Identification of CCAAT/enhancer-binding proteins as exchange protein activated by cAMP-activated transcription factors that mediate the induction of the SOCS-3 gene.
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C/EBPβ mediates growth hormone-regulated expression of multiple target genesSOCS3: An essential physiological inhibitor of signaling by interleukin-6 and G-CSF family cytokinesThe role of c-Jun in controlling the EPAC1-dependent induction of the SOCS3 gene in HUVECsGsα Deficiency in the Ventromedial Hypothalamus Enhances Leptin Sensitivity and Improves Glucose Homeostasis in Mice on a High-Fat Diet.Crosstalk between PKA and Epac regulates the phenotypic maturation and function of human dendritic cells.Pivotal advance: Kaposi's sarcoma-associated herpesvirus (KSHV)-encoded microRNA specifically induce IL-6 and IL-10 secretion by macrophages and monocytes.The cleaved cytoplasmic tail of polycystin-1 regulates Src-dependent STAT3 activation.Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsiosesThe future of EPAC-targeted therapies: agonism versus antagonismIdentification of a Novel, Small Molecule Partial Agonist for the Cyclic AMP Sensor, EPAC1.Prostaglandin E2-induced IL-23p19 subunit is regulated by cAMP-responsive element-binding protein and C/AATT enhancer-binding protein β in bone marrow-derived dendritic cellsGenomic analysis of the role of transcription factor C/EBPδ in the regulation of cell behaviour on nanometric groovesHexim1, a Novel Regulator of Leptin Function, Modulates Obesity and Glucose DisposalDistinct functions of CCAAT enhancer-binding protein isoforms in the regulation of manganese superoxide dismutase during interleukin-1beta stimulationFlavanoids induce expression of the suppressor of cytokine signalling 3 (SOCS3) gene and suppress IL-6-activated signal transducer and activator of transcription 3 (STAT3) activation in vascular endothelial cells.EPAC proteins transduce diverse cellular actions of cAMP.The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function.Epac2a-null mice exhibit obesity-prone nature more susceptible to leptin resistance.Regulation of the inflammatory response of vascular endothelial cells by EPAC1.Unbiased identification of substrates for the Epac1-inducible E3 ubiquitin ligase component SOCS-3.cAMP signalling in the vasculature: the role of Epac (exchange protein directly activated by cAMP).Characterization of the roles of suppressor of cytokine signaling-3 in prostate cancer development and progression.Neuroimmune interactions: dendritic cell modulation by the sympathetic nervous system.Epac1 increases migration of endothelial cells and melanoma cells via FGF2-mediated paracrine signaling.Suppressor of cytokine signaling-3 is a glucagon-inducible inhibitor of PKA activity and gluconeogenic gene expression in hepatocytes.Activation of protein kinase Calpha by EPAC1 is required for the ERK- and CCAAT/enhancer-binding protein beta-dependent induction of the SOCS-3 gene by cyclic AMP in COS1 cells.The protein kinase C inhibitor, Ro-31-7459, is a potent activator of ERK and JNK MAP kinases in HUVECs and yet inhibits cyclic AMP-stimulated SOCS-3 gene induction through inactivation of the transcription factor c-Jun.The Potential of a Novel Class of EPAC-Selective Agonists to Combat Cardiovascular Inflammation.Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability.Epac activation inhibits IL-6-induced cardiac myocyte dysfunction.Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling.Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.Exendin-4 inhibits high-altitude cerebral edema by protecting against neurobiological dysfunction.Differential PI3K signal transduction in obesity-associated cardiac hypertrophy and response to ischemia.
P2860
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P2860
Identification of CCAAT/enhancer-binding proteins as exchange protein activated by cAMP-activated transcription factors that mediate the induction of the SOCS-3 gene.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Identification of CCAAT/enhanc ...... induction of the SOCS-3 gene.
@en
Identification of CCAAT/enhanc ...... induction of the SOCS-3 gene.
@nl
type
label
Identification of CCAAT/enhanc ...... induction of the SOCS-3 gene.
@en
Identification of CCAAT/enhanc ...... induction of the SOCS-3 gene.
@nl
prefLabel
Identification of CCAAT/enhanc ...... induction of the SOCS-3 gene.
@en
Identification of CCAAT/enhanc ...... induction of the SOCS-3 gene.
@nl
P2093
P2860
P356
P1476
Identification of CCAAT/enhanc ...... induction of the SOCS-3 gene.
@en
P2093
Gillian Borland
Timothy M Palmer
William A Sands
P2860
P304
P356
10.1074/JBC.M710342200
P407
P577
2008-01-14T00:00:00Z