Loss of CENP-F Results in Dilated Cardiomyopathy with Severe Disruption of Cardiac Myocyte Architecture.

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Loss of CENP-F Results in Dilated Cardiomyopathy with Severe Disruption of Cardiac Myocyte Architecture.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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Loss of CENP-F Results in Dila ...... Cardiac Myocyte Architecture.

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Loss of CENP-F Results in Dila ...... Cardiac Myocyte Architecture.

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Loss of CENP-F Results in Dila ...... Cardiac Myocyte Architecture.

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Loss of CENP-F Results in Dila ...... Cardiac Myocyte Architecture.

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Loss of CENP-F Results in Dila ...... Cardiac Myocyte Architecture.

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Loss of CENP-F Results in Dila ...... Cardiac Myocyte Architecture.

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P1476

Loss of CENP-F Results in Dila ...... Cardiac Myocyte Architecture.

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P2093

Alison K Schroer

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Annabelle Manalo

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David M Bader

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Dylan T Burnette

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John Coogan

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Tanner Brolsma

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Zoe Shancer

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P2860

Silencing mitosin induces misaligned chromosomes, premature chromosome decondensation before anaphase onset, and mitotic cell death.

Farnesylation of Cenp-F is required for G2/M progression and degradation after mitosis

CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis

The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes

Cenp-F links kinetochores to Ndel1/Nde1/Lis1/dynein microtubule motor complexes

Mitosin/CENP-F is a conserved kinetochore protein subjected to cytoplasmic dynein-mediated poleward transport

Murine CENP-F regulates centrosomal microtubule nucleation and interacts with Hook2 at the centrosome

Taxol suppresses dynamics of individual microtubules in living human tumor cells

Mitochondrial Cardiomyopathies

Loss of CENP-F results in distinct microtubule-related defects without chromosomal abnormalities.

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7546

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scholarly article

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10.1038/S41598-018-25774-1

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English

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Aidan Fenix

W David Merryman

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2018-05-15T00:00:00Z

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29765066

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5953941

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