Mechanical induction of the tumorigenic β-catenin pathway by tumour growth pressure.
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Changes in cellular mechanical properties during onset or progression of colorectal cancerTumor-induced solid stress activates β-catenin signaling to drive malignant behavior in normal, tumor-adjacent cellsMechanosensory Signaling in Enterochromaffin Cells and 5-HT Release: Potential Implications for Gut InflammationImpact of the physical microenvironment on tumor progression and metastasisCell-like pressure sensors reveal increase of mechanical stress towards the core of multicellular spheroids under compression.MicroRNA-27a promotes podocyte injury via PPARγ-mediated β-catenin activation in diabetic nephropathy.Flattened microvessel independently predicts poor prognosis of patients with non-small cell lung cancer.Mechanical Signals Inhibit Growth of a Grafted Tumor In Vivo: Proof of ConceptInsight On Colorectal Carcinoma Infiltration by Studying Perilesional Extracellular Matrix.A toolbox to explore the mechanics of living embryonic tissues.Mechanotransduction activates canonical Wnt/β-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valvesIncreasing β-catenin/Wnt3A activity levels drive mechanical strain-induced cell cycle progression through mitosis.Reengineering the Tumor Microenvironment to Alleviate Hypoxia and Overcome Cancer Heterogeneity.Systemic Wound Healing Associated with local sub-Cutaneous Mechanical Stimulation.Contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity.Growth-induced stress enhances epithelial-mesenchymal transition induced by IL-6 in clear cell renal cell carcinoma via the Akt/GSK-3β/β-catenin signaling pathway.Molecular imaging of aberrant crypt foci in the human colon targeting glutathione S-transferase P1-1.The size-speed-force relationship governs migratory cell response to tumorigenic factors.Nucleostemin promotes the proliferation of human glioma via Wnt/β-Catenin pathway.Adherens Junction and E-Cadherin complex regulation by epithelial polarity.Aberrant expression and functions of protocadherins in human malignant tumors.Taking the strain: quantifying the contributions of all cell behaviours to changes in epithelial shape.Life behind the wall: sensing mechanical cues in plants.Mechanosensitive Piezo Channels in the Gastrointestinal Tract.Molecular genetics and targeted therapy of WNT-related human diseases (Review).Predicting the growth of glioblastoma multiforme spheroids using a multiphase porous media model.Matrix stiffness induces epithelial-mesenchymal transition and promotes chemoresistance in pancreatic cancer cells.Canonical and non-canonical WNT signaling in cancer stem cells and their niches: Cellular heterogeneity, omics reprogramming, targeted therapy and tumor plasticity (Review)Intestinal Stem Cell Niche Insights Gathered from Both In Vivo and Novel In Vitro Models.Integrated in silico and experimental methods revealed that Arctigenin inhibited angiogenesis and HCT116 cell migration and invasion through regulating the H1F4A and Wnt/β-catenin pathway.Emergent cellular self-organization and mechanosensation initiate follicle pattern in the avian skin.Src- and confinement-dependent FAK activation causes E-cadherin relaxation and β-catenin activity.Regulation of genome organization and gene expression by nuclear mechanotransduction.Optimal Contractile Forces for a Mesenchymal Engine.Modeling mechanical interactions in growing populations of rod-shaped bacteria.Evaluating the influence of mechanical stress on anticancer treatments through a multiphase porous media model.Magnetic control of cellular processes using biofunctional nanoparticles.Hybrid cell-centred/vertex model for multicellular systems with equilibrium-preserving remodelling.An evolutionary perspective on field cancerization.Tissue Force Programs Cell Fate and Tumor Aggression.
P2860
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P2860
Mechanical induction of the tumorigenic β-catenin pathway by tumour growth pressure.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
Mechanical induction of the tumorigenic β-catenin pathway by tumour growth pressure.
@en
Mechanical induction of the tumorigenic β-catenin pathway by tumour growth pressure.
@nl
type
label
Mechanical induction of the tumorigenic β-catenin pathway by tumour growth pressure.
@en
Mechanical induction of the tumorigenic β-catenin pathway by tumour growth pressure.
@nl
prefLabel
Mechanical induction of the tumorigenic β-catenin pathway by tumour growth pressure.
@en
Mechanical induction of the tumorigenic β-catenin pathway by tumour growth pressure.
@nl
P2093
P2860
P50
P356
P1433
P1476
Mechanical induction of the tumorigenic β-catenin pathway by tumour growth pressure
@en
P2093
Aude Michel
Audrey Claperon
Chantal Housset
Colette Rey
Elodie Girard
Gaëlle Béalle
Heldmuth Latorre-Ossa
Hélène Marie
Laura Brullé
Sandrine Barbier
P2860
P2888
P356
10.1038/NATURE14329
P407
P50
P577
2015-05-11T00:00:00Z