Comparative dose-effect relations at several dosing intervals for beta-lactam, aminoglycoside and quinolone antibiotics against gram-negative bacilli in murine thigh-infection and pneumonitis models.
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Novel Bacterial NAD+-Dependent DNA Ligase Inhibitors with Broad-Spectrum Activity and Antibacterial Efficacy In VivoEfficacy of ceftriaxone and gentamicin given once a day by using human-like pharmacokinetics in treatment of experimental staphylococcal endocarditis.Efficacy of trovafloxacin against penicillin-susceptible and multiresistant strains of Streptococcus pneumoniae in a mouse pneumonia model.Pharmacodynamics of fluconazole in a murine model of systemic candidiasis.Pharmacodynamics of daptomycin in a murine thigh model of Staphylococcus aureus infection.Improved efficacy of ciprofloxacin administered in polyethylene glycol-coated liposomes for treatment of Klebsiella pneumoniae pneumonia in rats.Determination of antibiotic effect in an in vitro pharmacodynamic model: comparison with an established animal model of infectionIn vivo activity of cefquinome against Escherichia coli in the thighs of neutropenic miceQuinolone efflux pumps play a central role in emergence of fluoroquinolone resistance in Streptococcus pneumoniae.Nonlinear pharmacokinetics of piperacillin in healthy volunteers--implications for optimal dosage regimensIn vitro and in vivo pharmacokinetics-pharmacodynamics of GV143253A, a novel trinem.Ceftaroline versus ceftriaxone in a highly penicillin-resistant pneumococcal pneumonia rabbit model using simulated human dosing.Pharmacodynamics of S-3578, a novel cephem, in murine lung and systemic infection modelsContinuous infusion of beta-lactam antibioticsPharmacodynamics of levofloxacin and ciprofloxacin in a murine pneumonia model: peak concentration/MIC versus area under the curve/MIC ratios.Pharmacodynamics of a fluoroquinolone antimicrobial agent in a neutropenic rat model of Pseudomonas sepsisDose ranging and fractionation of intravenous ciprofloxacin against Pseudomonas aeruginosa and Staphylococcus aureus in an in vitro model of infection.Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapy.Correlation between in vitro and in vivo activity of antimicrobial agents against gram-negative bacilli in a murine infection model.Management of meningitis due to antibiotic-resistant Acinetobacter species.Pharmacodynamic profiling of piperacillin in the presence of tazobactam in patients through the use of population pharmacokinetic models and Monte Carlo simulation.Use of Monte Carlo simulations to select therapeutic doses and provisional breakpoints of BAL9141.Efficacy of novel rifamycin derivatives against rifamycin-sensitive and -resistant Staphylococcus aureus isolates in murine models of infectionEfficacy of teicoplanin-gentamicin given once a day on the basis of pharmacokinetics in humans for treatment of enterococcal experimental endocarditisComparisons between antimicrobial pharmacodynamic indices and bacterial killing as described by using the Zhi modelPharmacokinetics (PK), pharmacodynamics (PD), and PK-PD integration of danofloxacin in sheep biological fluids.Effect of gentamicin dosing interval on therapy of viridans streptococcal experimental endocarditis with gentamicin plus penicillinTwenty-four-hour area under the concentration-time curve/MIC ratio as a generic predictor of fluoroquinolone antimicrobial effect by using three strains of Pseudomonas aeruginosa and an in vitro pharmacodynamic model.In vivo efficacy of the novel aminoglycoside ACHN-490 in murine infection modelsEffect of treatment duration on pharmacokinetic/pharmacodynamic indices correlating with therapeutic efficacy of ceftazidime in experimental Klebsiella pneumoniae lung infection.
P2860
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P2860
Comparative dose-effect relations at several dosing intervals for beta-lactam, aminoglycoside and quinolone antibiotics against gram-negative bacilli in murine thigh-infection and pneumonitis models.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年学术文章
@wuu
1990年学术文章
@zh-cn
1990年学术文章
@zh-hans
1990年学术文章
@zh-my
1990年学术文章
@zh-sg
1990年學術文章
@yue
1990年學術文章
@zh
1990年學術文章
@zh-hant
name
Comparative dose-effect relati ...... ection and pneumonitis models.
@en
Comparative dose-effect relati ...... ection and pneumonitis models.
@nl
type
label
Comparative dose-effect relati ...... ection and pneumonitis models.
@en
Comparative dose-effect relati ...... ection and pneumonitis models.
@nl
prefLabel
Comparative dose-effect relati ...... ection and pneumonitis models.
@en
Comparative dose-effect relati ...... ection and pneumonitis models.
@nl
P2093
P1476
Comparative dose-effect relati ...... ection and pneumonitis models.
@en
P2093
P304
P577
1990-01-01T00:00:00Z