Tongxinluo inhibits vascular inflammation and neointimal hyperplasia through blockade of the positive feedback loop between miR-155 and TNF-α.
about
Chinese medicine Tongxinluo reduces atherosclerotic lesion by attenuating oxidative stress and inflammation in microvascular endothelial cells.miR-155 acts as an anti-inflammatory factor in atherosclerosis-associated foam cell formation by repressing calcium-regulated heat stable protein 1.Tongxinluo inhibits cyclooxygenase-2, inducible nitric oxide synthase, hypoxia-inducible factor-2α/vascular endothelial growth factor to antagonize injury in hypoxia-stimulated cardiac microvascular endothelial cells.Tongxinluo inhibits neointimal formation by regulating the expression and post-translational modification of KLF5 in macrophages.Expecting the holistic regulation from Chinese medicine based on the "solar system" hypothesis of ischemic heart disease.Inhibition of miR-128-3p by Tongxinluo Protects Human Cardiomyocytes from Ischemia/reperfusion Injury via Upregulation of p70s6k1/p-p70s6k1.Tongxinluo Inhibits Renal Fibrosis in Diabetic Nephropathy: Involvement of the Suppression of Intercellular Transfer of TGF-[Formula: see text]1-Containing Exosomes from GECs to GMCs.Exosome-Mediated miR-155 Transfer from Smooth Muscle Cells to Endothelial Cells Induces Endothelial Injury and Promotes Atherosclerosis.miR-29a regulates vascular neointimal hyperplasia by targeting YY1.Macrophages Aggravate Hypoxia-Induced Cardiac Microvascular Endothelial Cell Injury via Peroxynitrite: Protection by Tongxinluo.Role of miR-124 and miR-141 in the regulation of vascular reactivity and the relationship to RhoA and Rac1 after hemorrhage and hypoxia.Chinese medicine Tongxinluo increases tight junction protein levels by inducing KLF5 expression in microvascular endothelial cells.Potential Effectiveness of Chinese Patent Medicine for Secondary Prevention After Acute Myocardial Infarction: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
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P2860
Tongxinluo inhibits vascular inflammation and neointimal hyperplasia through blockade of the positive feedback loop between miR-155 and TNF-α.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Tongxinluo inhibits vascular i ...... oop between miR-155 and TNF-α.
@en
Tongxinluo inhibits vascular i ...... oop between miR-155 and TNF-α.
@nl
type
label
Tongxinluo inhibits vascular i ...... oop between miR-155 and TNF-α.
@en
Tongxinluo inhibits vascular i ...... oop between miR-155 and TNF-α.
@nl
prefLabel
Tongxinluo inhibits vascular i ...... oop between miR-155 and TNF-α.
@en
Tongxinluo inhibits vascular i ...... oop between miR-155 and TNF-α.
@nl
P2093
P2860
P1476
Tongxinluo inhibits vascular i ...... oop between miR-155 and TNF-α.
@en
P2093
Jin-kun Wen
Jing Zhang
Ruo-nan Zhang
Xin-hua Zhang
P2860
P304
P356
10.1152/AJPHEART.00936.2013
P577
2014-08-01T00:00:00Z