about
Discovery of Gemilukast (ONO-6950), a Dual CysLT1 and CysLT2 Antagonist As a Therapeutic Agent for Asthma.Roles of basophils and mast cells infiltrating the lung by multiple antigen challenges in asthmatic responses of miceInterleukin (IL)-33: new therapeutic target for atopic diseases.Involvement of galectin-9 in guinea pig allergic airway inflammation.Important role of neutrophils in the late asthmatic response in mice.Intratracheal sensitization/challenge-induced biphasic asthmatic response and airway hyperresponsiveness in guinea pigs.Development of cigarette smoke solution- and lipopolysaccharide-induced pulmonary emphysema in guinea pigs.Complement C3a regulates late asthmatic response and airway hyperresponsiveness in mice.Effect of a peroxynitrite scavenger, a manganese-porphyrin compound on airway remodeling in a murine asthma.l-Ephedrine is a major constituent of Mao-Bushi-Saishin-To, one of the formulas of Chinese medicine, which shows immediate inhibition after oral administration of passive cutaneous anaphylaxis in rats.Markedly increased nasal blockage by intranasal leukotriene D4 in an experimental allergic rhinitis model: contribution of dilated mucosal blood vessels.No involvement of interleukin-5 or eosinophils in experimental allergic rhinitis in guinea pigs.Cysteinyl leukotriene-dependent interleukin-5 production leading to eosinophilia during late asthmatic response in guinea-pigs.Augmentation of spontaneous cough by enalapril through up-regulation of bradykinin B1 receptors in guinea pigs.Effects of TAK-427 on acute nasal symptoms and nasal obstruction in guinea pig model of experimental allergic rhinitis.Acquired nasal hyperresponsiveness aggravates antigen-induced rhinitis in the guinea pig.Intratracheal dosing with disodium cromoglycate inhibits late asthmatic response by attenuating eicosanoid production in guinea pigs.Synergism between cysteinyl leukotrienes and thromboxane A2 to induce allergic late phase nasal blockage in guinea pigs.Preparation of 2- and 4-(2-alkylcarbamoyl-1-methylvinyl)-7-alkyloxybenzo[b]furans having potent antagonistic activity against human leukotriene B4 BLT1 and/or BLT2 receptors.Effect of TA-270, a novel quinolinone derivative, on antigen-induced nasal blockage in a guinea pig model of allergic rhinitis.Mast cell hyperplasia induced by multiple challenge with cedar pollen in sensitised guinea pigs.Effect of local nasal immunotherapy on nasal blockage in pollen-induced allergic rhinitis of Guinea pigs.Carrageenans can regulate the pulmonary absorption of antiasthmatic drugs and their retention in the rat lung tissues without any membrane damage.Delayed-type asthmatic response induced by repeated intratracheal exposure to toluene-2,4-diisocyanate in guinea pigs.Synthesis of 2-, 4- and 5-(2-alkylcarbamoyl-1-methylvinyl)-7-alkyloxybenzo[b]furans and their leukotriene B4 receptor antagonistic activity.Effects of KP-496, a novel dual antagonist of leukotriene D(4) and thromboxane A (2) receptors on nasal blockage in guinea pig models of allergic rhinitis.Detection of new antigenic proteins in Japanese cedar pollen.Effects of multiple dexamethasone treatments on aggravation of allergic conjunctivitis associated with mast cell hyperplasia.Absence of nasal blockage in a Japanese cedar pollen-induced allergic rhinitis model mouse.[Pharmacological analyses of mechanisms underlying nasal blockage using a guinea-pig model of allergic rhinitis].Inhibition of hematopoietic prostaglandin D synthase improves allergic nasal blockage in guinea pigs.Polycyclic aromatic hydrocarbons aggravate antigen-induced nasal blockage in experimental allergic rhinitis.A new CysLT1 and CysLT2 receptors-mediated anaphylaxis guinea pig model.Analysis of major paralogs encoding the Fra a 1 allergen based on their organ-specificity in Fragaria × ananassa.CysLT2 receptor activation is involved in LTC4-induced lung air-trapping in guinea pigs.Eicosapentaenoic acid ethyl ester ameliorates atopic dermatitis-like symptoms in special diet-fed hairless mice, partly by restoring covalently bound ceramides in the stratum corneum.Dietary deficiencies of unsaturated fatty acids and starch cause atopic dermatitis-like pruritus in hairless mice.Topical ocular treatment with monoclonal antibody Fab fragments targeting Japanese cedar pollen Cry j 1 inhibits Japanese cedar pollen-induced allergic conjunctivitis in mice.Expression of CysLT2 receptors in asthma lung, and their possible role in bronchoconstriction.Antigen-specific airway IL-33 production depends on FcγR-mediated incorporation of the antigen by alveolar macrophages in sensitized mice.
