ICSBP directs bipotential myeloid progenitor cells to differentiate into mature macrophages.
about
P1343
The genetic association of variants in CD6, TNFRSF1A and IRF8 to multiple sclerosis: a multicenter case-control studyTIF1beta functions as a coactivator for C/EBPbeta and is required for induced differentiation in the myelomonocytic cell line U937IRF8 regulates acid ceramidase expression to mediate apoptosis and suppresses myelogeneous leukemiaTranscription factor IRF8 directs a silencing programme for TH17 cell differentiationCutting edge: IRF8 regulates Bax transcription in vivo in primary myeloid cellsICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cellsMonocytes in myocardial infarctionMolecular control of monocyte developmentMicroglia development and functionInterferon regulatory factor 8 (IRF8) interacts with the B cell lymphoma 6 (BCL6) corepressor BCORFunctional characterization of the human dendritic cell immunodeficiency associated with the IRF8(K108E) mutationInhibition of monocytic differentiation by phosphorylation-deficient Stat1 is associated with impaired expression of Stat2, ICSBP/IRF8 and C/EBPepsilonThe interferon consensus sequence-binding protein activates transcription of the gene encoding neurofibromin 1IRF-2 is involved in up-regulation of nonmuscle myosin heavy chain II-A gene expression during phorbol ester-induced promyelocytic HL-60 differentiationIRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathwaysDisabled-2 is transcriptionally regulated by ICSBP and augments macrophage spreading and adhesion.Innate immunity to intraphagosomal pathogens is mediated by interferon regulatory factor 8 (IRF-8) that stimulates the expression of macrophage-specific Nramp1 through antagonizing repression by c-MycA novel transactivating factor that regulates interferon-gamma-dependent gene expressionRunx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expressionInterferon regulatory factor-8 is important for histone deacetylase inhibitor-mediated antitumor activity.Cross-talk with myeloid accessory cells regulates human natural killer cell interferon-gamma responses to malaria.Interferon regulatory factor 8 mediates tumor-induced inhibition of antigen processing and presentation by dendritic cellsIRF8 regulates myeloid and B lymphoid lineage diversificationGene disruption study reveals a nonredundant role for TRIM21/Ro52 in NF-kappaB-dependent cytokine expression in fibroblastsInterferon consensus sequence-binding protein (ICSBP) promotes epithelial-to-mesenchymal transition (EMT)-like phenomena, cell-motility, and invasion via TGF-β signaling in U2OS cells.Blimp1-mediated repression of negative regulators is required for osteoclast differentiation.An intuitionistic approach to scoring DNA sequences against transcription factor binding site motifs.Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell developmentInnate immune regulation by STAT-mediated transcriptional mechanisms.Partner-regulated interaction of IFN regulatory factor 8 with chromatin visualized in live macrophages.CX3CR1+ CD8alpha+ dendritic cells are a steady-state population related to plasmacytoid dendritic cells.IRF8 is a critical transcription factor for transforming microglia into a reactive phenotypeInterferon regulatory factor-8-driven myeloid differentiation is regulated by 12/15-lipoxygenase-mediated