Combined effects of the two reciprocal t(4;11) fusion proteins MLL.AF4 and AF4.MLL confer resistance to apoptosis, cell cycling capacity and growth transformation.

Combined effects of the two reciprocal t(4;11) fusion proteins MLL.AF4 and AF4.MLL confer resistance to apoptosis, cell cycling capacity and growth transformation.

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http://www.wikidata.org/entity/Q53586148
miR-128b is a potent glucocorticoid sensitizer in MLL-AF4 acute lymphocytic leukemia cells and exerts cooperative effects with miR-221Systematic Classification of Mixed-Lineage Leukemia Fusion Partners Predicts Additional Cancer PathwaysA novel mutation in the miR-128b gene reduces miRNA processing and leads to glucocorticoid resistance of MLL-AF4 acute lymphocytic leukemia cells.Identification of genes transcriptionally responsive to the loss of MLL fusions in MLL-rearranged acute lymphoblastic leukemia.Molecular targeting of MLL-rearranged leukemia cell lines with the synthetic peptide PFWT synergistically enhances the cytotoxic effect of established chemotherapeutic agents.MLL-Rearranged Leukemias-An Update on Science and Clinical Approaches.Mixed lineage leukemia: roles in human malignancies and potential therapy.Insights into the cellular origin and etiology of the infant pro-B acute lymphoblastic leukemia with MLL-AF4 rearrangement.The versatile landscape of haematopoiesis: are leukaemia stem cells as versatile?MLL leukemia and future treatment strategies.Cell-based analysis of structure-function activity of threonine aspartase 1Transcriptional properties of human NANOG1 and NANOG2 in acute leukemic cells.Expression of MLL-AF4 or AF4-MLL fusions does not impact the efficiency of DNA damage repair.AF4 and AF4-MLL mediate transcriptional elongation of 5-lipoxygenase mRNA by 1, 25-dihydroxyvitamin D3Inhibition of class I HDACs abrogates the dominant effect of MLL-AF4 by activation of wild-type MLL.OCT4 pseudogenes present in human leukemia cells.The leukemogenic AF4-MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures.
P2860

Combined effects of the two reciprocal t(4;11) fusion proteins MLL.AF4 and AF4.MLL confer resistance to apoptosis, cell cycling capacity and growth transformation.

Item
http://www.wikidata.org/entity/Q53586148
description
2006 nî lūn-bûn
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2006年の論文
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Combined effects of the two re ...... ity and growth transformation.
@en
Combined effects of the two re ...... ity and growth transformation.
@nl
type
label
Combined effects of the two re ...... ity and growth transformation.
@en
Combined effects of the two re ...... ity and growth transformation.
@nl
prefLabel
Combined effects of the two re ...... ity and growth transformation.
@en
Combined effects of the two re ...... ity and growth transformation.
@nl
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Combined effects of the two re ...... ity and growth transformation.
@en
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698