The kinase activities of interleukin-1 receptor associated kinase (IRAK)-1 and 4 are redundant in the control of inflammatory cytokine expression in human cells.
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Toll-Like Receptors in the Pathogenesis of Autoimmune DiseasesRole of innate immunity in the development of hepatocellular carcinomaIRAK-4 inhibitors for inflammationProtective effect of diallyl trisulfide on liver in rats with sepsis and the mechanismT granules in human platelets function in TLR9 organization and signaling.A modeling-derived hypothesis on chronicity in respiratory diseases: desensitized pathogen recognition secondary to hyperactive IRAK/TRAF6 signaling.Gene signatures in wound tissue as evidenced by molecular profiling in the chick embryo model.Interleukin 1 receptor 1 and interleukin 1β regulate megakaryocyte maturation, platelet activation, and transcript profile during inflammation in mice and humans.Deregulation of microRNA expression in the different genetic subtypes of multiple myeloma and correlation with gene expression profiling.Kaposi's sarcoma-associated herpesvirus microRNAs target IRAK1 and MYD88, two components of the toll-like receptor/interleukin-1R signaling cascade, to reduce inflammatory-cytokine expression.IRAK4 kinase activity is not required for induction of endotoxin tolerance but contributes to TLR2-mediated toleranceInherited human IRAK-1 deficiency selectively impairs TLR signaling in fibroblastsRegulation of Transforming Growth Factor β-Activated Kinase Activation by Epigallocatechin-3-Gallate in Rheumatoid Arthritis Synovial Fibroblasts: Suppression of K(63) -Linked Autoubiquitination of Tumor Necrosis Factor Receptor-Associated Factor 6.Toll-like receptor signaling pathways--therapeutic opportunities.Role of Toll-like receptors in liver health and disease.The Role of Toll-Like Receptors in Autoimmune Diseases through Failure of the Self-Recognition Mechanism.The IRAK-ERK-p67phox-Nox-2 axis mediates TLR4, 2-induced ROS production for IL-1β transcription and processing in monocytesInhibitors of interleukin-1 receptor-associated kinase 4 (IRAK4): a patent review (2012-2015).IRAK1 and IRAK4 promote phosphorylation, ubiquitination, and degradation of MyD88 adaptor-like (Mal).Interleukin 1/Toll-like receptor-induced autophosphorylation activates interleukin 1 receptor-associated kinase 4 and controls cytokine induction in a cell type-specific mannerComplete dependence on IRAK4 kinase activity in TLR2, but not TLR4, signaling pathways underlies decreased cytokine production and increased susceptibility to Streptococcus pneumoniae infection in IRAK4 kinase-inactive miceDiscovery and Structure Enabled Synthesis of 2,6-Diaminopyrimidin-4-one IRAK4 InhibitorsMembrane-bound toll-like receptors are overexpressed in peripheral blood and synovial fluid mononuclear cells of enthesitis-related arthritis category of juvenile idiopathic arthritis (JIA–ERA) patients and lead to secretion of inflammatory mediatorMechanism of dysfunction of human variants of the IRAK4 kinase and a role for its kinase activity in interleukin-1 receptor signalingInterleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling
P2860
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P2860
The kinase activities of interleukin-1 receptor associated kinase (IRAK)-1 and 4 are redundant in the control of inflammatory cytokine expression in human cells.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
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2009年學術文章
@zh-hant
name
The kinase activities of inter ...... ine expression in human cells.
@en
The kinase activities of interleukin-1 receptor associated kinase
@nl
type
label
The kinase activities of inter ...... ine expression in human cells.
@en
The kinase activities of interleukin-1 receptor associated kinase
@nl
prefLabel
The kinase activities of inter ...... ine expression in human cells.
@en
The kinase activities of interleukin-1 receptor associated kinase
@nl
P2093
P1433
P1476
The kinase activities of inter ...... ine expression in human cells.
@en
P2093
Anthony M Manning
Brian R Wong
Francisco X Talamas
Jim W Barnett
Kelly D Thompson
Kyung W Song
Mohammad Hekmat-Nejad
Pam S Olson
Rebecca T Suttmann
Ronald J Hill
P304
P356
10.1016/J.MOLIMM.2008.12.012
P577
2009-01-31T00:00:00Z