Combined regulation of mTORC1 and lysosomal acidification by GSK-3 suppresses autophagy and contributes to cancer cell growth.
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Knockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cellsAutophagy is a signature of a signaling network that maintains hematopoietic stem cellsBufalin enhances antitumor effect of paclitaxel on cervical tumorigenesis via inhibiting the integrin α2/β5/FAK signaling pathwayAutophagy activity is associated with membranous sodium iodide symporter expression and clinical response to radioiodine therapy in non-medullary thyroid cancerGsk3 is a metabolic checkpoint regulator in B cells.Inhibition of glycogen synthase kinase 3 beta (GSK3β) suppresses the progression of esophageal squamous cell carcinoma by modifying STAT3 activity.Downregulation of KDM4A Suppresses the Survival of Glioma Cells by Promoting Autophagy.GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signallingTauopathy induced by low level expression of a human brain-derived tau fragment in mice is rescued by phenylbutyrate.Whey Protein Concentrate Renders MDA-MB-231 Cells Sensitive to Rapamycin by Altering Cellular Redox State and Activating GSK3β/mTOR Signaling.Multifaceted Roles of GSK-3 in Cancer and Autophagy-Related Diseases.GSK3β Controls mTOR and Prosurvival Signaling in Neurons.A unique type of GSK-3 inhibitor brings new opportunities to the clinic.GSK-3β inhibits autophagy and enhances radiosensitivity in non-small cell lung cancer.SB-216763, a GSK-3β inhibitor, protects against aldosterone-induced cardiac, and renal injury by activating autophagy.
P2860
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P2860
Combined regulation of mTORC1 and lysosomal acidification by GSK-3 suppresses autophagy and contributes to cancer cell growth.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
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2014年學術文章
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name
Combined regulation of mTORC1 ...... ributes to cancer cell growth.
@en
Combined regulation of mTORC1 ...... ributes to cancer cell growth.
@nl
type
label
Combined regulation of mTORC1 ...... ributes to cancer cell growth.
@en
Combined regulation of mTORC1 ...... ributes to cancer cell growth.
@nl
prefLabel
Combined regulation of mTORC1 ...... ributes to cancer cell growth.
@en
Combined regulation of mTORC1 ...... ributes to cancer cell growth.
@nl
P2093
P2860
P356
P1433
P1476
Combined regulation of mTORC1 ...... ributes to cancer cell growth.
@en
P2093
I Azoulay-Alfaguter
L Avrahami
P2860
P2888
P304
P356
10.1038/ONC.2014.390
P407
P577
2014-12-15T00:00:00Z
P5875
P6179
1022194028