Modulation of GSK-3 provides cellular and functional neuroprotection in the rd10 mouse model of retinitis pigmentosa.

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Modulation of GSK-3 provides cellular and functional neuroprotection in the rd10 mouse model of retinitis pigmentosa.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年學術文章

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Modulation of GSK-3 provides c ...... model of retinitis pigmentosa.

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Modulation of GSK-3 provides c ...... model of retinitis pigmentosa.

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label

Modulation of GSK-3 provides c ...... model of retinitis pigmentosa.

@en

Modulation of GSK-3 provides c ...... model of retinitis pigmentosa.

@nl

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Modulation of GSK-3 provides c ...... model of retinitis pigmentosa.

@en

Modulation of GSK-3 provides c ...... model of retinitis pigmentosa.

@nl

P1476

Modulation of GSK-3 provides c ...... model of retinitis pigmentosa.

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Alonso Sánchez-Cruz

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Beatriz Villarejo-Zori

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Enrique J de la Rosa

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Josefa Zaldivar-Díez

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Miguel Marchena

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Valle Palomo

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P2860

GSK-3 Inhibitors: Preclinical and Clinical Focus on CNS

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Retinitis pigmentosa

The glamour and gloom of glycogen synthase kinase-3

Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3).

Proinsulin binds with high affinity the insulin receptor isoform A and predominantly activates the mitogenic pathway.

Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB.

Inflammatory priming predisposes mice to age-related retinal degeneration.

Small molecules targeting glycogen synthase kinase 3 as potential drug candidates for the treatment of retinitis pigmentosa.

Identification in silico and experimental validation of novel phosphodiesterase 7 inhibitors with efficacy in experimental autoimmune encephalomyelitis mice.

P2888

s13024-018-0251-y

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scholarly article

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10.1186/S13024-018-0251-Y

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P478

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2018-04-16T00:00:00Z

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1103394349

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29661219

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5902946

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