Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms.
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Role of tyrosine-kinase inhibitors in myeloproliferative neoplasms: comparative lessons learnedRecent advances in understanding myelofibrosis and essential thrombocythemiaOvercoming treatment challenges in myelofibrosis and polycythemia vera: the role of ruxolitinibEvolving Therapeutic Strategies for the Classic Philadelphia-Negative Myeloproliferative NeoplasmsInflammation as a Keystone of Bone Marrow Stroma Alterations in Primary MyelofibrosisMPNs as Inflammatory Diseases: The Evidence, Consequences, and PerspectivesThe Role of Reactive Oxygen Species in Myelofibrosis and Related NeoplasmsPathogenesis of Myeloproliferative Neoplasms: Role and Mechanisms of Chronic InflammationAcute Myeloid Leukemia and Other Types of Disease Progression in Myeloproliferative NeoplasmsPolycythemia vera and essential thrombocythemia: 2015 update on diagnosis, risk-stratification and managementLong-term survival and blast transformation in molecularly annotated essential thrombocythemia, polycythemia vera, and myelofibrosisCorrelation of mutation profile and response in patients with myelofibrosis treated with ruxolitinib.Managing Patients With Myelofibrosis in the Era of Janus Kinase InhibitorsMonitoring Minimal Residual Disease in the Myeloproliferative Neoplasms: Current Applications and Emerging ApproachesCalreticulin (CALR) mutation in myeloproliferative neoplasms (MPNs)Estimation of diagnosis and prognosis in ET by assessment of CALR and JAK2V617F mutations and laboratory findings: a meta-analysis.SubcloneSeeker: a computational framework for reconstructing tumor clone structure for cancer variant interpretation and prioritization.Clinicopathological differences exist between CALR- and JAK2-mutated myeloproliferative neoplasms despite a similar molecular landscape: data from targeted next-generation sequencing in the diagnostic laboratory.Clinical effect of driver mutations of JAK2, CALR, or MPL in primary myelofibrosisRuxolitinib: long-term management of patients with myelofibrosis and future directions in the treatment of myeloproliferative neoplasms2016 WHO Clinical Molecular and Pathological Criteria for Classification and Staging of Myeloproliferative Neoplasms (MPN) Caused by MPN Driver Mutations in the JAK2, MPL and CALR Genes in the Context of New 2016 WHO Classification: Prognostic and TComparison of the Mutational Profiles of Primary Myelofibrosis, Polycythemia Vera, and Essential ThrombocytosisIncreased B cell activation is present in JAK2V617F-mutated, CALR-mutated and triple-negative essential thrombocythemia.Myeloproliferative neoplasms can be initiated from a single hematopoietic stem cell expressing JAK2-V617F.The mutation profile of JAK2 and CALR in Chinese Han patients with Philadelphia chromosome-negative myeloproliferative neoplasms.Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis.Calreticulin exon 9 mutations in myeloproliferative neoplasms.Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice promote disease progression in myeloproliferative neoplasms.The molecular basis of myeloid malignancies.Clonal evolution revealed by whole genome sequencing in a case of primary myelofibrosis transformed to secondary acute myeloid leukemiaDissecting Genomic Aberrations in Myeloproliferative Neoplasms by Multiplex-PCR and Next Generation Sequencing.CD133 marks a stem cell population that drives human primary myelofibrosis.Analysis of phenotype and outcome in essential thrombocythemia with CALR or JAK2 mutations.Differential Dynamics of CALR Mutant Allele Burden in Myeloproliferative Neoplasms during Interferon Alfa Treatment.Visualizing tumor evolution with the fishplot package for RMyeloproliferative Neoplasms in ChildrenEffect of mutation order on myeloproliferative neoplasms.Differential clinical effects of different mutation subtypes in CALR-mutant myeloproliferative neoplasms.Genomic dynamics associated with malignant transformation in IDH1 mutated gliomas.Efficacy and safety of ruxolitinib in the treatment of patients with myelofibrosis.
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P2860
Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Clonal evolution and clinical ...... myeloproliferative neoplasms.
@en
Clonal evolution and clinical ...... myeloproliferative neoplasms.
@nl
type
label
Clonal evolution and clinical ...... myeloproliferative neoplasms.
@en
Clonal evolution and clinical ...... myeloproliferative neoplasms.
@nl
prefLabel
Clonal evolution and clinical ...... myeloproliferative neoplasms.
@en
Clonal evolution and clinical ...... myeloproliferative neoplasms.
@nl
P2093
P50
P1433
P1476
Clonal evolution and clinical ...... myeloproliferative neoplasms.
@en
P2093
Axel Karow
Christian Beisel
Hui Hao-Shen
Ina Nissen
Martin Stern
Pontus Lundberg
Radek C Skoda
Renate Looser
Sabine Girsberger
Thomas Lehmann
P304
P356
10.1182/BLOOD-2013-11-537167
P407
P577
2014-01-29T00:00:00Z