Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin. - Wikidata - awgldk - TriplyDB

Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin.

Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin.

http://www.wikidata.org/entity/Q54558035

about

Transcriptional regulation by AIRE: molecular mechanisms of central tolerance Osteoimmunology: interactions of the bone and immune system FOXN1 in thymus organogenesis and development Control of the thymic medulla and its influence on αβT-cell development A Tale from TGF-β Superfamily for Thymus Ontogeny and Function Induction of central tolerance by the factor Aire: molecular and epigenetic regulation Thymic epithelial cell development and differentiation: cellular and molecular regulation Adult thymic epithelial cell (TEC) progenitors and TEC stem cells: Models and mechanisms for TEC development and maintenance Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence Morphogenesis and maintenance of the 3D thymic medulla and prevention of nude skin phenotype require FoxN1 in pre- and post-natal K14 epithelium Postnatal tissue-specific disruption of transcription factor FoxN1 triggers acute thymic atrophy.Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cells Adult thymus contains FoxN1(-) epithelial stem cells that are bipotent for medullary and cortical thymic epithelial lineages.Claudin 13, a member of the claudin family regulated in mouse stress induced erythropoiesis Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesis The Antigenic Determinant That Defines Thymic Nurse Cells Is Expressed by Thymic Epithelial Progenitor Cells.Three distinct subsets of thymic epithelial cells in rats and mice defined by novel antibodies.Claudin-4 deficiency results in urothelial hyperplasia and lethal hydronephrosis.Biological significance of FoxN1 gain-of-function mutations during T and B lymphopoiesis in juvenile mice.Serial progression of cortical and medullary thymic epithelial microenvironments.Claudin-4 induction by E-protein activity in later stages of CD4/8 double-positive thymocytes to increase positive selection efficiency Established thymic epithelial progenitor/stem cell-like cell lines differentiate into mature thymic epithelial cells and support T cell development.Enteroendocrine cells are specifically marked by cell surface expression of claudin-4 in mouse small intestine.Abnormalities of thymic stroma may contribute to immune dysregulation in murine models of leaky severe combined immunodeficiency.Central Role of Core Binding Factor β2 in Mucosa-Associated Lymphoid Tissue Organogenesis in Mouse Identification of MiR-205 As a MicroRNA That Is Highly Expressed in Medullary Thymic Epithelial Cells.Requirement of Stat3 Signaling in the Postnatal Development of Thymic Medullary Epithelial Cells.β-catenin activation drives thymoma initiation and progression in mice Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire Central tolerance to self revealed by the autoimmune regulator.Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism.Identification of Plet-1 as a specific marker of early thymic epithelial progenitor cells.Maturation of embryonic tissues in a lymph node: a new approach for bioengineering complex organs.Identification of a Bipotent Epithelial Progenitor Population in the Adult Thymus.Dynamics of thymus organogenesis and colonization in early human development Dynamic spatio-temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla.Aire-expressing thymic medullary epithelial cells originate from β5t-expressing progenitor cells.Ectopic expression of peripheral-tissue antigens in the thymic epithelium: probabilistic, monoallelic, misinitiated Early defects in human T-cell development severely affect distribution and maturation of thymic stromal cells: possible implications for the pathophysiology of Omenn syndrome

P2860

Q24648384-AAA9A6FC-1A57-4406-B631-E2A3F73FF189 Q24655113-AEBC7F58-CAF7-4FE0-979B-3BC93223B3A5 Q26744673-0BDE748F-128B-4A41-A52B-F8F95AC5E056 Q26752793-B6287B1A-5844-48D2-8EED-51C046134349 Q26781342-94831C94-9E82-4249-89E8-1CD59FA415C4 Q26784143-6337F095-C9C4-4A9F-8907-E9D2D81AE6D8 Q27004003-9F57E161-DCAF-41FB-8E5E-CB9AB21A7AD3 Q28083721-8047D384-0AD6-41E9-B7AE-B7D0617E6CEC Q28585306-3104CC96-C380-4C7B-A35C-0827EFC95F02 Q28589335-008A1873-D882-4DBF-9D45-A03834DE0E94 Q28594939-4ED6720C-1F2D-4DB9-93B6-5918C7988D81 Q33648539-9E501D71-C919-48C5-9B83-6A1E5D59B9B5 Q33703633-10242B3D-9AA9-433D-B521-034C386DF766 Q34106631-37883D28-8DF0-4CF5-896B-A84DC4E591B8 Q34117451-6DD78AC6-2DD9-4DBF-922B-517826F0181C Q34341624-9CD805D7-5CE2-4B0F-BF8A-291610809BDC Q34372619-701EAD2C-3EA8-490B-A4C0-5D379FBF51CC Q34379591-25D05D41-C903-4B27-B952-2B7CAD8A04BB Q34533526-6FCA26D7-6A05-479C-AB86-18DF35CC335A Q34541625-B671CA4D-FED3-42B4-8C03-C96CA849EE70 Q34617656-29CDEB1B-77AD-4502-AF7A-0920754B8070 Q34652895-1FE96E31-17A0-42F6-BDD3-F8ADB7AFC79E Q35005451-DEB05366-D40E-4358-A874-8A88F9644D3B Q35112967-63DB19EA-7147-4DF3-A26C-7A20C61C29FA Q35147048-FC8D973B-9CDD-4B94-B0D0-FA799257A8D9 Q35636978-BF590936-F79B-4435-9A44-FD994680AFE2 Q35744823-FDD3B530-F995-4A50-9CFB-D988BE0F7112 Q35898840-DF3FB785-7A5B-42EF-9A87-D6B962069514 Q35987257-16F8B6E8-9207-464B-BAE1-5A5E112F31AA Q36229072-C85A10FF-D5C7-4FD2-B97D-FD55BE6F7C9B Q36303674-C6338276-9982-44E7-87A1-A6A473BB1C0D Q36392973-7EDC7BE5-02B7-4439-996C-6ADA7D63E29F Q36458912-1AF2EEE5-60B9-4AFF-A93C-113882936224 Q36571489-8CCAA44D-EEB2-4CA9-BC34-91D3C25005FB Q36762777-1A1B13A0-BCB0-4409-93B3-D9C71AFA0315 Q36783140-E666204D-CA78-41FC-ADDA-7FC0007F24C5 Q36800015-828450B6-DA1A-4565-8FA6-258CA0CBE044 Q36932226-1E97F8DF-A80F-471E-B560-DC9550695DAC Q36949091-7D04DBEF-6322-40F7-B9A0-B7517EE53091 Q37262455-48BCEDEB-C389-40FB-9F06-B062A004E5EC

