2-Substituted 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Inhibition of Adenosine Kinases, and Antimycobacterial Activity.

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South (S)- and North (N)-Methanocarba-7-Deazaadenosine Analogues as Inhibitors of Human Adenosine Kinase.Pyrrolo[2,3-d]pyrimidine (7-deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides.

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P2860

2-Substituted 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Inhibition of Adenosine Kinases, and Antimycobacterial Activity.

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2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2-Substituted 6-(Het)aryl-7-de ...... nd Antimycobacterial Activity.

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2-Substituted 6-(Het)aryl-7-de ...... nd Antimycobacterial Activity.

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2-Substituted 6-(Het)aryl-7-de ...... nd Antimycobacterial Activity.

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2-Substituted 6-(Het)aryl-7-de ...... nd Antimycobacterial Activity.

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2-Substituted 6-(Het)aryl-7-de ...... nd Antimycobacterial Activity.

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2-Substituted 6-(Het)aryl-7-de ...... nd Antimycobacterial Activity.

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P1476

2-Substituted 6-(Het)aryl-7-de ...... and Antimycobacterial Activity

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P2093

Iva Pichová

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Jan Snášel

http://www.w3.org/2001/XMLSchema#string

Jiřina Stolaříková

http://www.w3.org/2001/XMLSchema#string

Lenka Poštová Slavětínská

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Petr Nauš

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Vincent Malnuit

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P2860

High resolution crystal structures of Mycobacterium tuberculosis adenosine kinase: insights into the mechanism and specificity of this novel prokaryotic enzyme

Structural basis for inhibition of mycobacterial and human adenosine kinase by 7-substituted 7-(Het)aryl-7-deazaadenine ribonucleosides

Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability

Synthesis of a 6-methyl-7-deaza analogue of adenosine that potently inhibits replication of polio and dengue viruses

Purine metabolism in Mycobacterium tuberculosis as a target for drug development.

Purine Salvage Pathway in Mycobacterium tuberculosis.

Synthesis, cytostatic, antimicrobial, and anti-HCV activity of 6-substituted 7-(het)aryl-7-deazapurine ribonucleosides.

Synthesis and cytostatic and antiviral activities of 2'-deoxy-2',2'-difluororibo- and 2'-deoxy-2'-fluororibonucleosides derived from 7-(Het)aryl-7-deazaadenines.

Synthesis and significant cytostatic activity of 7-hetaryl-7-deazaadenosines.

Phosphoramidate pronucleotides of cytostatic 6-aryl-7-deazapurine ribonucleosides.

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1079-1093

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scholarly article

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10.1002/CMDC.201500081

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Michal Hocek

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Marian Hajduch

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2015-04-16T00:00:00Z

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25882678

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2-Substituted 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Inhibition of Adenosine Kinases, and Antimycobacterial Activity.

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P2860

P2860

2-Substituted 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Inhibition of Adenosine Kinases, and Antimycobacterial Activity.

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