NAD+-glycohydrolase acts as an intracellular toxin to enhance the extracellular survival of group A streptococci.
about
Cholesterol-dependent cytolysins, a family of versatile pore-forming toxinsCytotoxic effects of streptolysin o and streptolysin s enhance the virulence of poorly encapsulated group a streptococciA novel endogenous inhibitor of the secreted streptococcal NAD-glycohydrolase.Structural Basis of Streptococcus pyogenes Immunity to Its NAD+ Glycohydrolase ToxinEmergence of a New Highly Successful Acapsular Group A Streptococcus Clade of Genotype emm89 in the United KingdomA molecular trigger for intercontinental epidemics of group A Streptococcus.The phagosome: compartment with a license to kill.Characterization of a small PlcR-regulated gene co-expressed with cereolysin O.Clindamycin-induced CovS-mediated regulation of the production of virulent exoproteins streptolysin O, NAD glycohydrolase, and streptokinase in Streptococcus pyogenes.NADase as a target molecule of in vivo suppression of the toxicity in the invasive M-1 group A Streptococcal isolates.Characterization of Streptococcus pyogenes beta-NAD+ glycohydrolase: re-evaluation of enzymatic properties associated with pathogenesis.Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences.Inhibition of dendritic cell maturation by group A StreptococcusStreptococcus pyogenes cytolysin-mediated translocation does not require pore formation by streptolysin O.Inhibition of Inflammasome-Dependent Interleukin 1β Production by Streptococcal NAD+-Glycohydrolase: Evidence for Extracellular Activity.Cytolysin-dependent evasion of lysosomal killingVariation in Streptococcus pyogenes NAD+ glycohydrolase is associated with tissue tropism.Induction of endoplasmic reticulum stress and unfolded protein response constitutes a pathogenic strategy of group A streptococcusRole of NADase in virulence in experimental invasive group A streptococcal infection.Streptolysin O and NAD-glycohydrolase prevent phagolysosome acidification and promote group A Streptococcus survival in macrophages.Disease manifestations and pathogenic mechanisms of Group A Streptococcus.A novel cholesterol-insensitive mode of membrane binding promotes cytolysin-mediated translocation by Streptolysin OStreptolysin O and its co-toxin NAD-glycohydrolase protect group A Streptococcus from Xenophagic killing.Structural studies of Streptococcus pyogenes streptolysin O provide insights into the early steps of membrane penetration.SpyA, a C3-like ADP-ribosyltransferase, contributes to virulence in a mouse subcutaneous model of Streptococcus pyogenes infection.Emergence of a bacterial clone with enhanced virulence by acquisition of a phage encoding a secreted phospholipase A2.The Rgg regulator of Streptococcus pyogenes influences utilization of nonglucose carbohydrates, prophage induction, and expression of the NAD-glycohydrolase virulence operon.Counteractive balancing of transcriptome expression involving CodY and CovRS in Streptococcus pyogenes.Host responses to group a streptococcus: cell death and inflammationPhosphorylation events in the multiple gene regulator of group A Streptococcus significantly influence global gene expression and virulenceSerine/threonine phosphatase (SP-STP), secreted from Streptococcus pyogenes, is a pro-apoptotic protein.NAD+-Glycohydrolase Promotes Intracellular Survival of Group A Streptococcus.The Streptococcus pyogenes NAD(+) glycohydrolase modulates epithelial cell PARylation and HMGB1 releaseDual modes of membrane binding direct pore formation by Streptolysin O.Inter- and intraserotypic variation in the Streptococcus pyogenes Rgg regulon.Analysis of polymorphic residues reveals distinct enzymatic and cytotoxic activities of the Streptococcus pyogenes NAD+ glycohydrolase.Regulation of Apoptosis by Gram-Positive Bacteria: Mechanistic Diversity and Consequences for Immunity.Reduction of streptolysin O (SLO) pore-forming activity enhances inflammasome activation.Streptolysin O promotes group A Streptococcus immune evasion by accelerated macrophage apoptosis.Streptococcus adherence and colonization.
P2860
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P2860
NAD+-glycohydrolase acts as an intracellular toxin to enhance the extracellular survival of group A streptococci.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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@zh-sg
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name
NAD+-glycohydrolase acts as an ...... vival of group A streptococci.
@en
NAD+-glycohydrolase acts as an ...... vival of group A streptococci.
@nl
type
label
NAD+-glycohydrolase acts as an ...... vival of group A streptococci.
@en
NAD+-glycohydrolase acts as an ...... vival of group A streptococci.
@nl
prefLabel
NAD+-glycohydrolase acts as an ...... vival of group A streptococci.
@en
NAD+-glycohydrolase acts as an ...... vival of group A streptococci.
@nl
P2093
P2860
P1476
NAD+-glycohydrolase acts as an ...... vival of group A streptococci.
@en
P2093
Angela L Bricker
Cameron D Ashbaugh
Colette Cywes
Michael R Wessels
P2860
P304
P356
10.1046/J.1365-2958.2002.02876.X
P407
P577
2002-04-01T00:00:00Z