Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis. - Wikidata - awgldk - TriplyDB

Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis.

Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis.

http://www.wikidata.org/entity/Q54322921

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Role of Hedgehog Signaling Pathway in NASH Endothelial to Mesenchymal Transition (EndoMT) in the Pathogenesis of Human Fibrotic Diseases Scleroderma pathogenesis: a pivotal role for fibroblasts as effector cells Myofibroblasts Alcohol activates the hedgehog pathway and induces related procarcinogenic processes in the alcohol-preferring rat model of hepatocarcinogenesis.Sonic hedgehog signaling in the lung. From development to disease.Crosstalk between Shh and TGF-β signaling in cyclosporine-enhanced cell proliferation in human gingival fibroblasts.Rhein, a natural anthraquinone derivative, attenuates the activation of pancreatic stellate cells and ameliorates pancreatic fibrosis in mice with experimental chronic pancreatitis.Interleukin-1β attenuates myofibroblast formation and extracellular matrix production in dermal and lung fibroblasts exposed to transforming growth factor-β1 Lung fibroblasts share mesenchymal stem cell features which are altered in chronic obstructive pulmonary disease via the overactivation of the Hedgehog signaling pathway Reemergence of hedgehog mediates epithelial-mesenchymal crosstalk in pulmonary fibrosis.Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages.The Effect of rhCygb on CCl4-Induced Hepatic Fibrogenesis in Rat.Sonic hedgehog delivery from self-assembled nanofiber hydrogels reduces the fibrotic response in models of erectile dysfunction.Hedgehog signaling in neonatal and adult lung.Morphogen pathways in systemic sclerosis.Canonical Wnt signalling as a key regulator of fibrogenesis - implications for targeted therapies?Novel investigational agents for the treatment of scleroderma.Mechanisms of initiation and progression of intestinal fibrosis in IBD.Endothelial to mesenchymal transition (EndoMT) in the pathogenesis of Systemic Sclerosis-associated pulmonary fibrosis and pulmonary arterial hypertension. Myth or reality?Sonic hedgehog signaling in kidney fibrosis: a master communicator.MicroRNA-370 Attenuates Hepatic Fibrogenesis by Targeting Smoothened.Role of Shh and TGF in cyclosporine-enhanced expression of collagen and α-SMA by gingival fibroblast.Cyclosporine A up-regulates Sonic hedgehog in gingiva: role of the up-regulation on gingival cell proliferation.New treatment directions for IPF: current status of ongoing and upcoming clinical trials.Influenza NS1 directly modulates Hedgehog signaling during infection.Small molecule-mediated inhibition of myofibroblast transdifferentiation for the treatment of fibrosis.TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases.Diabetes Aggravates Post-ischaemic Renal Fibrosis through Persistent Activation of TGF-β1 and Shh Signalling.Anti-fibrotic effects of pirfenidone by interference with the hedgehog signalling pathway in patients with systemic sclerosis-associated interstitial lung disease.Noncanonical hedgehog pathway activation through SRF-MKL1 promotes drug resistance in basal cell carcinomas.Targeting the hedgehog-glioma-associated oncogene homolog pathway inhibits bleomycin-induced lung fibrosis in mice.Role of Sonic Hedgehog in idiopathic pulmonary fibrosis.Differential Expression of Hedgehog and Snail in Cutaneous Fibrosing Disorders: Implications for Targeted Inhibition.Human Fibrotic Diseases: Current Challenges in Fibrosis Research.Tribbles homologue 3 stimulates canonical TGF-β signalling to regulate fibroblast activation and tissue fibrosis.Combined inhibition of morphogen pathways demonstrates additive antifibrotic effects and improved tolerability.[Structure of the Smoothened receptor].

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P2860

Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis.

http://www.wikidata.org/entity/Q54322921

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2012 nî lūn-bûn

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Hedgehog signaling controls fi ...... ibrosis in systemic sclerosis.

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Hedgehog signaling controls fi ...... ibrosis in systemic sclerosis.

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Hedgehog signaling controls fi ...... ibrosis in systemic sclerosis.

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Hedgehog signaling controls fi ...... ibrosis in systemic sclerosis.

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Hedgehog signaling controls fi ...... ibrosis in systemic sclerosis.

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Hedgehog signaling controls fi ...... ibrosis in systemic sclerosis.

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Arthritis and Rheumatism

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Hedgehog signaling controls fi ...... ibrosis in systemic sclerosis.

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Alfiya Akhmetshina

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Angelika Horn

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Cinzia Cordazzo

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Clara Dees

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Elisabeth Traiffort

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Hermine Roudaut

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Jochen Zwerina

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Johannes Gusinde

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Jörg H W Distler

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Katrin Palumbo

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P2860

Activating Smoothened mutations in sporadic basal-cell carcinoma

TGF-β/SMAD/GLI2 signaling axis in cancer progression and metastasis

Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours

Mutations affecting segment number and polarity in Drosophila

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord

Altered neural cell fates and medulloblastoma in mouse patched mutants

Sonic hedgehog regulates branching morphogenesis in the mammalian lung

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

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10.1002/ART.34444

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8

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64

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Jérôme Avouac

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221851591

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