The anti-apoptotic gene BCL2A1 is a novel transcriptional target of PU.1.
about
A1/Bfl-1 in leukocyte development and cell deathPU.1 is linking the glycolytic enzyme HK3 in neutrophil differentiation and survival of APL cells.BCL2A1a over-expression in murine hematopoietic stem and progenitor cells decreases apoptosis and results in hematopoietic transformation.CLEC5A (MDL-1) is a novel PU.1 transcriptional target during myeloid differentiation.Low DICER1 expression is associated with attenuated neutrophil differentiation and autophagy of NB4 APL cells.The C-terminal domain of A1/Bfl-1 regulates its anti-inflammatory function in human endothelial cellsBCL2A1: the underdog in the BCL2 family.The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL.The anti-apoptotic Bcl-2 family protein A1/Bfl-1 regulates neutrophil survival and homeostasis and is controlled via PI3K and JAK/STAT signaling.PU.1 supports TRAIL-induced cell death by inhibiting NF-κB-mediated cell survival and inducing DR5 expression.Differential effects of Vav-promoter-driven overexpression of BCLX and BFL1 on lymphocyte survival and B cell lymphomagenesis.
P2860
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P2860
The anti-apoptotic gene BCL2A1 is a novel transcriptional target of PU.1.
description
2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
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2010年學術文章
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2010年學術文章
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name
The anti-apoptotic gene BCL2A1 is a novel transcriptional target of PU.1.
@en
The anti-apoptotic gene BCL2A1 is a novel transcriptional target of PU.1.
@nl
type
label
The anti-apoptotic gene BCL2A1 is a novel transcriptional target of PU.1.
@en
The anti-apoptotic gene BCL2A1 is a novel transcriptional target of PU.1.
@nl
prefLabel
The anti-apoptotic gene BCL2A1 is a novel transcriptional target of PU.1.
@en
The anti-apoptotic gene BCL2A1 is a novel transcriptional target of PU.1.
@nl
P2093
P2860
P356
P1433
P1476
The anti-apoptotic gene BCL2A1 is a novel transcriptional target of PU.1.
@en
P2093
P2860
P2888
P304
P356
10.1038/LEU.2010.26
P577
2010-03-04T00:00:00Z