Structural and functional characterization of an essential RTX subdomain of Bordetella pertussis adenylate cyclase toxin.
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Pertussis toxin and adenylate cyclase toxin: key virulence factors of Bordetella pertussis and cell biology toolsRTX proteins: a highly diverse family secreted by a common mechanismBacillus anthracis edema factor substrate specificity: evidence for new modes of actionStructural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretionA calcium-gated lid and a large beta-roll sandwich are revealed by the crystal structure of extracellular lipase from Serratia marcescensCrystal Structure and Biophysical Properties of Bacillus subtilis BdbD: AN OXIDIZING THIOL:DISULFIDE OXIDOREDUCTASE CONTAINING A NOVEL METAL SITEDisorder-to-order transition in the CyaA toxin RTX domain: implications for toxin secretionCharge-dependent secretion of an intrinsically disordered protein via the autotransporter pathway.Fine Epitope Mapping of Two Antibodies Neutralizing the Bordetella Adenylate Cyclase Toxin.The Bordetella adenylate cyclase repeat-in-toxin (RTX) domain is immunodominant and elicits neutralizing antibodies.Structural features of the Pseudomonas fluorescens biofilm adhesin LapA required for LapG-dependent cleavage, biofilm formation, and cell surface localizationCalcium-induced folding and stabilization of the intrinsically disordered RTX domain of the CyaA toxinCalcium, acylation, and molecular confinement favor folding of Bordetella pertussis adenylate cyclase CyaA toxin into a monomeric and cytotoxic formStructural Characterization of Humanized Nanobodies with Neutralizing Activity against the Bordetella pertussis CyaA-Hemolysin: Implications for a Potential Epitope of Toxin-Protective AntigenFunctional Contributions of Positive Charges in the Pore-Lining Helix 3 of the Bordetella pertussis CyaA-Hemolysin to Hemolytic Activity and Ion-Channel Opening.Mutual effects of disorder and order in fusion proteins between intrinsically disordered domains and fluorescent proteins.Phospholipase A activity of adenylate cyclase toxin mediates translocation of its adenylate cyclase domain.Rearranging and concatenating a native RTX domain to understand sequence modularity.Bordetella pertussis adenylate cyclase toxin (ACT) induces cyclooxygenase-2 (COX-2) in murine macrophages and is facilitated by ACT interaction with CD11b/CD18 (Mac-1).Block V RTX Domain of Adenylate Cyclase from Bordetella pertussis: A Conformationally Dynamic Scaffold for Protein Engineering Applications.Stability, structural and functional properties of a monomeric, calcium-loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis.Identification and analysis of four candidate symbiosis genes from 'Chlorochromatium aggregatum', a highly developed bacterial symbiosis.Calcium-induced folding of intrinsically disordered repeat-in-toxin (RTX) motifs via changes of protein charges and oligomerization states.Characterization of a membrane-active peptide from the Bordetella pertussis CyaA toxin.Structure-Function Relationships Underlying the Capacity of Bordetella Adenylate Cyclase Toxin to Disarm Host Phagocytes.RTX calcium binding motifs are intrinsically disordered in the absence of calcium: implication for protein secretion.Understanding the Mechanism of Translocation of Adenylate Cyclase Toxin across Biological Membranes.Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region.Bacterial Translocation Ratchets: Shared Physical Principles with Different Molecular Implementations: How bacterial secretion systems bias Brownian motion for efficient translocation of macromolecules.The calcium-binding C-terminal domain of Escherichia coli alpha-hemolysin is a major determinant in the surface-active properties of the protein.Membrane localization of the Repeats-in-Toxin (RTX) Leukotoxin (LtxA) produced by Aggregatibacter actinomycetemcomitans
P2860
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P2860
Structural and functional characterization of an essential RTX subdomain of Bordetella pertussis adenylate cyclase toxin.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Structural and functional char ...... ussis adenylate cyclase toxin.
@en
Structural and functional char ...... ussis adenylate cyclase toxin.
@nl
type
label
Structural and functional char ...... ussis adenylate cyclase toxin.
@en
Structural and functional char ...... ussis adenylate cyclase toxin.
@nl
prefLabel
Structural and functional char ...... ussis adenylate cyclase toxin.
@en
Structural and functional char ...... ussis adenylate cyclase toxin.
@nl
P2093
P2860
P50
P356
P1476
Structural and functional char ...... ussis adenylate cyclase toxin.
@en
P2093
Alain Chaffotte
Christophe Bodenreider
Cécile Bauche
Oliver Knapp
P2860
P304
16914-16926
P356
10.1074/JBC.M601594200
P407
P577
2006-04-20T00:00:00Z