Imatinib attenuates hypoxia-induced pulmonary arterial hypertension pathology via reduction in 5-hydroxytryptamine through inhibition of tryptophan hydroxylase 1 expression.
about
5-HT2B receptor antagonists inhibit fibrosis and protect from RV heart failureMicroRNA-140-5p and SMURF1 regulate pulmonary arterial hypertension.Identification of a Novel Allosteric Inhibitory Site on Tryptophan Hydroxylase 1 Enabling Unprecedented Selectivity Over all Related HydroxylasesUpdate in pulmonary vascular diseases 2013.PK10453, a nonselective platelet-derived growth factor receptor inhibitor, prevents the progression of pulmonary arterial hypertension.Serotonin Signaling Through the 5-HT1B Receptor and NADPH Oxidase 1 in Pulmonary Arterial Hypertension.Sex affects bone morphogenetic protein type II receptor signaling in pulmonary artery smooth muscle cells.Imatinib attenuates cardiac fibrosis by inhibiting platelet-derived growth factor receptors activation in isoproterenol induced model.Signal transduction in the development of pulmonary arterial hypertensionGender, sex hormones and pulmonary hypertension.Calpain-2 activates Akt via TGF-β1-mTORC2 pathway in pulmonary artery smooth muscle cellsGenotype-phenotype effects of Bmpr2 mutations on disease severity in mouse models of pulmonary hypertension.Bromodomain and extra-terminal protein mimic JQ1 decreases inflammation in human vascular endothelial cells: Implications for pulmonary arterial hypertension.Pulmonary arterial hypertension: basis of sex differences in incidence and treatment response.Cardiovascular safety of tyrosine kinase inhibitors: with a special focus on cardiac repolarisation (QT interval).Inhaled tyrosine kinase inhibitors for pulmonary hypertension: a possible future treatment.The first Keystone Symposia Conference on pulmonary vascular isease and right ventricular dysfunction: Current concepts and future therapies.Elevated transglutaminase 2 activity is associated with hypoxia-induced experimental pulmonary hypertension in mice.Serotonin transporter is not required for the development of severe pulmonary hypertension in the Sugen hypoxia rat model.Beneficial effects of platelet-derived growth factor on hemorrhagic shock in rats and the underlying mechanisms.Reduction of endoplasmic reticulum stress by 4-phenylbutyric acid prevents the development of hypoxia-induced pulmonary arterial hypertension.Are tyrosine kinase inhibitors the better serotonin inhibitors?The serotonin hypothesis in pulmonary hypertension revisited: targets for novel therapies (2017 Grover Conference Series).Inhibition of Shp2 ameliorates monocrotaline-induced pulmonary arterial hypertension in rats
P2860
Q21284504-5856FA1C-7831-44B9-9C9D-BD447F3B51D6Q32884516-9FBD75B7-F315-49DA-B783-2BC81DB2C110Q33639498-360C32A9-C3AD-40D8-A918-8A3E9D9412A8Q33732209-C7677B3F-E84D-4B3F-859B-11E53FDA754CQ33805920-DADB9276-F167-4845-87F5-0F7FF8F92C40Q33817590-52802AD1-DDC9-410A-9C1F-FC5751AA3207Q35262038-BE4DF8DB-9F2C-441D-BB3B-592DAE0A0D49Q36389384-A24320A2-82EF-4562-B991-8347C24CB2A0Q37133785-78164163-BCBE-4E37-97E1-7AA3060F96A2Q37133789-C139A5A5-4973-4E15-8151-FE6A98CCA525Q37139375-1D9B5F53-8521-422B-BEAB-3BE9B4501021Q37555347-7FAF84C6-E15C-473E-A684-9C8D0EDC4158Q37561236-A0D80424-42C5-412F-ADA8-D92072FB0831Q37671277-0CF71BE1-98AB-4E81-9CBE-891A6A53F028Q38101883-2CD56C74-4FB3-40C7-B41B-8E64A9E7CF01Q39109514-3FA86EFD-B61C-45E2-84B7-98CC6F3A2575Q39353707-E7959807-AC23-416D-BBA8-18A106E31F5EQ41968228-0989C098-205E-4DA1-AF8F-096EAD1F8F20Q45019387-3EB62E1F-85AA-4A4D-A66F-EA70E08C39F4Q54326231-52616197-250C-4098-A8DF-C7A0D1D9AED9Q54370056-4A172C23-2C56-4A01-BA4E-9573E87CB4C6Q54460076-AA212FC2-E41F-4941-910C-A7313307F7D0Q55394065-9973B89D-2206-4777-90B8-D6AC699E6895Q58797618-C9AB8117-2E07-43E9-9F57-10D64E56A07C
P2860
Imatinib attenuates hypoxia-induced pulmonary arterial hypertension pathology via reduction in 5-hydroxytryptamine through inhibition of tryptophan hydroxylase 1 expression.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Imatinib attenuates hypoxia-in ...... phan hydroxylase 1 expression.
@en
Imatinib attenuates hypoxia-in ...... phan hydroxylase 1 expression.
@nl
type
label
Imatinib attenuates hypoxia-in ...... phan hydroxylase 1 expression.
@en
Imatinib attenuates hypoxia-in ...... phan hydroxylase 1 expression.
@nl
prefLabel
Imatinib attenuates hypoxia-in ...... phan hydroxylase 1 expression.
@en
Imatinib attenuates hypoxia-in ...... phan hydroxylase 1 expression.
@nl
P2093
P2860
P1476
Imatinib attenuates hypoxia-in ...... phan hydroxylase 1 expression.
@en
P2093
Andrew Pearce
David J Rowlands
Gabor Jarai
Ieuan Clay
Irena Konstantinova
John Westwick
Loredana Ciuclan
Margaret R MacLean
Martin J Hussey
Matthew Thomas
P2860
P356
10.1164/RCCM.201206-1028OC
P407
P577
2012-10-18T00:00:00Z