Selective inhibition of Rab prenylation by a phosphonocarboxylate analogue of risedronate induces apoptosis, but not S-phase arrest, in human myeloma cells.
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Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylationGenes associated with the tumour microenvironment are differentially expressed in cured versus primary chemotherapy-refractory diffuse large B-cell lymphomaProteomic analysis of protein expression in human tonsillar cancer: differentially expressed proteins characterize human tonsillar cancer.Osteoclasts in multiple myeloma are derived from Gr-1+CD11b+myeloid-derived suppressor cells.Fluorescent risedronate analogues reveal bisphosphonate uptake by bone marrow monocytes and localization around osteocytes in vivoThe role of bisphosphonates in multiple myeloma: mechanisms, side effects, and the future.Novel functions for Rab GTPases in multiple aspects of tumour progression.Onco-Golgi: Is Fragmentation a Gate to Cancer Progression?Choosing a treatment for patients at the time a fracture is presented.Bisphosphonates as antimyeloma drugs.Zoledronic acid induces apoptosis and S-phase arrest in mesothelioma through inhibiting Rab family proteins and topoisomerase II actions.Isoprenoid biosynthetic pathway inhibition disrupts monoclonal protein secretion and induces the unfolded protein response pathway in multiple myeloma cells.Differential activities of thalidomide and isoprenoid biosynthetic pathway inhibitors in multiple myeloma cells.The bisphosphonate zoledronic acid decreases tumor growth in bone in mice with defective osteoclasts.Apomine enhances the antitumor effects of lovastatin on myeloma cells by down-regulating 3-hydroxy-3-methylglutaryl-coenzyme A reductase.Structure of the disordered C terminus of Rab7 GTPase induced by binding to the Rab geranylgeranyl transferase catalytic complex reveals the mechanism of Rab prenylation.Pseudomonas aeruginosa ExoS Induces Intrinsic Apoptosis in Target Host Cells in a Manner That is Dependent on its GAP Domain Activity
P2860
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P2860
Selective inhibition of Rab prenylation by a phosphonocarboxylate analogue of risedronate induces apoptosis, but not S-phase arrest, in human myeloma cells.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
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2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
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2006年學術文章
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name
Selective inhibition of Rab pr ...... rrest, in human myeloma cells.
@en
Selective inhibition of Rab pr ...... rrest, in human myeloma cells.
@nl
type
label
Selective inhibition of Rab pr ...... rrest, in human myeloma cells.
@en
Selective inhibition of Rab pr ...... rrest, in human myeloma cells.
@nl
prefLabel
Selective inhibition of Rab pr ...... rrest, in human myeloma cells.
@en
Selective inhibition of Rab pr ...... rrest, in human myeloma cells.
@nl
P2093
P356
P1476
Selective inhibition of Rab pr ...... arrest, in human myeloma cells
@en
P2093
Anke J Roelofs
Annemieke Meijer
Claire M Shipman
Frank H Ebetino
P304
P356
10.1002/IJC.21977
P577
2006-09-01T00:00:00Z