Cobalamin-dependent methionine synthase is a modular protein with distinct regions for binding homocysteine, methyltetrahydrofolate, cobalamin, and adenosylmethionine.
about
Hyperhomocysteinemia due to methionine synthase deficiency, cblG: structure of the MTR gene, genotype diversity, and recognition of a common mutation, P1173LStructures of the N-terminal modules imply large domain motions during catalysis by methionine synthaseCrystal structure and solution characterization of the activation domain of human methionine synthaseMetal active site elasticity linked to activation of homocysteine in methionine synthasesA disulfide-stabilized conformer of methionine synthase reveals an unexpected role for the histidine ligand of the cobalamin cofactorInsights into the reactivation of cobalamin-dependent methionine synthaseStructure of the cobalamin-binding protein of a putativeO-demethylase fromDesulfitobacterium hafnienseDCB-2Structures of the methyltransferase component of Desulfitobacterium hafniense DCB-2 O-demethylase shed light on methyltetrahydrofolate formationCharacterization of a three-component vanillate O-demethylase from Moorella thermoaceticaTargeted disruption of the methionine synthase gene in miceGenetic disorders of vitamin B12 metabolism: eight complementation groups – eight genesInfluence of cobalamin scarcity on diatom molecular physiology and identification of a cobalamin acquisition proteinHomocysteine.Methanol:coenzyme M methyltransferase from Methanosarcina barkeri -- substitution of the corrinoid harbouring subunit MtaC by free cob(I)alamin.The MetJ regulon in gammaproteobacteria determined by comparative genomics methods.Methionine synthase polymorphisms (MTR 2756 A>G and MTR 2758 C>G) frequencies and distribution in the Jordanian population and their correlation with neural tube defects in the population of the northern part of JordanA nonpyrrolysine member of the widely distributed trimethylamine methyltransferase family is a glycine betaine methyltransferaseMethanol:coenzyme M methyltransferase from Methanosarcina barkeri. Zinc dependence and thermodynamics of the methanol:cob(I)alamin methyltransferase reaction.Spectroscopic study of the cobalamin-dependent methionine synthase in the activation conformation: effects of the Y1139 residue and S-adenosylmethionine on the B12 cofactor.Probing the role of the histidine 759 ligand in cobalamin-dependent methionine synthase.Factors modulating conformational equilibria in large modular proteins: a case study with cobalamin-dependent methionine synthaseBiochemical and EPR-spectroscopic investigation into heterologously expressed vinyl chloride reductive dehalogenase (VcrA) from Dehalococcoides mccartyi strain VS.Isolation, crystallization and preliminary X-ray analysis of a methanol-induced corrinoid protein from Moorella thermoacetica.A method for prediction of the locations of linker regions within large multifunctional proteins, and application to a type I polyketide synthase.Crystallographic studies on B12 binding proteins in eukaryotes and prokaryotes.Ligand trans influence governs conformation in cobalamin-dependent methionine synthaseCobalamin-dependent and cobamide-dependent methyltransferasesA love affair with vitamins.S-methylmethionine metabolism in Escherichia coli.The gene for cobalamin-independent methionine synthase is essential in Candida albicans: a potential antifungal target.Methyladeninylcobamide functions as the cofactor of methionine synthase in a Cyanobacterium, Spirulina platensis NIES-39.Reactivation of methionine synthase from Thermotoga maritima (TM0268) requires the downstream gene product TM0269.Intraprotein transmethylation via a CH3-Co(iii) species in myoglobin reconstituted with a cobalt corrinoid complex.Co+-H interaction inspired alternate coordination geometries of biologically important cob(I)alamin: possible structural and mechanistic consequences for methyltransferases.The energy conserving methyltetrahydromethanopterin:coenzyme M methyltransferase complex from methanogenic archaea: function of the subunit MtrH.A family of S-methylmethionine-dependent thiol/selenol methyltransferases. Role in selenium tolerance and evolutionary relation.Theoretical analysis of C-F bond cleavage mediated by cob[I]alamin-based structures.Mechanistic information on the nitrite-controlled reduction of aquacob(III)alamin by ascorbate at physiological pH.
P2860
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P2860
Cobalamin-dependent methionine synthase is a modular protein with distinct regions for binding homocysteine, methyltetrahydrofolate, cobalamin, and adenosylmethionine.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
Cobalamin-dependent methionine ...... lamin, and adenosylmethionine.
@en
Cobalamin-dependent methionine ...... lamin, and adenosylmethionine.
@nl
type
label
Cobalamin-dependent methionine ...... lamin, and adenosylmethionine.
@en
Cobalamin-dependent methionine ...... lamin, and adenosylmethionine.
@nl
prefLabel
Cobalamin-dependent methionine ...... lamin, and adenosylmethionine.
@en
Cobalamin-dependent methionine ...... lamin, and adenosylmethionine.
@nl
P2093
P356
P1433
P1476
Cobalamin-dependent methionine ...... lamin, and adenosylmethionine.
@en
P2093
C W Goulding
R G Matthews
P304
P356
10.1021/BI9705164
P407
P577
1997-07-01T00:00:00Z