Stereospecific Metabolism of R- and S-Warfarin by Human Hepatic Cytosolic Reductases.

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Stereospecific Metabolism of R- and S-Warfarin by Human Hepatic Cytosolic Reductases.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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2017年學術文章

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name

Stereospecific Metabolism of R- and S-Warfarin by Human Hepatic Cytosolic Reductases.

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Stereospecific Metabolism of R- and S-Warfarin by Human Hepatic Cytosolic Reductases.

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Item

label

Stereospecific Metabolism of R- and S-Warfarin by Human Hepatic Cytosolic Reductases.

@en

Stereospecific Metabolism of R- and S-Warfarin by Human Hepatic Cytosolic Reductases.

@nl

prefLabel

Stereospecific Metabolism of R- and S-Warfarin by Human Hepatic Cytosolic Reductases.

@en

Stereospecific Metabolism of R- and S-Warfarin by Human Hepatic Cytosolic Reductases.

@nl

P1476

Stereospecific Metabolism of R- and S-Warfarin by Human Hepatic Cytosolic Reductases

@en

P2093

Bryce P Johnson

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Dustyn A Barnette

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Linda P Desrochers

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Robert Nshimiyimana

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Thomas E Goodwin

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P2860

Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family members

Multiple UDP-glucuronosyltransferases in human liver microsomes glucuronidate both R- and S-7-hydroxywarfarin into two metabolites.

Inhibitor selectivity between aldo-keto reductase superfamily members AKR1B10 and AKR1B1: role of Trp112 (Trp111)

Clinical Practice Recommendations on Genetic Testing of CYP2C9 and VKORC1 Variants in Warfarin Therapy

A cellular system for quantitation of vitamin K cycle activity: structure-activity effects on vitamin K antagonism by warfarin metabolites.

Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).

Role of aldo-keto reductase family 1 (AKR1) enzymes in human steroid metabolism

Substrate-directed stereoselectivity in vicinal diamine-catalyzed synthesis of warfarin.

Bleeding complications with warfarin use: a prevalent adverse effect resulting in regulatory action.

Type 5 17beta-hydroxysteroid dehydrogenase/prostaglandin F synthase (AKR1C3): role in breast cancer and inhibition by non-steroidal anti-inflammatory drug analogs.

P304

1000-1007

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scholarly article

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10.1124/DMD.117.075929

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P433

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P478

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Grover P Miller

Dakota L Pouncey

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2017-06-23T00:00:00Z

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28646078

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5539582

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