LASSBio-1829 Hydrochloride: Development of a New Orally Active N-Acylhydrazone IKK2 Inhibitor with Anti-inflammatory Properties.

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Discovery of Novel Orally Active Tetrahydro-Naphthyl-N-Acylhydrazones with In Vivo Anti-TNF-α Effect and Remarkable Anti-Inflammatory Properties Discovery of naphthyl-N-acylhydrazone p38α MAPK inhibitors with in vivo anti-inflammatory and anti-TNF-α activity.

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LASSBio-1829 Hydrochloride: Development of a New Orally Active N-Acylhydrazone IKK2 Inhibitor with Anti-inflammatory Properties.

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http://www.wikidata.org/entity/Q54250623

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2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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LASSBio-1829 Hydrochloride: De ...... Anti-inflammatory Properties.

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LASSBio-1829 Hydrochloride: De ...... Anti-inflammatory Properties.

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LASSBio-1829 Hydrochloride: De ...... Anti-inflammatory Properties.

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LASSBio-1829 Hydrochloride: De ...... Anti-inflammatory Properties.

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LASSBio-1829 Hydrochloride: De ...... Anti-inflammatory Properties.

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LASSBio-1829 Hydrochloride: De ...... Anti-inflammatory Properties.

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LASSBio-1829 Hydrochloride: De ...... h Anti-inflammatory Properties

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Laurent E Dardenne

http://www.w3.org/2001/XMLSchema#string

Natália M Cordeiro

http://www.w3.org/2001/XMLSchema#string

Patrícia D Fernandes

http://www.w3.org/2001/XMLSchema#string

Rosana H C N Freitas

http://www.w3.org/2001/XMLSchema#string

Tayna S Valerio

http://www.w3.org/2001/XMLSchema#string

Thaís S do Nascimento

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IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

MolProbity: all-atom structure validation for macromolecular crystallography

BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinities

Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer

Basic local alignment search tool

Structural insight into nucleotide recognition by human death-associated protein kinase

Crystal structure of inhibitor of κB kinase β

Crystal Structure of a Human I B Kinase Asymmetric Dimer

High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design

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234-244

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scholarly article

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10.1002/CMDC.201500266

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http://www.w3.org/2001/XMLSchema#string

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http://www.w3.org/2001/XMLSchema#string

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Carlos Fraga

Isabella A Guedes

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2015-08-25T00:00:00Z

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P698

26306006

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LASSBio-1829 Hydrochloride: Development of a New Orally Active N-Acylhydrazone IKK2 Inhibitor with Anti-inflammatory Properties.

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P2860

P2860

LASSBio-1829 Hydrochloride: Development of a New Orally Active N-Acylhydrazone IKK2 Inhibitor with Anti-inflammatory Properties.

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