Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes.
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Novel progesterone receptors: neural localization and possible functionsProgesterone receptor membrane component 1 inhibits the activity of drug-metabolizing cytochromes P450 and binds to cytochrome P450 reductaseProgesterone receptor membrane component-1 (PGRMC1) is the mediator of progesterone's antiapoptotic action in spontaneously immortalized granulosa cells as revealed by PGRMC1 small interfering ribonucleic acid treatment and functional analysis of PGMeasurement of the heme affinity for yeast dap1p, and its importance in cellular functionRegulation of iron homeostasis mediated by the heme-binding protein Dap1 (damage resistance protein 1) via the P450 protein Erg11/Cyp51.A Novel Role for Progesterone Receptor Membrane Component 1 (PGRMC1): A Partner and Regulator of FerrochelataseCalcineurin signaling and membrane lipid homeostasis regulates iron mediated multidrug resistance mechanisms in Candida albicansCYB5D2 requires heme-binding to regulate HeLa cell growth and confer survival from chemotherapeutic agentsOak protein profile alterations upon root colonization by an ectomycorrhizal fungus.Quantitative mass spectrometry of diabetic kidney tubules identifies GRAP as a novel regulator of TGF-beta signaling.The σ2 receptor: a novel protein for the imaging and treatment of cancer.Metabolic response to iron deficiency in Saccharomyces cerevisiae.The 2-Cys peroxiredoxin alkyl hydroperoxide reductase c binds heme and participates in its intracellular availability in Streptococcus agalactiae.Conservation of progesterone hormone function in invertebrate reproduction.Down-regulation of progesterone receptor membrane component 1 (PGRMC1) in peripheral nucleated blood cells associated with premature ovarian failure (POF) and polycystic ovary syndrome (PCOS).Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver.Pgrmc1 (progesterone receptor membrane component 1) associates with epidermal growth factor receptor and regulates erlotinib sensitivity.Role of protein-protein interactions in cytochrome P450-mediated drug metabolism and toxicityS2R(Pgrmc1): the cytochrome-related sigma-2 receptor that regulates lipid and drug metabolism and hormone signaling.New aspects of progesterone interactions with the actin cytoskeleton and neurosteroidogenesis in the cerebellum and the neuronal growth cone.Progesterone receptor membrane component 1 deficiency attenuates growth while promoting chemosensitivity of human endometrial xenograft tumorsThe relationship between follicle development and progesterone receptor membrane component-1 expression in women undergoing in vitro fertilization.Heme utilization in the Caenorhabditis elegans hypodermal cells is facilitated by heme-responsive gene-2.Identification of cytochrome P450 2C2 protein complexes in mouse liver.Neutrophil gelatinase-associated lipocalin (NGAL) expression is dependent on the tumor-associated sigma-2 receptor S2RPgrmc1.Chemical proteomic probes for profiling cytochrome p450 activities and drug interactions in vivo.Cell Models for the Study of Sex Steroid Hormone Neurobiology.One ring to rule them all: trafficking of heme and heme synthesis intermediates in the metazoansProteomic Profiling for Identification of Novel Biomarkers Differentially Expressed in Human Ovaries from Polycystic Ovary Syndrome PatientsProgesterone receptor membrane component-1 regulates hepcidin biosynthesis4-Methyl sterols regulate fission yeast SREBP-Scap under low oxygen and cell stress.The Aspergillus fumigatus Damage Resistance Protein Family Coordinately Regulates Ergosterol Biosynthesis and Azole Susceptibility.Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistanceProgesterone receptor membrane component 1 promotes survival of human breast cancer cells and the growth of xenograft tumors.Breast cancer proteomics reveals correlation between estrogen receptor status and differential phosphorylation of PGRMC1.Influence of protein-protein interactions on the cellular localization of cytochrome P450.Redox compartmentalization in eukaryotic cellsPGRMC1 (progesterone receptor membrane component 1): a targetable protein with multiple functions in steroid signaling, P450 activation and drug binding.Low affinity glucocorticoid binding site ligands as potential anti-fibrogenics.Alterations in the expression, structure and function of progesterone receptor membrane component-1 (PGRMC1) in premature ovarian failure.
P2860
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P2860
Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes.
@en
Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes.
@nl
type
label
Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes.
@en
Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes.
@nl
prefLabel
Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes.
@en
Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes.
@nl
P2093
P1433
P1476
Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes
@en
P2093
Andrew J Link
David W Powell
James Eckstein
Martin Bard
Peter J Espenshade
Robert Barbuch
P304
P356
10.1016/J.CMET.2006.12.009
P577
2007-02-01T00:00:00Z