about
How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological functionActivation by Allostery in Cell-Wall Remodeling by a Modular Membrane-Bound Lytic Transglycosylase from Pseudomonas aeruginosaEndless Resistance. Endless Antibiotics?Matrix metalloproteinase 2 inhibition: combined quantum mechanics and molecular mechanics studies of the inhibition mechanism of (4-phenoxyphenylsulfonyl)methylthiirane and its oxirane analogue.DFT studies of the ring-opening mechanism of SB-3CT, a potent inhibitor of matrix metalloproteinase 2.Matrix metalloproteinase 2 (MMP2) inhibition: DFT and QM/MM studies of the deprotonation-initialized ring-opening reaction of the sulfoxide analogue of SB-3CT.Elucidation of the structure of the membrane anchor of penicillin-binding protein 5 of Escherichia coliBacterial resistance to beta-lactam antibiotics: compelling opportunism, compelling opportunity.Host-guest chemistry of the peptidoglycanThe sentinel role of peptidoglycan recycling in the β-lactam resistance of the Gram-negative Enterobacteriaceae and Pseudomonas aeruginosa.Exploration of mild copper-mediated coupling of organotrifluoroborates in the synthesis of thiirane-based inhibitors of matrix metalloproteinasesConformational analyses of thiirane-based gelatinase inhibitorsBeta-lactam resistance in Staphylococcus aureus: the adaptive resistance of a plastic genome.Synthesis and NMR characterization of (Z,Z,Z,Z,E,E,ω)-heptaprenol.The Tipper-Strominger Hypothesis and Triggering of Allostery in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus (MRSA).Molecular basis and phenotype of methicillin resistance in Staphylococcus aureus and insights into new beta-lactams that meet the challenge.Inhibition of histone deacetylases: a pharmacological approach to the treatment of non-cancer disorders.Three decades of the class A beta-lactamase acyl-enzyme.Mechanism-based profiling of MMPs.The future of the β-lactams.Epidemiological expansion, structural studies, and clinical challenges of new β-lactamases from gram-negative bacteria.Bacterial cell-wall recycling.β-Lactam Resistance Mechanisms: Gram-Positive Bacteria and Mycobacterium tuberculosis.Reductive drug metabolism.Protonation states of active-site lysines of penicillin-binding protein 6 from Escherichia coli and the mechanistic implications.A computational evaluation of the mechanism of penicillin-binding protein-catalyzed cross-linking of the bacterial cell wallInvestigation of the mechanism of the cell wall DD-carboxypeptidase reaction of penicillin-binding protein 5 of Escherichia coli by quantum mechanics/molecular mechanics calculations.Ab initio QM/MM study of class A beta-lactamase acylation: dual participation of Glu166 and Lys73 in a concerted base promotion of Ser70.Molecular structures and dynamics of the stepwise activation mechanism of a matrix metalloproteinase zymogen: challenging the cysteine switch dogma.Synthesis and shift-reagent-assisted full NMR assignment of bacterial (Z8,E2,ω)-undecaprenol.Total Syntheses of Bulgecins A, B, and C and Their Bactericidal Potentiation of the β-Lactam Antibiotics.Peptide to glycopeptide: glycosylated oligopeptide