Branchio-oto-renal syndrome associated mutations in Eyes Absent 1 result in loss of phosphatase activity.
about
Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absentCrystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factorStructure-function analyses of the human SIX1–EYA2 complex reveal insights into metastasis and BOR syndromeThe EYA tyrosine phosphatase activity is pro-angiogenic and is inhibited by benzbromaroneEYA1 mutations associated with the branchio-oto-renal syndrome result in defective otic development in Xenopus laevisThe Eyes Absent phosphatase-transactivator proteins promote proliferation, transformation, migration, and invasion of tumor cellsEyes absent tyrosine phosphatase activity is not required for Drosophila development or survivalBOR-syndrome-associated Eya1 mutations lead to enhanced proteasomal degradation of Eya1 proteinThe SIX1-EYA transcriptional complex as a therapeutic target in cancer.The Eyes Absent proteins in development and disease.Branchio-oto-renal syndrome (BOR): novel mutations in the EYA1 gene, and a review of the mutational genetics of BOR.Interactions with the Abelson tyrosine kinase reveal compartmentalization of eyes absent function between nucleus and cytoplasm.The EYA-SO/SIX complex in development and disease.The canonical wnt signal restricts the glycogen synthase kinase 3/fbw7-dependent ubiquitination and degradation of eya1 phosphatase.In Silico Analyses Reveal the Relationship Between SIX1/EYA1 Mutations and Conotruncal Heart Defects.
P2860
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P2860
Branchio-oto-renal syndrome associated mutations in Eyes Absent 1 result in loss of phosphatase activity.
description
2006 nî lūn-bûn
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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name
Branchio-oto-renal syndrome as ...... loss of phosphatase activity.
@en
Branchio-oto-renal syndrome as ...... loss of phosphatase activity.
@nl
type
label
Branchio-oto-renal syndrome as ...... loss of phosphatase activity.
@en
Branchio-oto-renal syndrome as ...... loss of phosphatase activity.
@nl
prefLabel
Branchio-oto-renal syndrome as ...... loss of phosphatase activity.
@en
Branchio-oto-renal syndrome as ...... loss of phosphatase activity.
@nl
P2860
P1433
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Branchio-oto-renal syndrome as ...... loss of phosphatase activity.
@en
P2093
Jayanagendra P Rayapureddi
Rashmi S Hegde
P2860
P304
P356
10.1016/J.FEBSLET.2006.06.009
P407
P577
2006-06-15T00:00:00Z