P50
Q34486368-0F0AE424-139A-448E-BAC4-3C01CADF1944Q36836453-207B227B-B83E-4E4C-8B85-CB04F594D92BQ38248529-508F945E-BE22-448D-9CF9-07DA73B56181Q42622467-560817D7-41F2-46F8-857F-24DE0146D622Q42780443-AC40085E-FD58-402D-B35D-EACF4F925A02Q42783704-E5466AFF-9C7A-447C-B7EF-B0659E892E11Q43194068-0E9F32E7-F594-4772-9490-DE8CB7DE0537Q43291196-2397B098-659E-4D13-AF42-DF82D0E7F5C1Q43469603-EB78BE19-CC0E-4D01-B04C-7B40E5246D06Q43508183-9EF164FA-6A13-460D-8C6C-12F071AFEA38Q43679364-CE68C1D2-25B7-49BF-B82F-7855D7FC8315Q43950305-6BB0E58B-3215-4AF2-9DDF-FFEBD3A54758Q43969567-9C40C08A-543D-428B-8A22-05C248A8DC6FQ44551697-8C4CBCBC-9BBA-46AD-B727-F17BB0540BE8Q44582089-B1B9F3F6-B6CB-4AEC-AD50-469D01866156Q44737403-F2B51AAC-A259-4EDF-A986-19F07CCABA88Q45024846-0DAC3387-F319-447B-BDA2-CC88F8AEED9EQ45160204-C29DC4C1-3ED2-4AA5-8FE1-9D750EBF2215Q45163636-D62D5D72-E4E2-45D2-9DEE-A79344706521Q46235989-666987A3-90B6-4D5B-9F12-EE90CCEB3F99Q46265982-F950B1E6-EF7B-412A-B68F-778322C69C45Q46337412-994FF2F7-0429-48B1-BC11-90AF51C1A37CQ46390724-C3BDCA27-4F91-443E-B06E-82EEE4A530EDQ46459112-CF8C167C-019A-49FA-9525-00F0F42E345AQ46511221-902A00BE-2CE2-4721-A80D-2E4E704087F1Q46564120-260F264B-9B74-4930-984B-DD62FFA10D38Q46712747-68A0686B-1F80-4055-BF03-D159CC2491F7Q46725436-8B13ACD5-B7C2-4452-A88B-1A297E12D1B7Q46746065-FC7D3150-50DE-493C-BFA3-328437E70B43Q46798835-717492D7-9ED2-4456-8ABA-AB1F4223A043Q46891444-A85412AB-4E41-420F-A69F-7F51DD9D230FQ46911776-7D9B1372-BA14-48C9-ACD2-21B8AF47B08EQ46962534-B33D2535-D545-4DE2-AD88-0B5A34B7D698Q47312084-59FDA81F-3852-469E-B2FB-08049C23F163Q48033443-5CD67BB7-3EFB-4B27-AB2F-247258FA0B83Q50214219-31C019B7-FF94-4D41-AB45-BE4408BF346EQ50614933-84E0CBD0-511C-4AD3-9868-F5785024F3C0Q51170893-8F3C451E-07E2-4F3A-BC43-4AFF17F86A4CQ51587742-BA2B42D3-CB68-4F4F-AB7C-EF207335DB42Q52345049-F02CD194-9D1D-4995-BAB1-7EB85075C276
P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Takeshi Nabe
@ast
Takeshi Nabe
@en
Takeshi Nabe
@es
Takeshi Nabe
@nl
Takeshi Nabe
@sl
type
label
Takeshi Nabe
@ast
Takeshi Nabe
@en
Takeshi Nabe
@es
Takeshi Nabe
@nl
Takeshi Nabe
@sl
prefLabel
Takeshi Nabe
@ast
Takeshi Nabe
@en
Takeshi Nabe
@es
Takeshi Nabe
@nl
Takeshi Nabe
@sl
P106
P1153
7004208603
P31
P496
0000-0002-5225-8375