Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations.
about
Chronic lymphocytic leukaemia: an overview of aetiology in light of recent developments in classification and pathogenesisPI3K Signaling in Normal B Cells and Chronic Lymphocytic Leukemia (CLL)Deciphering the molecular landscape in chronic lymphocytic leukemia: time frame of disease evolutionIdentifying High-Risk Chronic Lymphocytic Leukemia: A Pathogenesis-Oriented Appraisal of Prognostic and Predictive Factors in Patients Treated with Chemotherapy with or without ImmunotherapyB-cell receptor signalling and its crosstalk with other pathways in normal and malignant cellsMutation pattern of paired immunoglobulin heavy and light variable domains in chronic lymphocytic leukemia B cellsStereotyped patterns of B-cell receptor in splenic marginal zone lymphomaStereotypical chronic lymphocytic leukemia B-cell receptors recognize survival promoting antigens on stromal cells.Integrating multiple immunogenetic data sources for feature extraction and mining somatic hypermutation patterns: the case of "towards analysis" in chronic lymphocytic leukaemia.Cellular origin(s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities.A new piece to the stereotypy "puzzle" in chronic lymphocytic leukemia.Characterization of structurally defined epitopes recognized by monoclonal antibodies produced by chronic lymphocytic leukemia B cells.Identification of a 20-gene expression-based risk score as a predictor of clinical outcome in chronic lymphocytic leukemia patients.Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemiaMany chronic lymphocytic leukemia antibodies recognize apoptotic cells with exposed nonmuscle myosin heavy chain IIA: implications for patient outcome and cell of originClinical laboratory analysis of immunoglobulin heavy chain variable region genes for chronic lymphocytic leukemia prognosis.B-cell receptor epitope recognition correlates with the clinical course of chronic lymphocytic leukemia.Biologic and clinical significance of molecular profiling in Chronic Lymphocytic Leukemia.Relevance of stereotyped B-cell receptors in the context of the molecular, cytogenetic and clinical features of chronic lymphocytic leukemia.Exploiting biological diversity and genomic aberrations in chronic lymphocytic leukemia.High-density screening reveals a different spectrum of genomic aberrations in chronic lymphocytic leukemia patients with 'stereotyped' IGHV3-21 and IGHV4-34 B-cell receptors.Clonotypic analysis of immunoglobulin heavy chain sequences in patients with Waldenström's macroglobulinemia: correlation with MYD88 L265P somatic mutation status, clinical features, and outcomeHow I treat CLL up front.Prognostic factors identified three risk groups in the LRF CLL4 trial, independent of treatment allocationProgrammed death-1 and its ligand are novel immunotolerant molecules expressed on leukemic B cells in chronic lymphocytic leukemiaDistinct gene expression profiles in subsets of chronic lymphocytic leukemia expressing stereotyped IGHV4-34 B-cell receptors.Multiparametric analyses of human PBMCs loaded ex vivo with a candidate idiotype vaccine for HCV-related lymphoproliferative disorders.Silenced B-cell receptor response to autoantigen in a poor-prognostic subset of chronic lymphocytic leukemia.IGHV1-69-encoded antibodies expressed in chronic lymphocytic leukemia react with malondialdehyde-acetaldehyde adduct, an immunodominant oxidation-specific epitopePeptides that bind specifically to an antibody from a chronic lymphocytic leukemia clone expressing unmutated immunoglobulin variable region genes.Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerationsIntraclonal cell expansion and selection driven by B cell receptor in chronic lymphocytic leukemia.Targeted next-generation sequencing in chronic lymphocytic leukemia: a high-throughput yet tailored approach will facilitate implementation in a clinical setting.Insulin growth factor 1 receptor expression is associated with NOTCH1 mutation, trisomy 12 and aggressive clinical course in chronic lymphocytic leukaemia.An entity evolving into a community: defining the common ancestor and evolutionary trajectory of chronic lymphocytic leukemia stereotyped subset #4.Toll-like receptor signaling pathway in chronic lymphocytic leukemia: distinct gene expression profiles of potential pathogenic significance in specific subsets of patientsThe novel member of the BCL2 gene family, BCL2L12, is substantially elevated in chronic lymphocytic leukemia patients, supporting its value as a significant biomarker.Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia.Excessive antigen reactivity may underlie the clinical aggressiveness of chronic lymphocytic leukemia stereotyped subset #8.Partial versus productive immunoglobulin heavy locus rearrangements in chronic lymphocytic leukemia: implications for B-cell receptor stereotypy
P2860
Q23917829-688D33D1-7EEA-49F3-BC5A-9C26C9466C51Q26782633-E699A682-6567-4074-854C-ABCFAE33E04CQ26823586-5F647233-80CF-4464-B83A-32197D52AE61Q28077136-0BD18141-BCB4-4A2E-9A23-2BA910793988Q28245018-C4C95925-F040-4276-AB4E-36C0998F5B56Q29048163-1CA04C55-ADF1-43B3-A931-78FCA243B4A8Q29048186-4491788D-8B2B-4F68-ACBE-1E05251694D7Q30994095-7832E320-38FD-4D79-965E-FE33D689F6F4Q31107783-FA8EA5A0-B27F-49EF-8AE3-8DDEA3DA11AFQ33350258-0B143A93-63C6-4D4E-8BAE-1A3411CA14A3Q33361047-5813B6B2-06D9-4956-965F-28FDA6B2E8AAQ33494799-D0A17C39-530B-4999-BA8A-9E8C3D3E1995Q33634389-A4E0EFA7-2922-44C1-9017-594EF2F4AAAEQ33804706-D66E5A28-044E-420E-97BC-33A36C1089E7Q33849548-10F5B277-C651-470E-93E0-D26B50D76E2AQ33856248-EDF9179C-B0D8-4663-B59C-090F08EFFC19Q33878649-E734B5C5-24E0-40B6-B15A-C9EB0A9546B2Q33886052-5A018D08-C47C-49CE-A0E5-BF64F7DB392DQ34012864-8A523917-A522-4253-8AD5-8DCD9E0BE8B5Q34056568-6D34C996-987F-4045-9A38-49871B4FABBFQ34095630-8A590508-488D-4AC6-A0E1-0087D55B90AAQ34101118-BE6045EE-975A-47C8-86B8-6D3FCCE662BEQ34137158-5035542C-6A70-41AE-950B-106A4BD82547Q34166551-75E931D2-D5CA-4879-9569-76B05532D0C1Q34245048-6A02065D-5567-436A-9EAF-C17B56B55BC4Q34371084-683FC8E8-AF2F-4AE2-B112-5D02B958B5D3Q34427560-5E4109C7-8A48-4546-89FA-BC760370C27BQ34463658-9782BBAD-C378-4E37-BFB5-286BFF5FC6FCQ34804388-4F548EAD-DB26-4F9B-97AB-692056003F71Q34901206-300A9669-1EE2-4E37-BD41-265105FEDF81Q35029461-FB86E1A4-05EF-48E0-8D61-0585015499B8Q35136742-1B903DDC-F560-4B6C-B601-ABA59D2844B1Q35146301-BCB8A910-AB07-4B8C-BA9C-1EA91DAC5422Q35192691-3446AB27-BE38-4F4B-8208-4B7E36746DC7Q35434973-AFF29D06-2726-494B-A9A2-8DCDDB52929BQ35528659-592FEA40-CC04-4A8F-B7C5-942614CAE1B1Q35584788-E4F0B6D5-BA45-419C-86CC-9910DB1489D3Q35671227-AA5816A7-EDCB-4BD0-BF22-7A23DB927AF7Q35692395-8BEB69E9-60D1-42B3-8631-9054A532ADD9Q35747546-61616F8A-2F6D-405A-9A15-3E4439CAE5AA
P2860
Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Over 20% of patients with chro ...... ons and clinical correlations.
@en
Over 20% of patients with chro ...... ons and clinical correlations.
@nl
type
label
Over 20% of patients with chro ...... ons and clinical correlations.
@en
Over 20% of patients with chro ...... ons and clinical correlations.
@nl
prefLabel
Over 20% of patients with chro ...... ons and clinical correlations.
@en
Over 20% of patients with chro ...... ons and clinical correlations.
@nl
P2093
P50
P921
P1433
P1476
Over 20% of patients with chro ...... ons and clinical correlations.
@en
P2093
Anastasia Hadzidimitriou
Athanasios Fassas
Carol Moreno
Chrysoula Belessi
Emili Montserrat
Federico Caligaris-Cappio
Frédéric Davi
Giuseppe Guida
Guillaume Dighiero
Kostas Stamatopoulos
P304
P356
10.1182/BLOOD-2006-03-012948
P407
P577
2006-09-19T00:00:00Z