloride (Renagel), a phosphate-binding polymer, does not alter the pharmacokinetics of two commonly used antihypertensives in healthy volunteers.Determination of quinapril and quinaprilat in human plasma by ultraperformance liquid chromatography-electrospray ionization mass spectrometry.Stereospecific high-performance liquid chromatography of taxifolin, applications in pharmacokinetics, and determination in tu fu ling (Rhizoma smilacis glabrae) and apple (Malus x domestica).Sensitive and rapid high-performance liquid chromatography tandem mass spectrometry method for estimation of fulvestrant in rabbit plasma.Stability: recommendation for best practices and harmonization from the Global Bioanalysis Consortium Harmonization TeamValidation and use of microdialysis for determination of pharmacokinetic properties of the chemotherapeutic agent mitomycin C - an experimental studyDevelopment and validation of a high-throughput and robust LC-MS/MS with electrospray ionization method for simultaneous quantitation of oseltamivir phosphate and its oseltamivir carboxylate metabolite in human plasma for pharmacokinetic studies.Glomerular filtration rate estimation using the Cockcroft-Gault and modification of diet in renal disease formulas for digoxin dose adjustment in patients with heart failure.Sirolimus and everolimus clearance in maintenance kidney and liver transplant recipients: diagnostic efficiency of the concentration/dose ratio for the prediction of trough steady-state concentrationsSelectivity in capillary electrokinetic separations.Issues on fit-for-purpose validation of a panel of ELISAs for application as biomarkers in clinical trials of anti-Angiogenic drugs.Sensitive bioassay for determination of fluconazole concentrations in plasma using a Candida albicans mutant hypersusceptible to azoles.A validated bioanalytical HPLC method for pharmacokinetic evaluation of 2-deoxyglucose in human plasma.A highly sensitive LC-tandem MS assay for the measurement in plasma and in urine of salbutamol administered by nebulization during mechanical ventilation in healthy volunteers.A pharmacodynamic study of sorafenib in patients with relapsed and refractory acute leukemiasPharmacokinetics of piperacillin-tazobactam in anuric intensive care patients during continuous venovenous hemodialysis.In vitro identification of the cytochrome P450 isozymes involved in the N-demethylation of the active opioid metabolite nortilidine to bisnortilidine.Multiplex ultra-performance liquid chromatography-tandem mass spectrometry method for simultaneous quantification in human plasma of fluconazole, itraconazole, hydroxyitraconazole, posaconazole, voriconazole, voriconazole-N-oxide, anidulafungin, andKA 672-HCl, a neuronal activator against dementia: tolerability, safety, and preliminary pharmacokinetics after single and multiple oral doses in healthy male and female volunteers.Pharmacokinetics of C-1027 in mice as determined by TCA-RA method.Pharmacokinetic application of a bio-analytical LC-MS method developed for 5-fluorouracil and methotrexate in mouse plasma, brain and urine.Influences on the pharmacokinetics of oxycodone: a multicentre cross-sectional study in 439 adult cancer patients.Formulation and bioequivalence of two valsartan tablets after a single oral administration.Pharmacokinetics and biodistribution of the cyclin-dependent kinase inhibitor -CR8- in mice.Tissue distribution and excretion of 125I-lidamycin in mice and rats.Metabolic activation and analgesic effect of flupirtine in healthy subjects, influence of the polymorphic NAT2, UGT1A1 and GSTP1.Measurement of estradiol, estrone, and testosterone in postmenopausal human serum by isotope dilution liquid chromatography tandem mass spectrometry without derivatization.The optimal dose of prophylactic intravenous naloxone in ameliorating opioid-induced side effects in children receiving intravenous patient-controlled analgesia morphine for moderate to severe pain: a dose finding study.QbD-oriented development and validation of a bioanalytical method for nevirapine with enhanced liquid-liquid extraction and chromatographic separation.Bioavailability of diclofenac potassium at low dosesA validated HPLC assay for the determination of R-(-)-gossypol in human plasma and its application in clinical pharmacokinetic studiesPopulation pharmacokinetic/pharmacodynamic (PK/PD) modelling of the hypothalamic-pituitary-gonadal axis following treatment with GnRH analogues.Effects of polymer molecular weight on relative oral bioavailability of curcumin.
P2860
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P2860
Analytical methods validation: bioavailability, bioequivalence and pharmacokinetic studies. Conference report.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh-hant
name
Analytical methods validation: ...... ic studies. Conference report.
@en
Analytical methods validation: ...... ic studies. Conference report.
@nl
type
label
Analytical methods validation: ...... ic studies. Conference report.
@en
Analytical methods validation: ...... ic studies. Conference report.
@nl
prefLabel
Analytical methods validation: ...... ic studies. Conference report.
@en
Analytical methods validation: ...... ic studies. Conference report.
@nl
P2093
P356
P1476
Analytical methods validation: ...... ic studies. Conference report.
@en
P2093
McDowall RD
McGilveray IJ
Viswanathan CT
P2888
P304
P356
10.1007/BF03189968
P577
1991-10-01T00:00:00Z