Probing the specificity of the subclass B3 FEZ-1 metallo-beta-lactamase by site-directed mutagenesis.
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Structure of Apo- and Monometalated Forms of NDM-1—A Highly Potent Carbapenem-Hydrolyzing Metallo-β-LactamaseStructural Insights into the Subclass B3 Metallo- -Lactamase SMB-1 and the Mode of Inhibition by the Common Metallo- -Lactamase Inhibitor MercaptoacetateCrystal Structure of the Mobile Metallo- -Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the Role of Gln157Trapping and characterization of a reaction intermediate in carbapenem hydrolysis by B. cereus metallo-beta-lactamase.Interaction of Avibactam with Class B Metallo-β-Lactamases.An altered zinc-binding site confers resistance to a covalent inactivator of New Delhi metallo-beta-lactamase-1 (NDM-1) discovered by high-throughput screeningProbing the role of Met221 in the unusual metallo-β-lactamase GOB-18.Insights into an evolutionary strategy leading to antibiotic resistance.A variety of roles for versatile zinc in metallo-β-lactamases.Structural and Biochemical Characterization of Rm3, a Subclass B3 Metallo-β-Lactamase Identified from a Functional Metagenomic Study.Danger lurking in the "unknowns": structure-to-function studies of hypothetical protein Bleg1_2437 from Bacillus lehensis G1 alkaliphile revealed an evolutionary divergent B3 metallo-beta-lactamase.Role of zinc content on the catalytic efficiency of B1 metallo beta-lactamases.Covalent inhibition of New Delhi metallo-β-lactamase-1 (NDM-1) by cefaclor.In vivo impact of Met221 substitution in GOB metallo-β-lactamase.Zinc- and iron-dependent cytosolic metallo-beta-lactamase domain proteins exhibit similar zinc-binding affinities, independent of an atypical glutamate at the metal-binding site.
P2860
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P2860
Probing the specificity of the subclass B3 FEZ-1 metallo-beta-lactamase by site-directed mutagenesis.
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2004 nî lūn-bûn
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2004年学术文章
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2004年学术文章
@zh-my
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name
Probing the specificity of the ...... by site-directed mutagenesis.
@en
Probing the specificity of the ...... by site-directed mutagenesis.
@nl
type
label
Probing the specificity of the ...... by site-directed mutagenesis.
@en
Probing the specificity of the ...... by site-directed mutagenesis.
@nl
prefLabel
Probing the specificity of the ...... by site-directed mutagenesis.
@en
Probing the specificity of the ...... by site-directed mutagenesis.
@nl
P2093
P2860
P356
P1476
Probing the specificity of the ...... e by site-directed mutagenesis
@en
P2093
Iris Thamm
Isabel García-Sáez
Jean-Marie Frère
Jozef Van Beeumen
Kris De Vriendt
Moreno Galleni
Otto Dideberg
Paola Sandra Mercuri
P2860
P304
33630-33638
P356
10.1074/JBC.M403671200
P407
P577
2004-05-24T00:00:00Z