A Computational Approach for Prioritizing Selection of Therapies Targeting Drug Resistant Variation in Anaplastic Lymphoma Kinase.

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A Computational Approach for Prioritizing Selection of Therapies Targeting Drug Resistant Variation in Anaplastic Lymphoma Kinase.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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2018年學術文章

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A Computational Approach for P ...... in Anaplastic Lymphoma Kinase.

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A Computational Approach for P ...... in Anaplastic Lymphoma Kinase.

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A Computational Approach for P ...... in Anaplastic Lymphoma Kinase.

@en

A Computational Approach for P ...... in Anaplastic Lymphoma Kinase.

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A Computational Approach for P ...... in Anaplastic Lymphoma Kinase.

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A Computational Approach for P ...... in Anaplastic Lymphoma Kinase.

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P1476

A Computational Approach for P ...... in Anaplastic Lymphoma Kinase.

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P2093

Matthew D McCoy

http://www.w3.org/2001/XMLSchema#string

Subha Madhavan

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P2860

The Protein Data Bank

DrugBank 4.0: shedding new light on drug metabolism

Cell signaling by receptor tyrosine kinases

Modeling enzyme-ligand binding in drug discovery

Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain

The R1275Q Neuroblastoma Mutant and Certain ATP-competitive Inhibitors Stabilize Alternative Activation Loop Conformations of Anaplastic Lymphoma Kinase

The ALK Inhibitor Ceritinib Overcomes Crizotinib Resistance in Non-Small Cell Lung Cancer

Design of potent and selective inhibitors to overcome clinical anaplastic lymphoma kinase mutations resistant to crizotinib

Discovery of (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a macrocyclic inhibitor of anaplastic lymphoma kinase (ALK) and c

Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor

P304

160-167

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scholarly article

P478

2017

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P577

2018-05-18T00:00:00Z

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P698

29888064

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P932

5961773

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