Single-nucleotide polymorphism (SNP) analysis in the ABC half-transporter ABCG2 (MXR/BCRP/ABCP1).
about
Expression levels of the ABCG2 multidrug transporter in human erythrocytes correspond to pharmacologically relevant genetic variationsDeterminants of the activity and substrate recognition of breast cancer resistance protein (ABCG2).ABCG2 (BCRP) expression in normal and malignant hematopoietic cells.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.Structure and function of the human breast cancer resistance protein (BCRP/ABCG2).Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters.ABCG2 expression, function, and promoter methylation in human multiple myelomaMechanisms of resistance to anticancer drugs: the role of the polymorphic ABC transporters ABCB1 and ABCG2.Role of the breast cancer resistance protein (ABCG2) in drug transport.Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications.Breast cancer resistance protein in pharmacokinetics and drug-drug interactions.Human ABC transporter ABCG2 in xenobiotic protection and redox biology.BCRP/ABCG2 in the placenta: expression, function and regulation.Transporters in the intestine limiting drug and toxin absorption.Pharmacogenomics in colorectal cancer: the first step for individualized-therapyThe emerging importance of transporter proteins in the psychopharmacological treatment of the pregnant patient.The 315-316 deletion determines the BXP-21 antibody epitope but has no effect on the function of wild type ABCG2 or the Q141K variant.Overlapping substrate and inhibitor specificity of human and murine ABCG2.Identification of compounds that correlate with ABCG2 transporter function in the National Cancer Institute Anticancer Drug Screen.Transporter pharmacogenetics: transporter polymorphisms affect normal physiology, diseases, and pharmacotherapyThe ABCG2 transporter and its relations with the pharmacokinetics, drug interaction and lipid-lowering effects of statins.Variation and evolution of the ABC transporter genes ABCB1, ABCC1, ABCG2, ABCG5 and ABCG8: implication for pharmacogenetics and disease.Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expression.Human ABCG2: structure, function, and its role in multidrug resistance.Human ABC transporter ABCG2/BCRP expression in chemoresistance: basic and clinical perspectives for molecular cancer therapeutics.Structure and function of BCRP, a broad specificity transporter of xenobiotics and endobiotics.Cloning, mapping and association studies of the ovine ABCG2 gene with facial eczema disease in sheep.The identification of two germ-line mutations in the human breast cancer resistance protein gene that result in the expression of a low/non-functional protein.A pharmacogenetic study of docetaxel and thalidomide in patients with castration-resistant prostate cancer using the DMET genotyping platform.Influence of multidrug resistance and drug transport proteins on chemotherapy drug metabolism.Impact of Transporter Polymorphisms on Drug Development: Is It Clinically Significant?Major SNP (Q141K) variant of human ABC transporter ABCG2 undergoes lysosomal and proteasomal degradationsATP-binding cassette transporter G2 mediates the efflux of phototoxins on the luminal membrane of retinal capillary endothelial cells.Reversal of breast cancer resistance protein-mediated drug resistance by tryprostatin A.Metabolic Interactions of Purine Derivatives with Human ABC Transporter ABCG2: Genetic Testing to Assess Gout RiskSingle nucleotide polymorphisms result in impaired membrane localization and reduced atpase activity in multidrug transporter ABCG2.ABCG2 Q141K polymorphism is associated with chemotherapy-induced diarrhea in patients with diffuse large B-cell lymphoma who received frontline rituximab plus cyclophosphamide/doxorubicin/vincristine/prednisone chemotherapy.Pharmacogenomics of the human ABC transporter ABCG2: from functional evaluation to drug molecular design.
P2860
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P2860
Single-nucleotide polymorphism (SNP) analysis in the ABC half-transporter ABCG2 (MXR/BCRP/ABCP1).
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Single-nucleotide polymorphism ...... porter ABCG2 (MXR/BCRP/ABCP1).
@en
type
label
Single-nucleotide polymorphism ...... porter ABCG2 (MXR/BCRP/ABCP1).
@en
prefLabel
Single-nucleotide polymorphism ...... porter ABCG2 (MXR/BCRP/ABCP1).
@en
P2093
P356
P1476
Single-nucleotide polymorphism ...... sporter ABCG2 (MXR/BCRP/ABCP1)
@en
P2093
Jeffrey Hung
Kuniaki Morisaki
Lyn Mickley Huff
Michael Dean
Susan E Bates
Yasumasa Honjo
P304
P356
10.4161/CBT.322
P50
P577
2002-11-01T00:00:00Z