renin inhibitors with attenuated in vivo clearance propertiesKinetics and inhibition of lipid exchange catalyzed by plasma cholesteryl ester transfer protein (lipid transfer protein)Method for measuring the activities of cholesteryl ester transfer protein (lipid transfer protein)Noncovalent binding of a mitomycin C metabolite, 2,7-diaminomitosene, to duplex DNAAppraisal of a glycopeptide cloaking strategy for a therapeutic oligopeptide: glycopeptide analogs of the renin inhibitor ditekirenA convenient synthesis of 7 alpha-hydroxycholest-4-en-3-one by the hydroxypropyl-beta-cyclodextrin-facilitated cholesterol oxidase oxidation of 3 beta,7 alpha-cholest-5-ene-3,7-diolA Mechanistic Study of the Dihydroflavin Reductive Cleavage of the Dihydroflavin-Tetrahydronaphthalene Epoxide AdductsRegioselective Control of the SNAr Amination of 5-Substituted-2,4-Dichloropyrimidines Using Tertiary Amine NucleophilesEnsemble of Pinanones from the Permanganate Oxidation of Myrtenal
P50
Q27680124-C23627D9-BD16-4816-BB03-5EE8C649771DQ27728048-AAB86B5F-0E4A-4E38-A4C8-E10ED98E1ECAQ28822179-F1C8E5A6-5698-48A9-9D71-D2E5AB0B1CDDQ33638905-E243D7BD-21F6-4C37-9657-F9465BB884B0Q33650054-2D571E77-8D35-428A-8051-F8003C0EB4EDQ33652126-1D704EB8-8D63-48A9-A07F-0952706A9953Q33821568-BAD7C6FF-8D61-4533-9336-B1874E7E8162Q33984936-FC485F7A-B987-40B6-9472-0E2FB1B8040AQ34013593-493DFD08-FC02-48E3-8233-325F2B2466E0Q34167642-B232225F-13D1-4554-A02E-28BAF855BE04Q34851893-D441BC87-489A-4B13-905B-B08EDFC2F310Q35777953-598AC432-43E2-48DD-AD16-AEE8AAFFBE5BQ36249578-10F824E2-912E-4348-856A-620F8B56BDA1Q36311758-513BBA85-0F37-4231-BF21-CA9B762E1230Q36392365-37495932-597F-4E8A-9530-B967527D63E1Q37392891-49DF7C5D-EE1B-4C1F-B46B-A34F8617F491Q37438513-2E7F14B5-CDF4-4126-B363-A612F20FD4DCQ37524130-F4A36FC7-F6B7-478A-A09A-DDE8CB288BCDQ37687929-D3F7BE06-E2E1-4475-9B3F-D24786F500C1Q37796156-7CA65C46-171F-4774-89DE-17CA53C6BFAFQ37899179-E1DCD04C-D9C3-46C9-943A-06B47F6A56EAQ38060821-09A55BB9-C16E-4345-B665-86DF1C3E02F1Q38811605-BD3CCEE2-DD6C-4C09-9FF5-FF311E1F94BAQ40157895-44322B90-5405-469E-898A-CB660DE731E1Q40696079-49B59C9A-8C50-4C86-A891-80911A12C134Q42156467-9A2E4A7F-990F-4A86-8FE2-2E79376AA166Q46521368-2D1BA1C1-9026-443E-8E88-CFFBC338EDDEQ46785331-022E0834-8531-4E5F-8DC0-D54D09F3AACFQ46955394-3686A84C-364C-477C-B64C-7A2434817CF9Q50006969-8DA276FB-EB8F-402B-BB69-99B129FC3C07Q55398522-6A4030FC-DEFB-402F-9988-969B03D1C7CCQ68014162-FE8ED318-14CD-4CA4-A7AB-43798693FE3DQ71715446-DB684ED4-3A7F-4EB6-8878-9A6AADD0EB51Q71807016-DF09D2D5-2330-4104-B59B-A5A223C5F29FQ72207842-4258C7CD-C6DB-4551-8208-3040E714641CQ72329995-92C0995C-6645-42C7-B74D-0E9346C04FA3Q72339141-60363803-04D5-4476-B146-406D9FD9DCBBQ74070666-60F1EAE5-5EAB-4B6F-968F-B3A5DAE7478AQ85556790-6BD280CB-CD3E-4DC3-8C15-1A426B82AE14Q87626990-9954D3F0-EEB7-4936-84A5-9361201943A4
P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Jed F Fisher
@nl
Jed F Fisher
@sl
Jed F. Fisher
@en
Jed F. Fisher
@es
type
label
Jed F Fisher
@nl
Jed F Fisher
@sl
Jed F. Fisher
@en
Jed F. Fisher
@es
prefLabel
Jed F Fisher
@nl
Jed F Fisher
@sl
Jed F. Fisher
@en
Jed F. Fisher
@es
P106
P1153
7404017627
P31
P496
0000-0002-7174-4352