ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death. - Wikidata - awgldk - TriplyDB

ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death.

ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death.

http://www.wikidata.org/entity/Q53572097

about

Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening Identification of SH3 domain proteins interacting with the cytoplasmic tail of the a disintegrin and metalloprotease 10 (ADAM10)The Janus Face of Death Receptor Signaling during Tumor Immunoediting Matrix metalloproteinases: regulators of the tumor microenvironment A Fas Ligand (FasL)-Fused Humanized Antibody Against Tumor-Associated Glycoprotein 72 Selectively Exhibits the Cytotoxic Effect Against Oral Cancer Cells with a Low FasL/Fas Ratio.TNF superfamily: a growing saga of kidney injury modulators.Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10 Many checkpoints on the road to cell death: regulation of Fas-FasL interactions and Fas signaling in peripheral immune responses.ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo.Retrovirally transduced murine T lymphocytes expressing FasL mediate effective killing of prostate cancer cells ADAM17 activity and other mechanisms of soluble L-selectin production during death receptor-induced leukocyte apoptosis.Full-length, membrane-anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF-kappaB pathway Targeting immune privilege to prevent pathogenic neovascularization Systemic autoimmunity and defective Fas ligand secretion in the absence of the Wiskott-Aldrich syndrome protein Pericellular proteolysis in cancer Increased synapse formation obtained by T cell epitopes containing a CxxC motif in flanking residues convert CD4+ T cells into cytolytic effectors.Autocrine IFNγ controls the regulatory function of lymphoproliferative double negative T cells Palmitoylation of human FasL modulates its cell death-inducing function Age-dependent changes in FasL (CD95L) modulate macrophage function in a model of age-related macular degeneration Differential surface expression of ADAM10 and ADAM17 on human T lymphocytes and tumor cells.Enzyme-instructed self-assembly: a multistep process for potential cancer therapy Fas death receptor signalling: roles of Bid and XIAP.Boyden Chamber Assay to Study of Cell Migration Induced by Metalloprotease Cleaved-CD95L.ERα signaling regulates MMP3 expression to induce FasL cleavage and osteoclast apoptosis.Dual role of immune cells in the testis: Protective or pathogenic for germ cells?Restimulation-induced apoptosis of T cells is impaired in patients with X-linked lymphoproliferative disease caused by SAP deficiency.The emergence of ADAM10 as a regulator of lymphocyte development and autoimmunity.The emerging role of matrix metalloproteases of the ADAM family in male germ cell apoptosis.Enzyme-Instructed Self-Assembly of Small D-Peptides as a Multiple-Step Process for Selectively Killing Cancer Cells.Resistance to anticancer immunity in cancer patients: potential strategies to reverse resistance.Gemcitabine sensitizes lung cancer cells to Fas/FasL system-mediated killing.A critical role for FcgammaRIIB in up-regulation of Fas ligand induced by a microbial polysaccharide.Posttranslational regulation of Fas ligand function.ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of vascular endothelial cadherin.The biological activity of FasL in human and mouse lungs is determined by the structure of its stalk region.Role of caspases in CD95-induced biphasic activation of acid sphingomyelinase.ADAM10, the rate-limiting protease of regulated intramembrane proteolysis of Notch and other proteins, is processed by ADAMS-9, ADAMS-15, and the gamma-secretase Membrane-bound Fas ligand only is essential for Fas-induced apoptosis The CD95 signaling pathway: To not die and fly.Overexpression of membrane-bound fas ligand (CD95L) exacerbates autoimmune disease and renal pathology in pristane-induced lupus.

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ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death.

http://www.wikidata.org/entity/Q53572097

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

@zh-my

2007年学术文章

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2007年學術文章

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2007年學術文章

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name

ADAM10 regulates FasL cell sur ...... activation-induced cell death.

@en

ADAM10 regulates FasL cell sur ...... activation-induced cell death.

@nl

type

label

ADAM10 regulates FasL cell sur ...... activation-induced cell death.

@en

ADAM10 regulates FasL cell sur ...... activation-induced cell death.

@nl

prefLabel

ADAM10 regulates FasL cell sur ...... activation-induced cell death.

@en

ADAM10 regulates FasL cell sur ...... activation-induced cell death.

@nl

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Cell Death & Differentiation

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ADAM10 regulates FasL cell sur ...... activation-induced cell death.

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B de Strooper

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D Hartmann

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K Reiss

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M Lettau

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M Schulte

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P Saftig

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P2860

The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion

The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts

Characterization of Fas (Apo-1, CD95)-Fas ligand interaction

Diacylglycerol kinase alpha regulates the secretion of lethal exosomes bearing Fas ligand during activation-induced cell death of T lymphocytes

Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family

ADAMs: key components in EGFR signalling and development

The cytoplasmic domain of Fas ligand costimulates TCR signals.

Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands

ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and beta-catenin translocation.

L1 is sequentially processed by two differently activated metalloproteases and presenilin/gamma-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowth

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1040-1049

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10.1038/SJ.CDD.4402101

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5

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14

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Thorsten Maretzky

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6515224

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