Design, synthesis and evaluation of novel tacrine-rhein hybrids as multifunctional agents for the treatment of Alzheimer's disease.

Design, synthesis and evaluation of novel tacrine-rhein hybrids as multifunctional agents for the treatment of Alzheimer's disease.

Item
http://www.wikidata.org/entity/Q53458869
Recent development of multifunctional agents as potential drug candidates for the treatment of Alzheimer's disease.The molecular mechanism of rhein in diabetic nephropathy.Design, synthesis and multitarget biological profiling of second-generation anti-Alzheimer rhein-huprine hybrids.Recent progress in repositioning Alzheimer's disease drugs based on a multitarget strategy.Novel multitarget-directed tacrine derivatives as potential candidates for the treatment of Alzheimer's disease.Synthesis and bioevaluation of new tacrine-cinnamic acid hybrids as cholinesterase inhibitors against Alzheimer's disease.Multitarget Therapeutic Leads for Alzheimer's Disease: Quinolizidinyl Derivatives of Bi- and Tricyclic Systems as Dual Inhibitors of Cholinesterases and β-Amyloid (Aβ) Aggregation.Synthesis and pharmacological evaluation of donepezil-based agents as new cholinesterase/monoamine oxidase inhibitors for the potential application against Alzheimer's disease.Design, synthesis and evaluation of novel cinnamic acid derivatives bearing N-benzyl pyridinium moiety as multifunctional cholinesterase inhibitors for Alzheimer's disease.Naphthoquinone-Tryptophan Hybrid Inhibits Aggregation of the Tau-Derived Peptide PHF6 and Reduces Neurotoxicity.Facile access to functionalized indenes and fused quinolines by regioselective 5-enolexo-dig Michael addition and cyclization reactions.Diels-Alder and Formal Diels-Alder Cycloaddition Reactions of Ynamines and Ynamides
P2860

Design, synthesis and evaluation of novel tacrine-rhein hybrids as multifunctional agents for the treatment of Alzheimer's disease.

Item
http://www.wikidata.org/entity/Q53458869
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
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2013年學術文章
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2013年學術文章
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name
Design, synthesis and evaluati ...... atment of Alzheimer's disease.
@en
Design, synthesis and evaluati ...... atment of Alzheimer's disease.
@nl
type
label
Design, synthesis and evaluati ...... atment of Alzheimer's disease.
@en
Design, synthesis and evaluati ...... atment of Alzheimer's disease.
@nl
prefLabel
Design, synthesis and evaluati ...... atment of Alzheimer's disease.
@en
Design, synthesis and evaluati ...... atment of Alzheimer's disease.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P921
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P1433
P1476
Design, synthesis and evaluati ...... atment of Alzheimer's disease.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P921