Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin.
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Transcriptional regulation by AIRE: molecular mechanisms of central toleranceOsteoimmunology: interactions of the bone and immune systemFOXN1 in thymus organogenesis and developmentControl of the thymic medulla and its influence on αβT-cell developmentA Tale from TGF-β Superfamily for Thymus Ontogeny and FunctionInduction of central tolerance by the factor Aire: molecular and epigenetic regulationThymic epithelial cell development and differentiation: cellular and molecular regulationAdult thymic epithelial cell (TEC) progenitors and TEC stem cells: Models and mechanisms for TEC development and maintenanceAire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-toleranceFoxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergenceMorphogenesis and maintenance of the 3D thymic medulla and prevention of nude skin phenotype require FoxN1 in pre- and post-natal K14 epitheliumPostnatal tissue-specific disruption of transcription factor FoxN1 triggers acute thymic atrophy.Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cellsAdult thymus contains FoxN1(-) epithelial stem cells that are bipotent for medullary and cortical thymic epithelial lineages.Claudin 13, a member of the claudin family regulated in mouse stress induced erythropoiesisEctopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesisThe Antigenic Determinant That Defines Thymic Nurse Cells Is Expressed by Thymic Epithelial Progenitor Cells.Three distinct subsets of thymic epithelial cells in rats and mice defined by novel antibodies.Claudin-4 deficiency results in urothelial hyperplasia and lethal hydronephrosis.Biological significance of FoxN1 gain-of-function mutations during T and B lymphopoiesis in juvenile mice.Serial progression of cortical and medullary thymic epithelial microenvironments.Claudin-4 induction by E-protein activity in later stages of CD4/8 double-positive thymocytes to increase positive selection efficiencyEstablished thymic epithelial progenitor/stem cell-like cell lines differentiate into mature thymic epithelial cells and support T cell development.Enteroendocrine cells are specifically marked by cell surface expression of claudin-4 in mouse small intestine.Abnormalities of thymic stroma may contribute to immune dysregulation in murine models of leaky severe combined immunodeficiency.Central Role of Core Binding Factor β2 in Mucosa-Associated Lymphoid Tissue Organogenesis in MouseIdentification of MiR-205 As a MicroRNA That Is Highly Expressed in Medullary Thymic Epithelial Cells.Requirement of Stat3 Signaling in the Postnatal Development of Thymic Medullary Epithelial Cells.β-catenin activation drives thymoma initiation and progression in miceProliferative arrest and rapid turnover of thymic epithelial cells expressing AireCentral tolerance to self revealed by the autoimmune regulator.Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism.Identification of Plet-1 as a specific marker of early thymic epithelial progenitor cells.Maturation of embryonic tissues in a lymph node: a new approach for bioengineering complex organs.Identification of a Bipotent Epithelial Progenitor Population in the Adult Thymus.Dynamics of thymus organogenesis and colonization in early human developmentDynamic spatio-temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla.Aire-expressing thymic medullary epithelial cells originate from β5t-expressing progenitor cells.Ectopic expression of peripheral-tissue antigens in the thymic epithelium: probabilistic, monoallelic, misinitiatedEarly defects in human T-cell development severely affect distribution and maturation of thymic stromal cells: possible implications for the pathophysiology of Omenn syndrome
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P2860
Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Medullary thymic epithelial ce ...... from cells expressing claudin.
@en
Medullary thymic epithelial ce ...... from cells expressing claudin.
@nl
type
label
Medullary thymic epithelial ce ...... from cells expressing claudin.
@en
Medullary thymic epithelial ce ...... from cells expressing claudin.
@nl
prefLabel
Medullary thymic epithelial ce ...... from cells expressing claudin.
@en
Medullary thymic epithelial ce ...... from cells expressing claudin.
@nl
P2093
P2860
P356
P1433
P1476
Medullary thymic epithelial ce ...... from cells expressing claudin.
@en
P2093
Mitsuru Matsumoto
Nagahiro Minato
Takashi Kobayashi
Yoko Hamazaki
Yongwon Choi
P2860
P2888
P304
P356
10.1038/NI1438
P407
P577
2007-02-04T00:00:00Z
P6179
1012293606