about
Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's diseaseIron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's diseaseN-methyl D-aspartate (NMDA) receptor antagonists and memantine treatment for Alzheimer's disease, vascular dementia and Parkinson's diseaseAlzheimer's disease therapeutics targeted to the control of amyloid precursor protein translation: maintenance of brain iron homeostasisNovel 5' untranslated region directed blockers of iron-regulatory protein-1 dependent amyloid precursor protein translation: implications for down syndrome and Alzheimer's diseaseA review of independent component analysis application to microarray gene expression dataMetal exposure and Alzheimer's pathogenesis.A high-throughput drug screen targeted to the 5'untranslated region of Alzheimer amyloid precursor protein mRNA.Independent component analysis of Alzheimer's DNA microarray gene expression dataThe alpha-synuclein 5'untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen.Redox-active metals, oxidative stress, and Alzheimer's disease pathology.Differential Expression of the Activator Protein 1 Transcription Factor Regulates Interleukin-1ß Induction of Interleukin 6 in the Developing Enterocyte.Physiological and pathological role of alpha-synuclein in Parkinson's disease through iron mediated oxidative stress; the role of a putative iron-responsive elementThe role of T cells in osteoporosis, an update.Novel drug targets based on metallobiology of Alzheimer's disease.Brain Iron Metabolism Dysfunction in Parkinson's Disease.Parkinson's disease iron deposition caused by nitric oxide-induced loss of β-amyloid precursor protein.A role for amyloid precursor protein translation to restore iron homeostasis and ameliorate lead (Pb) neurotoxicity.Interleukin-1alpha stimulates non-amyloidogenic pathway by alpha-secretase (ADAM-10 and ADAM-17) cleavage of APP in human astrocytic cells involving p38 MAP kinase.Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis.L-arginine and Alzheimer's disease.An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript.Pilot study of the reducing effect on amyloidosis in vivo by three FDA pre-approved drugs via the Alzheimer's APP 5' untranslated region.RNA therapeutics directed to the non coding regions of APP mRNA, in vivo anti-amyloid efficacy of paroxetine, erythromycin, and N-acetyl cysteine.Assessments of plasma ghrelin levels in the early stages of parkinson's disease.S-Adenosyl Methionine and Transmethylation Pathways in Neuropsychiatric Diseases Throughout Life.Alzheimer's disease drug discovery targeted to the APP mRNA 5'untranslated region.
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description
researcher
@en
wetenschapper
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հետազոտող
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name
Jack T Rogers
@ast
Jack T Rogers
@en
Jack T Rogers
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Jack T Rogers
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Jack T Rogers
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type
label
Jack T Rogers
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Jack T Rogers
@en
Jack T Rogers
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Jack T Rogers
@nl
Jack T Rogers
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altLabel
Jack Rogers
@en
prefLabel
Jack T Rogers
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Jack T Rogers
@en
Jack T Rogers
@es
Jack T Rogers
@nl
Jack T Rogers
@sl
P106
P31
P496
0000-0003-1262-8578