Bordetella pertussis adenylate cyclase toxin. Structural and functional independence of the catalytic and hemolytic activities.
about
The adenylate cyclase toxin of Bordetella pertussis binds to target cells via the alpha(M)beta(2) integrin (CD11b/CD18)Pertussis: Microbiology, Disease, Treatment, and Prevention.Bordetella adenylate cyclase toxin interacts with filamentous haemagglutinin to inhibit biofilm formation in vitro.Cyclic AMP-mediated suppression of neutrophil extracellular trap formation and apoptosis by the Bordetella pertussis adenylate cyclase toxin.Characterization of binding of adenylate cyclase toxin to target cells by flow cytometry.Translocation-specific conformation of adenylate cyclase toxin from Bordetella pertussis inhibits toxin-mediated hemolysis.Differences in purinergic amplification of osmotic cell lysis by the pore-forming RTX toxins Bordetella pertussis CyaA and Actinobacillus pleuropneumoniae ApxIA: the role of pore size.Delivery of large heterologous polypeptides across the cytoplasmic membrane of antigen-presenting cells by the Bordetella RTX hemolysin moiety lacking the adenylyl cyclase domain.Selective translocation of the Bordetella pertussis adenylate cyclase toxin across the basolateral membranes of polarized epithelial cellsAdenylate cyclase toxin (ACT) from Bordetella hinzii: characterization and differences from ACT of Bordetella pertussisAdenylate cyclase toxin from Bordetella pertussis synergizes with lipopolysaccharide to promote innate interleukin-10 production and enhances the induction of Th2 and regulatory T cells.CyaC-mediated activation is important not only for toxic but also for protective activities of Bordetella pertussis adenylate cyclase-hemolysin.Induction of neutralizing antibodies and Th1-polarized and CD4-independent CD8+ T-cell responses following delivery of human immunodeficiency virus type 1 Tat protein by recombinant adenylate cyclase of Bordetella pertussis.Suppression of platelet aggregation by Bordetella pertussis adenylate cyclase toxin.Stimulation of Bordetella pertussis adenylate cyclase toxin intoxication by its hemolysin domainBordetella pertussis pathogenesis: current and future challenges.Calcium, acylation, and molecular confinement favor folding of Bordetella pertussis adenylate cyclase CyaA toxin into a monomeric and cytotoxic formThe C-terminal domain is essential for protective activity of the Bordetella pertussis adenylate cyclase-hemolysin.Cell-invasive activity of epitope-tagged adenylate cyclase of Bordetella pertussis allows in vitro presentation of a foreign epitope to CD8+ cytotoxic T cells.Membrane-Pore Forming Characteristics of the Bordetella pertussis CyaA-Hemolysin Domain.RTX cytotoxins recognize beta2 integrin receptors through N-linked oligosaccharidesFunctional Contributions of Positive Charges in the Pore-Lining Helix 3 of the Bordetella pertussis CyaA-Hemolysin to Hemolytic Activity and Ion-Channel Opening.Delivery of CD8(+) T-cell epitopes into major histocompatibility complex class I antigen presentation pathway by Bordetella pertussis adenylate cyclase: delineation of cell invasive structures and permissive insertion sites.Phospholipase A activity of adenylate cyclase toxin mediates translocation of its adenylate cyclase domain.GtxA from Gallibacterium anatis, a cytolytic RTX-toxin with a novel domain organisation.Stability, structural and functional properties of a monomeric, calcium-loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis.Characterization of a membrane-active peptide from the Bordetella pertussis CyaA toxin.
P2860
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P2860
Bordetella pertussis adenylate cyclase toxin. Structural and functional independence of the catalytic and hemolytic activities.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh-hant
name
Bordetella pertussis adenylate ...... ytic and hemolytic activities.
@en
Bordetella pertussis adenylate ...... ytic and hemolytic activities.
@nl
type
label
Bordetella pertussis adenylate ...... ytic and hemolytic activities.
@en
Bordetella pertussis adenylate ...... ytic and hemolytic activities.
@nl
prefLabel
Bordetella pertussis adenylate ...... ytic and hemolytic activities.
@en
Bordetella pertussis adenylate ...... ytic and hemolytic activities.
@nl
P2093
P1476
Bordetella pertussis adenylate ...... ytic and hemolytic activities.
@en
P2093
P304
13598-13602
P407
P577
1992-07-01T00:00:00Z