P2860

Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin.

http://www.wikidata.org/entity/Q54558035

description

2007 nî lūn-bûn

@nan

2007年の論文

@ja

2007年学术文章

@wuu

2007年学术文章

@zh

2007年学术文章

@zh-cn

2007年学术文章

@zh-hans

2007年学术文章

@zh-my

2007年学术文章

@zh-sg

2007年學術文章

@yue

2007年學術文章

@zh-hant

name

Medullary thymic epithelial ce ...... from cells expressing claudin.

@en

Medullary thymic epithelial ce ...... from cells expressing claudin.

@nl

type

label

Medullary thymic epithelial ce ...... from cells expressing claudin.

@en

Medullary thymic epithelial ce ...... from cells expressing claudin.

@nl

prefLabel

Medullary thymic epithelial ce ...... from cells expressing claudin.

@en

Medullary thymic epithelial ce ...... from cells expressing claudin.

@nl

P1433

Q54558035-8EB09265-E014-46BF-B31E-D9FFC2667765

P1476

Q54558035-C4C1A6AC-B5AF-41E4-808F-BFDBC87F12D3

P2093

Q54558035-1CE33AB7-E285-45E4-8F08-0AF444EFEF90

Q54558035-2BA0F199-2A73-4F5D-AA49-AF39C7E97AD4

Q54558035-DA77456D-E960-4185-9D44-393F9771B76E

Q54558035-DC87FA43-A1BC-4577-A9C0-5297A3F8198A

Q54558035-FF5EF615-FDDA-475F-B7AD-C320EBFB183C

P2860

Q54558035-05C3D3BA-6BA0-4F5E-A616-4350DE9B46D4

Q54558035-0677F843-A654-4419-A5E7-9A9D62F18446

Q54558035-08A9F4A0-2E3C-47F9-990F-0DE966A71E66

Q54558035-0B00AF08-E8A1-470A-B69A-E2ACCE002F07

Q54558035-0D74DE51-AD88-4CD7-A4AA-7444EF3A715E

Q54558035-116C6096-6030-4174-AC00-B2CB8023F620

Q54558035-17EF9208-F597-4944-868F-AB45387B4931

Q54558035-1C6008D2-67C1-4AB0-83F6-73DB45909132

Q54558035-24C5E895-69EA-4EC0-ACA5-26B105ECDD6E

Q54558035-2B01AEC2-DA46-4DAF-A14A-6F066EBC6F5F

P2888

Q54558035-DC4BC054-891D-47E3-8DDB-931BB4A1DD70

P304

Q54558035-A52DDAC7-1BE5-4175-8844-21A454C069CD

P31

Q54558035-A698E3F9-3021-4008-B547-B5BD1E718D3B

P356

Q54558035-B9E8F178-49CC-42EF-A0D5-C30CA762E4D1

P407

Q54558035-D7CFB16E-934A-41CF-82B8-6E0AD29172A2

P433

Q54558035-A0C38578-B70F-4E02-9DE0-C44BF2A2D276

P478

Q54558035-3290A8CE-CAC3-4B8A-BF06-0B4D077811F5

P50

Q54558035-DC621022-39EB-42EB-9D09-54C46A0A163D

Q54558035-EB388393-B6B6-4A36-8D95-F35098B6CBE7

P577

Q54558035-0901DD67-A26B-4915-A66A-13747D90FE23

P6179

Q54558035-534B3708-9C56-41D8-8254-B3961B5A8E33

P698

Q54558035-F932858E-32E7-4159-8D3A-4363F6451C5E

P356

P1433

Nature Immunology

P1476

Medullary thymic epithelial ce ...... from cells expressing claudin.

@en

P2093

Mitsuru Matsumoto

http://www.w3.org/2001/XMLSchema#string

Nagahiro Minato

http://www.w3.org/2001/XMLSchema#string

Takashi Kobayashi

http://www.w3.org/2001/XMLSchema#string

Yoko Hamazaki

http://www.w3.org/2001/XMLSchema#string

Yongwon Choi

http://www.w3.org/2001/XMLSchema#string

P2860

An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

Molecular cloning and functional characterization of the receptor for Clostridium perfringens enterotoxin

Positional cloning of the APECED gene

Claudin-based barrier in simple and stratified cellular sheets

Aire deficient mice develop multiple features of APECED phenotype and show altered immune response

Projection of an immunological self shadow within the thymus by the aire protein

Multifunctional strands in tight junctions

TRAF6 is a critical factor for dendritic cell maturation and development

Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice

Dependence of self-tolerance on TRAF6-directed development of thymic stroma

P2888

P304

304-311

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NI1438

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

8

http://www.w3.org/2001/XMLSchema#string

P50

Hamish S. Scott

P577

2007-02-04T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P6179

1012293606

http://www.w3.org/2001/XMLSchema#string

P698

17277780

http://www.w3.org/2001/XMLSchema#string