IL-15 constrains mast cell-dependent antibacterial defenses by suppressing chymase activities.
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The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic useNew developments in mast cell biologySyntaxin 11 is required for NK and CD8⁺ T-cell cytotoxicity and neutrophil degranulationMast cell-derived TNF can exacerbate mortality during severe bacterial infections in C57BL/6-KitW-sh/W-sh mice.Biological implications of preformed mast cell mediators.Immunomodulatory mast cells: negative, as well as positive, regulators of immunityIL-15 prevents apoptosis, reverses innate and adaptive immune dysfunction, and improves survival in sepsis.Serglycin-independent release of active mast cell proteases in response to Toxoplasma gondii infection.Mast cell function: a new vision of an old cell.IL-15 Enables Septic Shock by Maintaining NK Cell Integrity and Function.Fish oil attenuates omega-6 polyunsaturated fatty acid-induced dysbiosis and infectious colitis but impairs LPS dephosphorylation activity causing sepsis.Insights into potential pathogenesis mechanisms associated with Campylobacter jejuni-induced abortion in ewes.Generation of a new congenic mouse strain with enhanced chymase expression in mast cells.Mast cell secretory granules: armed for battle.Differential regulation of mast cell degranulation versus cytokine secretion by the actin regulatory proteins Coronin1a and Coronin1b.Sphingosine-1-phosphate induces development of functionally mature chymase-expressing human mast cells from hematopoietic progenitors.Mast cell-orchestrated immunity to pathogens.Selective dependence of H2-M3-restricted CD8 responses on IL-15Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes.The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis.Paracrine and transpresentation functions of IL-15 are mediated by diverse splice versions of IL-15Rα in human monocytes and dendritic cellsPotential effector and immunoregulatory functions of mast cells in mucosal immunity.Approaches for analyzing the roles of mast cells and their proteases in vivo.Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis.Signalling, inflammation and arthritis: Crossed signals: the role of interleukin-15 and -18 in autoimmunity.IL-15 functions as a danger signal to regulate tissue-resident T cells and tissue destructionRole and relevance of mast cells in fungal infectionsNovel identified receptors on mast cells.Mast cells: multitalented facilitators of protection against bacterial pathogens.Mast cells and basophils in cutaneous immune responses.How a cytokine is chaperoned through the secretory pathway by complexing with its own receptor: lessons from interleukin-15 (IL-15)/IL-15 receptor alpha.Mast cells aggravate sepsis by inhibiting peritoneal macrophage phagocytosis.Systemic mast cell degranulation increases mortality during polymicrobial septic peritonitis in mice.Transcriptional regulation of mouse mast cell protease-2 by interleukin-15.Mast Cell Chymase Decreases The Severity Of Group B Streptococcus Infections.Mast cell IL-6 improves survival from Klebsiella pneumonia and sepsis by enhancing neutrophil killing.Mast cells impair host defense during murine Streptococcus pneumoniae pneumonia.Heparan sulfate 6-O-sulfotransferase isoform-dependent regulatory effects of heparin on the activities of various proteases in mast cells and the biosynthesis of 6-O-sulfated heparin.Mast Cells Limit the Exacerbation of Chronic Allergic Contact Dermatitis in Response to Repeated Allergen Exposure.Antibiotics with Interleukin-15 inhibition reduces joint inflammation and bone erosions but not cartilage destruction in Staphylococcus aureus-induced arthritis.
P2860
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P2860
IL-15 constrains mast cell-dependent antibacterial defenses by suppressing chymase activities.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
IL-15 constrains mast cell-dep ...... uppressing chymase activities.
@en
IL-15 constrains mast cell-dep ...... uppressing chymase activities.
@nl
type
label
IL-15 constrains mast cell-dep ...... uppressing chymase activities.
@en
IL-15 constrains mast cell-dep ...... uppressing chymase activities.
@nl
prefLabel
IL-15 constrains mast cell-dep ...... uppressing chymase activities.
@en
IL-15 constrains mast cell-dep ...... uppressing chymase activities.
@nl
P2093
P356
P1433
P1476
IL-15 constrains mast cell-dep ...... uppressing chymase activities.
@en
P2093
Elena Bulanova
Ernst Brandt
Farhad Mirghomizadeh
Florian Schiemann
Jan Schulmistrat
Julien Giron-Michel
Marcus Maurer
Natalia Nashkevich
Silvia Bulfone-Paus
Vadim Budagian
P2888
P304
P356
10.1038/NM1615
P407
P577
2007-07-22T00:00:00Z