Feedbacks and adaptive capabilities of the PI3K/Akt/mTOR axis in acute myeloid leukemia revealed by pathway selective inhibition and phosphoproteome analysis.
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Phosphoproteome Analysis Reveals Differential Mode of Action of Sorafenib in Wildtype and Mutated FLT3 Acute Myeloid Leukemia (AML) CellsWhole proteome analysis of mouse lymph nodes in cutaneous anthraxA pilot study exploring the molecular architecture of the tumor microenvironment in human prostate cancer using laser capture microdissection and reverse phase protein microarray.Targeting mTOR signaling pathways and related negative feedback loops for the treatment of acute myeloid leukemia.Inhibition of mTOR by apigenin in UVB-irradiated keratinocytes: A new implication of skin cancer preventionPhase II study of an AKT inhibitor MK2206 in patients with relapsed or refractory lymphoma.Role of phosphoproteomics in the development of personalized cancer therapies.Targeting PI3K/AKT/mTOR network for treatment of leukemia.Outlook on PI3K/AKT/mTOR inhibition in acute leukemia.Targeting mTOR for the treatment of B cell malignancies.Targeting autophagy as a strategy for drug discovery and therapeutic modulation.Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent Akt reactivation.Impact of phosphoproteomics in the translation of kinase-targeted therapies.Activating c-KIT mutations confer oncogenic cooperativity and rescue RUNX1/ETO-induced DNA damage and apoptosis in human primary CD34+ hematopoietic progenitors.Reversal of the glycolytic phenotype of primary effusion lymphoma cells by combined targeting of cellular metabolism and PI3K/Akt/ mTOR signaling.Phosphorylation, Signaling, and Cancer: Targets and Targeting.Inhibition of PI3K Signalling Selectively Affects Medulloblastoma Cancer Stem Cells.Comprehensive Analysis of Cancer-Proteogenome to Identify Biomarkers for the Early Diagnosis and Prognosis of Cancer.Expression and functional proteomic analyses of osteocytes from Xenopus laevis tested under mechanical stress conditions: preliminary observations on an appropriate new animal model.Dual targeting of eIF4E by blocking MNK and mTOR pathways in leukemia.Phosphoproteomics-Based Profiling of Kinase Activities in Cancer Cells.Inhibition of Ras-mediated signaling pathways in CML stem cells.
P2860
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P2860
Feedbacks and adaptive capabilities of the PI3K/Akt/mTOR axis in acute myeloid leukemia revealed by pathway selective inhibition and phosphoproteome analysis.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
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2014年學術文章
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name
Feedbacks and adaptive capabil ...... and phosphoproteome analysis.
@en
Feedbacks and adaptive capabil ...... and phosphoproteome analysis.
@nl
type
label
Feedbacks and adaptive capabil ...... and phosphoproteome analysis.
@en
Feedbacks and adaptive capabil ...... and phosphoproteome analysis.
@nl
prefLabel
Feedbacks and adaptive capabil ...... and phosphoproteome analysis.
@en
Feedbacks and adaptive capabil ...... and phosphoproteome analysis.
@nl
P2093
P2860
P50
P356
P1433
P1476
Feedbacks and adaptive capabil ...... n and phosphoproteome analysis
@en
P2093
A M Martelli
E Petricoin
F Forghieri
P2860
P2888
P304
P356
10.1038/LEU.2014.123
P50
P577
2014-04-04T00:00:00Z