Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis.
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Role of Hedgehog Signaling Pathway in NASHEndothelial to Mesenchymal Transition (EndoMT) in the Pathogenesis of Human Fibrotic DiseasesScleroderma pathogenesis: a pivotal role for fibroblasts as effector cellsMyofibroblastsAlcohol activates the hedgehog pathway and induces related procarcinogenic processes in the alcohol-preferring rat model of hepatocarcinogenesis.Sonic hedgehog signaling in the lung. From development to disease.Crosstalk between Shh and TGF-β signaling in cyclosporine-enhanced cell proliferation in human gingival fibroblasts.Rhein, a natural anthraquinone derivative, attenuates the activation of pancreatic stellate cells and ameliorates pancreatic fibrosis in mice with experimental chronic pancreatitis.Interleukin-1β attenuates myofibroblast formation and extracellular matrix production in dermal and lung fibroblasts exposed to transforming growth factor-β1Lung fibroblasts share mesenchymal stem cell features which are altered in chronic obstructive pulmonary disease via the overactivation of the Hedgehog signaling pathwayReemergence of hedgehog mediates epithelial-mesenchymal crosstalk in pulmonary fibrosis.Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages.The Effect of rhCygb on CCl4-Induced Hepatic Fibrogenesis in Rat.Sonic hedgehog delivery from self-assembled nanofiber hydrogels reduces the fibrotic response in models of erectile dysfunction.Hedgehog signaling in neonatal and adult lung.Morphogen pathways in systemic sclerosis.Canonical Wnt signalling as a key regulator of fibrogenesis - implications for targeted therapies?Novel investigational agents for the treatment of scleroderma.Mechanisms of initiation and progression of intestinal fibrosis in IBD.Endothelial to mesenchymal transition (EndoMT) in the pathogenesis of Systemic Sclerosis-associated pulmonary fibrosis and pulmonary arterial hypertension. Myth or reality?Sonic hedgehog signaling in kidney fibrosis: a master communicator.MicroRNA-370 Attenuates Hepatic Fibrogenesis by Targeting Smoothened.Role of Shh and TGF in cyclosporine-enhanced expression of collagen and α-SMA by gingival fibroblast.Cyclosporine A up-regulates Sonic hedgehog in gingiva: role of the up-regulation on gingival cell proliferation.New treatment directions for IPF: current status of ongoing and upcoming clinical trials.Influenza NS1 directly modulates Hedgehog signaling during infection.Small molecule-mediated inhibition of myofibroblast transdifferentiation for the treatment of fibrosis.TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases.Diabetes Aggravates Post-ischaemic Renal Fibrosis through Persistent Activation of TGF-β1 and Shh Signalling.Anti-fibrotic effects of pirfenidone by interference with the hedgehog signalling pathway in patients with systemic sclerosis-associated interstitial lung disease.Noncanonical hedgehog pathway activation through SRF-MKL1 promotes drug resistance in basal cell carcinomas.Targeting the hedgehog-glioma-associated oncogene homolog pathway inhibits bleomycin-induced lung fibrosis in mice.Role of Sonic Hedgehog in idiopathic pulmonary fibrosis.Differential Expression of Hedgehog and Snail in Cutaneous Fibrosing Disorders: Implications for Targeted Inhibition.Human Fibrotic Diseases: Current Challenges in Fibrosis Research.Tribbles homologue 3 stimulates canonical TGF-β signalling to regulate fibroblast activation and tissue fibrosis.Combined inhibition of morphogen pathways demonstrates additive antifibrotic effects and improved tolerability.[Structure of the Smoothened receptor].
P2860
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P2860
Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh-hant
name
Hedgehog signaling controls fi ...... ibrosis in systemic sclerosis.
@en
Hedgehog signaling controls fi ...... ibrosis in systemic sclerosis.
@nl
type
label
Hedgehog signaling controls fi ...... ibrosis in systemic sclerosis.
@en
Hedgehog signaling controls fi ...... ibrosis in systemic sclerosis.
@nl
prefLabel
Hedgehog signaling controls fi ...... ibrosis in systemic sclerosis.
@en
Hedgehog signaling controls fi ...... ibrosis in systemic sclerosis.
@nl
P2093
P2860
P356
P1476
Hedgehog signaling controls fi ...... ibrosis in systemic sclerosis.
@en
P2093
Alfiya Akhmetshina
Angelika Horn
Cinzia Cordazzo
Clara Dees
Elisabeth Traiffort
Hermine Roudaut
Jochen Zwerina
Johannes Gusinde
Jörg H W Distler
Katrin Palumbo
P2860
P304
P356
10.1002/ART.34444
P577
2012-08-01T00:00:00Z