Binding of factor VIIa to the endothelial cell protein C receptor reduces its coagulant activity.
about
FVII, FVIIa, and downstream markers of extrinsic pathway activation differ by EPCR Ser219Gly variant in healthy menFactor VIIa interaction with endothelial cells and endothelial cell protein C receptor.Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) ConsortiumFactor VIIa binding to endothelial cell protein C receptor protects vascular barrier integrity in vivo.Endothelial cell protein C receptor: a multiliganded and multifunctional receptorInhibitory effects of oroxylin A on endothelial protein C receptor shedding in vitro and in vivo.Association of soluble endothelial protein C receptor plasma levels and PROCR rs867186 with cardiovascular risk factors and cardiovascular events in coronary artery disease patients: the Athero Gene study.Hemostatic markers are associated with the risk and prognosis of atrial fibrillation: the ARIC study.The endothelial protein C receptor supports tissue factor ternary coagulation initiation complex signaling through protease-activated receptors.Rab GTPases regulate endothelial cell protein C receptor-mediated endocytosis and trafficking of factor VIIaFactor VIIa bound to endothelial cell protein C receptor activates protease activated receptor-1 and mediates cell signaling and barrier protection.Coagulation factor Xa cleaves protease-activated receptor-1 and mediates signaling dependent on binding to the endothelial protein C receptor.Group V secretory phospholipase A2 impairs endothelial protein C receptor-dependent protein C activation and accelerates thrombosis in vivo.Inactivation of factor VIIa by antithrombin in vitro, ex vivo and in vivo: role of tissue factor and endothelial cell protein C receptor.Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery diseaseEndothelial cell protein C receptor-mediated redistribution and tissue-level accumulation of factor VIIa.Early rise in circulating endothelial protein C receptor correlates with poor outcome in severe sepsisHeterozygous congenital Factor VII deficiency with the 9729del4 mutation, associated with severe spontaneous intracranial bleeding in an adolescent maleFactor VIIa binding to endothelial cell protein C receptor.Mechanisms of anticoagulant and cytoprotective actions of the protein C pathway.Factor VIIa interaction with tissue factor and endothelial cell protein C receptor on cell surfaces.Lack of association of soluble endothelial protein C receptor and PROCR 6936A/G polymorphism with the risk of venous thromboembolism in a prospective study.The endothelial cell protein C receptor: cell surface conductor of cytoprotective coagulation factor signaling.A novel protein C-factor VII chimera provides new insights into the structural requirements for cytoprotective PAR1 signaling.Evaluation of procoagulant tissue factor expression in canine hemangiosarcoma cell lines.Targeting clotting proteins in cancer therapy - progress and challenges.Endothelial cell protein C receptor opposes mesothelioma growth driven by tissue factor.Should We Replace the Terms Intrinsic and Extrinsic Coagulation Pathways With Tissue Factor Pathway?Endothelial protein C receptor is required for tissue factor ternary complex signaling in the mouse.Influence of endothelial cell protein C receptor on plasma clearance of factor VIIa.Redistribution and hemostatic action of recombinant activated factor VII associated with platelets.EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growthBlockade of endothelial cell protein C receptor augments factor VIIa hemostatic effect in hemophilia treatment.Circulating endothelial cell protein C receptor: endothelial regulation and cumulative impact of gender and A3 haplotype.The endothelial protein C receptor enhances hemostasis of FVIIa administration in hemophilic mice in vivo.Factor X binding to endothelial cell protein C receptor: comparison with factor VIIa and activated protein C.Kinetic analysis and binding studies of a new recombinant human factor VIIa for treatment of haemophilia.Endothelial protein C receptor expression after cardiopulmonary bypass in adult cardiac surgical patients.Endothelial cell protein C receptor-dependent signaling.Emodin-6-O-β-D-glucoside down-regulates endothelial protein C receptor shedding.
P2860
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P2860
Binding of factor VIIa to the endothelial cell protein C receptor reduces its coagulant activity.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Binding of factor VIIa to the ...... educes its coagulant activity.
@en
Binding of factor VIIa to the ...... educes its coagulant activity.
@nl
type
label
Binding of factor VIIa to the ...... educes its coagulant activity.
@en
Binding of factor VIIa to the ...... educes its coagulant activity.
@nl
prefLabel
Binding of factor VIIa to the ...... educes its coagulant activity.
@en
Binding of factor VIIa to the ...... educes its coagulant activity.
@nl
P2093
P1476
Binding of factor VIIa to the ...... reduces its coagulant activity
@en
P2093
P304
P356
10.1111/J.1538-7836.2007.02648.X
P577
2007-09-01T00:00:00Z