about
A humanin derivative, S14G-HN, prevents amyloid-beta-induced memory impairment in mice.Humanin: after the discovery.Neuroprotection against neurodegenerative diseases: development of a novel hybrid neuroprotective peptide Colivelin.A novel peptide, colivelin, prevents alcohol-induced apoptosis in fetal brain of C57BL/6 mice: signaling pathway investigations.Targeting the JAK2/STAT3 axis in Alzheimer's disease.Expression of reprogramming factors in breast cancer cell lines and the regulation by activated Stat3.Transforming growth factor beta2 autocrinally mediates neuronal cell death induced by amyloid-beta.Development of a femtomolar-acting humanin derivative named colivelin by attaching activity-dependent neurotrophic factor to its N terminus: characterization of colivelin-mediated neuroprotection against Alzheimer's disease-relevant insults in vitroNeuroprotective effect of activity-dependent neurotrophic factor against toxicity from familial amyotrophic lateral sclerosis-linked mutant SOD1 in vitro and in vivo.Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death.Two serine residues distinctly regulate the rescue function of Humanin, an inhibiting factor of Alzheimer's disease-related neurotoxicity: functional potentiation by isomerization and dimerization.The cytoplasmic domain of Alzheimer's amyloid-beta protein precursor causes sustained apoptosis signal-regulating kinase 1/c-Jun NH2-terminal kinase-mediated neurotoxic signal via dimerization.Targeted introduction of V642I mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice.Cell-based in vivo dual imaging probes using genetically expressed tags and chemical contrast agents.D-Ser-containing humanin shows promotion of fibril formation.Amyloid-beta causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons.Stat3 inhibition in neural lineage cells.Colivelin prolongs survival of an ALS model mouse
P50
Q33984646-5CFB98E9-3F2E-4144-9F0A-891B5C065737Q36012082-32FFC95C-E1CE-4525-A2B0-22AB18B25CC2Q36829280-23926476-5B00-4B41-AA4C-C048B1D5EA16Q37441352-6FCE0B09-1D3D-4221-A52C-CA0446F01263Q37575545-43F16673-48BE-44CC-897A-A233D8706FA1Q39339985-4E9DB7CD-5E31-4769-A272-E6FA06540FEFQ40309626-8FBAECAF-A0D1-4C22-9F51-2F634456645DQ40355185-B50DC79E-8557-42D2-AB71-B61C31657700Q40505279-9BB93A52-883D-45B9-9838-C4FE4A3B0608Q44299710-14CE86BD-3F9F-4CD4-BF2C-D95A40ACE4D0Q44465694-69DF6281-EB41-4BB9-8AC9-2440439F8FE2Q44493507-E8936408-33D8-423F-8E2F-178FB7EB352FQ44898890-8338FDDB-9AF6-437A-A891-B8A84405A34DQ45945028-D5E76A29-13E4-4279-99C2-65C759C61C35Q46255775-B4CE5394-96E5-4C3E-9A48-4C7E0CDDBF53Q46350343-5F4A3F6F-8BC3-4F27-B4B3-CE2C68A06471Q52306055-B071AB9B-098F-44EC-8B06-1BBF8EB2EAE0Q82967207-F5C831E5-19F0-4AC4-B308-11F20D734F04
P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Tomohiro Chiba
@ast
Tomohiro Chiba
@en
Tomohiro Chiba
@es
Tomohiro Chiba
@nl
Tomohiro Chiba
@sl
type
label
Tomohiro Chiba
@ast
Tomohiro Chiba
@en
Tomohiro Chiba
@es
Tomohiro Chiba
@nl
Tomohiro Chiba
@sl
prefLabel
Tomohiro Chiba
@ast
Tomohiro Chiba
@en
Tomohiro Chiba
@es
Tomohiro Chiba
@nl
Tomohiro Chiba
@sl
P106
P1153
8057013600
P31
P496
0000-0003-4374-9997