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Treatment of hippocampal neurons with cyclosporin A results in calcium overload and apoptosis which are independent on NMDA receptor activationChanges of the trans-activating potential of AP-1 transcription factor during cyclosporin A-induced apoptosis of glioma cells are mediated by phosphorylation and alterations of AP-1 compositionCyclosporin A-sensitive signaling pathway involving calcineurin regulates survival of reactive astrocytes.Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway.Modulation of the composition of AP-1 complex and its impact on transcriptional activity.P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3.Inhibitors of SRC kinases impair antitumor activity of anti-CD20 monoclonal antibodies.Multifunctional protein APPL2 contributes to survival of human glioma cells.Endocytic proteins in the regulation of nuclear signaling, transcription and tumorigenesis.Functional characterization of the interactions between endosomal adaptor protein APPL1 and the NuRD co-repressor complex.Proteomic identification of the wt-p53-regulated tumor cell secretome.Inhibition of Akt kinase signalling and activation of Forkhead are indispensable for upregulation of FasL expression in apoptosis of glioma cells.Tumor suppressor p53 mediates apoptotic cell death triggered by cyclosporin A.P14ARF suppresses tumor-induced thrombosis by regulating the tissue factor pathway.APPL1 regulates basal NF-κB activity by stabilizing NIK.Sorafenib improves rituximab and ofatumumab efficacy by decreasing the expression of complement regulatory proteinsTRAIL triggers apoptosis in human malignant glioma cells through extrinsic and intrinsic pathways.Dissection of CD20 regulation in lymphoma using RNAi.HDAC6 inhibition upregulates CD20 levels and increases the efficacy of anti-CD20 monoclonal antibodies.Nuclear factor of activated T cells (NFAT) as a new component of the signal transduction pathway in glioma cells.Mouse oocytes penetrated by sperm at GV or GVBD stage lose the ability to fuse with additional spermatozoa.FOXO1 promotes resistance of non-Hodgkin lymphomas to anti-CD20-based therapy.B-cell receptor pathway inhibitors affect CD20 levels and impair antitumor activity of anti-CD20 monoclonal antibodiesAbstract 3845: Endocytic protein APPL2 as a regulator of glioblastoma cell growthSyk kinase, tyrosine-phosphorylated proteins and actin filaments accumulate at forming phagosomes during Fcgamma receptor-mediated phagocytosis[The role of MAP kinases and inducible transcription factors in the regulation of cell death and survival]Impaired AP-1 dimers and NFAT complex formation in immature thymocytes during in vivo glucocorticoid-induced apoptosisCholesterol restricts lymphotoxin β receptor-triggered NF-κB signalingInhibition of SYK or BTK augments venetoclax sensitivity in SHP1-negative/BCL-2-positive diffuse large B-cell lymphoma
P50
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P50
description
Pools onderzoekster
@nl
hulumtuese
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polska biolog molekularna
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researcher
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ricercatrice
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հետազոտող
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name
Beata Pyrzynska
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Beata Pyrzynska
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Beata Pyrzynska
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Beata Pyrzynska
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Beata Pyrzynska
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Beata Pyrzyńska
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Beata Pyrzyńska
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Beata Pyrzyńska
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Beata Pyrzyńska
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Beata Pyrzyńska
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type
label
Beata Pyrzynska
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Beata Pyrzynska
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Beata Pyrzynska
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Beata Pyrzynska
@nl
Beata Pyrzynska
@sl
Beata Pyrzyńska
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Beata Pyrzyńska
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Beata Pyrzyńska
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Beata Pyrzyńska
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Beata Pyrzyńska
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prefLabel
Beata Pyrzynska
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Beata Pyrzynska
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Beata Pyrzynska
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Beata Pyrzynska
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Beata Pyrzynska
@sl
Beata Pyrzyńska
@ca
Beata Pyrzyńska
@cs
Beata Pyrzyńska
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Beata Pyrzyńska
@hr
Beata Pyrzyńska
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P1053
T-2187-2018
P1153
6602427358
P1412
P1559
Beata Pyrzyńska
@pl
P21
P214
92145066490366591843
P27
P31
P3124
P496
0000-0002-0490-618X
P735
P7859
viaf-92145066490366591843