The clinical potential for koff-rate measurement in adoptive immunotherapy.

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Identifying Individual T Cell Receptors of Optimal Avidity for Tumor Antigens Generation of high-avidity, WT1-reactive CD8+ cytotoxic T cell clones with anti-leukemic activity by streptamer technology.

P2860

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The clinical potential for koff-rate measurement in adoptive immunotherapy.

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http://www.wikidata.org/entity/Q53673922

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2013 nî lūn-bûn

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2013年の論文

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2013年学术文章

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2013年学术文章

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2013年学术文章

@zh-cn

2013年学术文章

@zh-hans

2013年学术文章

@zh-my

2013年学术文章

@zh-sg

2013年學術文章

@yue

2013年學術文章

@zh-hant

name

The clinical potential for koff-rate measurement in adoptive immunotherapy.

@en

The clinical potential for koff-rate measurement in adoptive immunotherapy.

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type

Item

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The clinical potential for koff-rate measurement in adoptive immunotherapy.

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The clinical potential for koff-rate measurement in adoptive immunotherapy.

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The clinical potential for koff-rate measurement in adoptive immunotherapy.

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The clinical potential for koff-rate measurement in adoptive immunotherapy.

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P1476

The clinical potential for koff-rate measurement in adoptive immunotherapy.

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Bianca Weissbrich

http://www.w3.org/2001/XMLSchema#string

Dirk H Busch

http://www.w3.org/2001/XMLSchema#string

Magdalena Nauerth

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P2860

Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia

Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1

TCR-ligand koff rate correlates with the protective capacity of antigen-specific CD8+ T cells for adoptive transfer.

TCRs with high affinity for foreign pMHC show self-reactivity.

High-affinity TCRs generated by phage display provide CD4+ T cells with the ability to recognize and kill tumor cell lines.

Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time.

Interplay between T cell receptor binding kinetics and the level of cognate peptide presented by major histocompatibility complexes governs CD8+ T cell responsiveness.

SHP-1 phosphatase activity counteracts increased T cell receptor affinity.

Single and dual amino acid substitutions in TCR CDRs can enhance antigen-specific T cell functions.

Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma.

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1151-1153

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scholarly article

editorial

P356

10.1586/1744666X.2013.855609

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P478

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2013-12-01T00:00:00Z

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P698

24215403

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P921

immunotherapy

The clinical potential for koff-rate measurement in adoptive immunotherapy.

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P2860

P2860

The clinical potential for koff-rate measurement in adoptive immunotherapy.

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P1476

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P921