Regulation of ionizing radiation-induced apoptosis by mitochondrial NADP+-dependent isocitrate dehydrogenase.
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Concerted action of Nrf2-ARE pathway, MRN complex, HMGB1 and inflammatory cytokines - implication in modification of radiation damageStructural studies ofSaccharomyces cerevesiaemitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reactionRadioprotective effect of geraniin via the inhibition of apoptosis triggered by γ-radiation-induced oxidative stress.IDH1(R132H) mutation increases U87 glioma cell sensitivity to radiation therapy in hypoxia.Hoechst 33342 induced reactive oxygen species and impaired expression of cytochrome c oxidase subunit 1 leading to cell death in irradiated human cancer cells.Compensatory proteome adjustments imply tissue-specific structural and metabolic reorganization following episodic hypoxia or anoxia in the epaulette shark (Hemiscyllium ocellatum).Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolismProtective effects of sodium selenite supplementation against irradiation-induced damage in non-cancerous human esophageal cells.Overexpression of isocitrate dehydrogenase mutant proteins renders glioma cells more sensitive to radiation.What do we know about IDH1/2 mutations so far, and how do we use it?What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer.Long-term health effects of persistent exposure to low-dose lr192 gamma-raysProtective Effect of Fisetin (3,7,3',4'-Tetrahydroxyflavone) against γ-Irradiation-Induced Oxidative Stress and Cell Damage.Modulation of Radiation-Induced Genetic Damage by HCMV in Peripheral Blood Lymphocytes from a Brain Tumor Case-Control StudyEvaluation of hyperpolarized [1-¹³C]-pyruvate by magnetic resonance to detect ionizing radiation effects in real time.Increased sensitivity to radiochemotherapy in IDH1 mutant glioblastoma as demonstrated by serial quantitative MR volumetry.New insights into glioma classification based on isocitrate dehydrogenase 1 and 2 gene status.Role of isocitrate dehydrogenase in glioma.Glioblastoma Therapy Can Be Augmented by Targeting IDH1-Mediated NADPH Biosynthesis.IDH2 knockdown sensitizes tumor cells to emodin cytotoxicity in vitro and in vivo.An SOD mimic protects NADP+-dependent isocitrate dehydrogenase against oxidative inactivation.The Role of Mitochondrial NADPH-Dependent Isocitrate Dehydrogenase in Cancer Cells.Silencing of mitochondrial NADP+-dependent isocitrate dehydrogenase gene enhances selenite-induced apoptosis.Comparative analysis of renal protein expression in spontaneously hypertensive rat.Anti-apoptotic role of spermine against lead and/or gamma irradiation-induced hepatotoxicity in male rats.Idh2 Deficiency Exacerbates Acrolein-Induced Lung Injury through Mitochondrial Redox Environment Deterioration.A new functional IDH2 genetic variant is associated with the risk of lung cancer.IDH2 deficiency accelerates skin pigmentation in mice via enhancing melanogenesis.White light augments chemotherapeutic potential of cyclophosphamide: an in vitro study.Protective effect of Rehmannia glutinosa on the UV-induced apoptosis in U937 cells.
P2860
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P2860
Regulation of ionizing radiation-induced apoptosis by mitochondrial NADP+-dependent isocitrate dehydrogenase.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Regulation of ionizing radiati ...... dent isocitrate dehydrogenase.
@en
Regulation of ionizing radiati ...... dent isocitrate dehydrogenase.
@nl
type
label
Regulation of ionizing radiati ...... dent isocitrate dehydrogenase.
@en
Regulation of ionizing radiati ...... dent isocitrate dehydrogenase.
@nl
prefLabel
Regulation of ionizing radiati ...... dent isocitrate dehydrogenase.
@en
Regulation of ionizing radiati ...... dent isocitrate dehydrogenase.
@nl
P2093
P2860
P356
P1476
Regulation of ionizing radiati ...... dent isocitrate dehydrogenase.
@en
P2093
In Sup Kil
Jeen-Woo Park
Jin Hyup Lee
Sung Youl Kim
P2860
P304
13385-13394
P356
10.1074/JBC.M700303200
P407
P577
2007-03-09T00:00:00Z