redox signaling.Gamma interferon triggers interaction between ICSBP (IRF-8) and TEL, recruiting the histone deacetylase HDAC3 to the interferon-responsive element.Regulation and consequences of monocytosisIFN regulatory factor 8 is a key constitutive determinant of the morphological and molecular properties of microglia in the CNS.PU.1 and C/EBPalpha/beta convert fibroblasts into macrophage-like cellsIrf8-regulated genomic responses drive pathological inflammation during cerebral malaria.Transcription factor IRF8 plays a critical role in the development of murine basophils and mast cells.The prognostic significance of IRF8 transcripts in adult patients with acute myeloid leukemia
P2860
Q21560832-74882939-140C-4E97-B809-2A727698F587Q24600120-7B764AED-2D52-484A-9871-2552C436483CQ24613953-A6996DAE-E64F-409C-BF97-8403770C4306Q24616336-DA925EAA-6F5B-4EA1-8612-7D9C588FB557Q24634889-33DFA6CC-D407-4328-BC1E-F18CB86D6C9CQ24672345-8F049262-27C0-4DEA-AB4B-B785F8EF0CC6Q26827070-474228AE-B8C3-42C9-8A6F-CDDA7CF038F9Q27011850-C3E333A3-FDC3-49DE-86F1-B7C2F86564C3Q27316453-75EAB36F-B167-4C3B-90F8-B8B9550173D8Q28115493-6A7BF3F2-3C8E-449B-96D7-74A255A5959AQ28119180-0A41C978-F170-4737-A74B-8554F6FD86C9Q28258688-42493D35-26D6-474F-8045-7B9C75FBC030Q28282456-5C0533F8-1016-4A8F-8628-7D5F18CD0016Q28288871-35636C78-4054-48F3-8182-821C68F8AB9BQ28297876-22A1A558-26B4-49CA-AE63-DC23B3AC5B45Q28508344-A0416318-90B0-42EE-A724-DE365187A49AQ28588435-2810A9D3-AF64-4F68-AD6B-924BDF6A8865Q28588598-2370CD8B-52A7-4A57-80CD-7D9437C433DBQ30515139-8AFB2956-FF7E-4915-AFC7-FFBFF5060B5BQ31101656-400B3E53-BA4E-47FD-B350-3E125F0E9211Q33265885-BDC5114A-F063-4A2F-9C44-7E69E6AD3AA8Q33551366-697141CC-8133-49C7-B130-956FDD47EFA7Q33579478-DD7BD838-E8DF-42AE-A58B-37A493C83615Q33579495-045B166D-515A-4385-B7D4-E816CD3A3D1BQ33720109-F3796E67-A492-4263-BE39-42CE87595409Q33733731-AAA7A73C-CAEF-47EC-8491-D5A68FF56CD7Q33741178-7C115ABA-4363-48C7-98F0-D8D6D7F4F42AQ34049333-36C86B96-90C2-4EB7-BB68-F89266E4A3CBQ34055968-51BC1B3A-983C-4707-BF11-F64C55BD3D15Q34063504-0279F073-B705-420A-9F2A-3A1DF40C2A08Q34093092-45CDC322-6AD2-4626-B9CD-05288DD3CC81Q34154359-0104640F-0CB6-4976-97D4-F219EEA1EA0DQ34237964-B0C63ADB-B0AE-423F-9C8B-A226AD50724BQ34325633-5FE6E973-E525-43B3-AF6F-663C4CA69185Q34372534-8FE8885B-A52E-4715-90FD-E4AF7522DFBCQ34482817-51B02E89-FD8F-4F7D-BDB0-8B9129BBF05EQ34771857-7D53DBC3-FBEB-4649-8F86-3F02CD51D5FAQ34819713-2AD02B2E-6812-4B98-8DB9-0A6D37E1035AQ34876841-CA789918-0C27-4B1E-B291-6D062500DD4DQ34962889-114FE56E-6B05-479F-B644-53E0242E1421
P2860
ICSBP directs bipotential myeloid progenitor cells to differentiate into mature macrophages.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh-hant
name
ICSBP directs bipotential myel ...... tiate into mature macrophages.
@en
ICSBP directs bipotential myel ...... tiate into mature macrophages.
@nl
type
label
ICSBP directs bipotential myel ...... tiate into mature macrophages.
@en
ICSBP directs bipotential myel ...... tiate into mature macrophages.
@nl
prefLabel
ICSBP directs bipotential myel ...... tiate into mature macrophages.
@en
ICSBP directs bipotential myel ...... tiate into mature macrophages.
@nl
P2093
P1433
P1476
ICSBP directs bipotential myel ...... tiate into mature macrophages.
@en
P2093
Nagamura-Inoue T
Shmeltzer Z
P304
P356
10.1016/S1074-7613(00)00016-9
P407
P4510
P577
2000-08-01T00:00:00Z