about
Targeting of somatic hypermutation by immunoglobulin enhancer and enhancer-like sequences.Bcl6 Is Required for Somatic Hypermutation and Gene Conversion in Chicken DT40 Cells.Gene interaction network regulates plasma cell differentiation.Bach2 regulates AID-mediated immunoglobulin gene conversion and somatic hypermutation in DT40 B cells.IRF4 Deficiency Leads to Altered BCR Signalling Revealed by Enhanced PI3K Pathway, Decreased SHIP Expression and Defected Cytoskeletal Responses.Concerted action of Helios and Ikaros controls the expression of the inositol 5-phosphatase SHIP.Ikaros has a crucial role in regulation of B cell receptor signaling.BLIMP-1 is insufficient to induce antibody secretion in the absence of IRF4 in DT40 cells.Super-enhancer transcription converges on AID.Transcription factor binding at Ig enhancers is linked to somatic hypermutation targetingTopologically Associated Domains Delineate Susceptibility to Somatic Hypermutation
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description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Jukka Alinikula
@ast
Jukka Alinikula
@en
Jukka Alinikula
@es
Jukka Alinikula
@nl
Jukka Alinikula
@sl
type
label
Jukka Alinikula
@ast
Jukka Alinikula
@en
Jukka Alinikula
@es
Jukka Alinikula
@nl
Jukka Alinikula
@sl
prefLabel
Jukka Alinikula
@ast
Jukka Alinikula
@en
Jukka Alinikula
@es
Jukka Alinikula
@nl
Jukka Alinikula
@sl
P106
P21
P31
P496
0000-0001-9926-6439