Selective inhibition of Rab prenylation by a phosphonocarboxylate analogue of risedronate induces apoptosis, but not S-phase arrest, in human myeloma cells.

Selective inhibition of Rab prenylation by a phosphonocarboxylate analogue of risedronate induces apoptosis, but not S-phase arrest, in human myeloma cells.

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http://www.wikidata.org/entity/Q53627280
Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylationGenes associated with the tumour microenvironment are differentially expressed in cured versus primary chemotherapy-refractory diffuse large B-cell lymphomaProteomic analysis of protein expression in human tonsillar cancer: differentially expressed proteins characterize human tonsillar cancer.Osteoclasts in multiple myeloma are derived from Gr-1+CD11b+myeloid-derived suppressor cells.Fluorescent risedronate analogues reveal bisphosphonate uptake by bone marrow monocytes and localization around osteocytes in vivoThe role of bisphosphonates in multiple myeloma: mechanisms, side effects, and the future.Novel functions for Rab GTPases in multiple aspects of tumour progression.Onco-Golgi: Is Fragmentation a Gate to Cancer Progression?Choosing a treatment for patients at the time a fracture is presented.Bisphosphonates as antimyeloma drugs.Zoledronic acid induces apoptosis and S-phase arrest in mesothelioma through inhibiting Rab family proteins and topoisomerase II actions.Isoprenoid biosynthetic pathway inhibition disrupts monoclonal protein secretion and induces the unfolded protein response pathway in multiple myeloma cells.Differential activities of thalidomide and isoprenoid biosynthetic pathway inhibitors in multiple myeloma cells.The bisphosphonate zoledronic acid decreases tumor growth in bone in mice with defective osteoclasts.Apomine enhances the antitumor effects of lovastatin on myeloma cells by down-regulating 3-hydroxy-3-methylglutaryl-coenzyme A reductase.Structure of the disordered C terminus of Rab7 GTPase induced by binding to the Rab geranylgeranyl transferase catalytic complex reveals the mechanism of Rab prenylation.Pseudomonas aeruginosa ExoS Induces Intrinsic Apoptosis in Target Host Cells in a Manner That is Dependent on its GAP Domain Activity
P2860

Selective inhibition of Rab prenylation by a phosphonocarboxylate analogue of risedronate induces apoptosis, but not S-phase arrest, in human myeloma cells.

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http://www.wikidata.org/entity/Q53627280
description
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name
Selective inhibition of Rab pr ...... rrest, in human myeloma cells.
@en
Selective inhibition of Rab pr ...... rrest, in human myeloma cells.
@nl
type
label
Selective inhibition of Rab pr ...... rrest, in human myeloma cells.
@en
Selective inhibition of Rab pr ...... rrest, in human myeloma cells.
@nl
prefLabel
Selective inhibition of Rab pr ...... rrest, in human myeloma cells.
@en
Selective inhibition of Rab pr ...... rrest, in human myeloma cells.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Selective inhibition of Rab pr ...... arrest, in human myeloma cells
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698